Photostable antioxidant cosmetic composition

Abstract

A composition includes polydatin and at least one photoisomerization stabilizer and a cosmetically acceptable carrier. The at least one photoisomerization stabilizer confers photostabilization to trans-polydatin by at least about 5%, relative to an otherwise identical composition without the at least one photoisomerization stabilizer.

What is claimed is: 
     
         1 . A composition comprising:
 i) Polydatin (3,4′,5-trihydroxystibene-3-β-mono-D glucoside) present from about 0.05% to about 5.00% by weight based on the weight of the composition;   ii) at least one photoisomerization stabilizer present from about 0.1 to about 2.5% by weight based on the weight of the composition; and   iii) a cosmetically acceptable carrier;   
       wherein the at least one photoisomerization stabilizer confers photostabilization to the polydatin by at least 5%, relative to an otherwise identical composition without the at least one photoisomerization stabilizer. 
     
     
         2 . The composition according to  claim 1 , wherein the photoisomerization stabilizer comprises at least one polyphenol, present in the composition from about 0.2% to about 0.4% by weight based on the weight of the composition. 
     
     
         3 . The composition according to  claim 1 , wherein the photoisomerization stabilizer comprises at least two polyphenols, each present in the composition from about 0.1% to about 2.5% by weight based on the weight of the composition. 
     
     
         4 . The composition according to  claim 1 , wherein the photoisomerization stabilizer comprises one or a combination of a flavanone, a flavanonol, a flavone, a hydroxycinnamate, and a xanthonoid. 
     
     
         5 . The composition according to  claim 5 , wherein the cosmetically acceptable carrier comprises one or a combination of: water present from about 45% to about 55%, one or more alcohol present from about 35% to about 40%, and one or more glycol present from about 0.5% to about 3.0%, each present by weight based on the weight of the composition. 
     
     
         6 . The composition according to  claim 1 , further comprising at least one additive. The composition according to  claim 6 , wherein the at least one additive includes one or more thickeners comprising one or a combination of natural and synthetic polymers. 
     
     
         8 . The composition according to  claim 1 , wherein the one or more thickeners comprises hydroxypropoylmethylcellulose, present from about 0.05% to about 5% by weight based on the weight of the composition. 
     
     
         9 . The composition according to  claim 1 , wherein the composition is monophasic and essentially free of oil. 
     
     
         10 . The composition according to  claim 1 , wherein the at least one photoisomerization stabilizer confers photostabilization to the polydatin from about at least 5% to about 90%, relative to an otherwise identical composition without the at least one photoisomerization stabilizer. 
     
     
         11 . A biphase aqueous composition comprising:
 i) Polydatin present from about 0.05% to about 5.00% by weight based on the weight of the composition;   ii) a photoisomerization stabilizer that comprises at least two polyphenols, each present in the composition from about 0.1% to about 2.5% by weight based on the weight of the composition; and   iii) a cosmetically acceptable carrier that comprises one or a combination of: water present from about 45% to about 55%, one or more alcohol present from about 35% to about 40%, and one or more glycol present from about 0.5% to about 3.0%, each present by weight based on the weight of the composition   
       wherein the at least one photoisomerization stabilizer confers photostabilization to the polydatin by at least 5%, relative to an otherwise identical composition without the at least one photoisomerization stabilizer, and wherein the composition is essentially free of oil. 
     
     
         12 . The composition according to  claim 11 , wherein the photoisomerization stabilizer comprises one or a combination of sodium tetracarboxymethylchalcone, Glycosyl Hesperidin, Hesperetin, Hesperidine, Silymarin, Taxifolin, Apigenin, Baicalein, Baicalin, Luteolin, Quercetin, Hydroxycinnamate, Ferulic acid, Oryzanol, p-coumaric acid, and Mangiferin. 
     
     
         13 . A photo-stabilized composition comprising:
 i) Polydatin present from about 0.05% to about 5.00% by weight based on the weight of the composition;   ii) a photoisomerization stabilizer comprising one or a mixture of polyphenols, each present by weight based on the weight of the composition, and selected from
 1. Caffeic acid present from about 0.2%; 
 2. Luteolin present from about 0.2%; 
 3. Hesperidine present from about 0.4%; 
 4. Sodium tetracarboxymethylchalcone present from about 0.4%; 
 5. Mangiferin present from about 0.25%; 
 6. Ferulic Acid present from about 0.2%; and 
   iii) a cosmetically acceptable carrier that includes water, at least one alcohol and at least one glycol;   
       wherein the at least one photoisomerization stabilizer confers radiation stabilization to the polydatin by at least 5%, relative to an otherwise identical composition without the at least one photoisomerization stabilizer. 
     
     
         14 . The photo-stabilized composition according to  claim 13 , the photoisomerization stabilizer comprising a mixture of polyphenols, the mixture selected from the group consisting of:
 i) luteolin present from about 0.2% by weight, hesperidine present from about 0.4% by weight, and sodium tetracarboxymethylchalcone present from about 0.4% by weight, each based on the weight of the composition;   ii) luteolin present from about 0.2% by weight, mangiferin present from about 0.25% by weight, and ferulic acid present from about 0.2% by weight, each based on the weight of the composition;   iii) luteolin present from about 0.2% by weight, and mangiferin present from about 0.25% by weight, each based on the weight of the composition;   iv) sodium tetracarboxymethylchalcone present from about 0.4% by weight, and ferulic acid present from about 0.2% by weight, each based on the weight of the composition;   v) luteolin present from about 0.2% by weight, and ferulic acid present from about 0.2% by weight, each based on the weight of the composition;   vi) caffeic acid present from about 0.2% by weight, luteolin present from about 0.2% by weigh, and mangiferin present from about 0.25% by weight, each based on the weight of the composition;   vii) caffeic acid present from about 0.2% by weight, and ferulic acid present from about 0.2% by weight, each based on the weight of the composition.   
     
     
         15 . The photo-stabilized composition according to  claim 14 , the cosmetically acceptable carrier comprises one or a combination of water present from about 45% to about 55%, an alcohol present from about 35% to about 40%, and a glycol present from about 0.5% to about 3.0%, each present by weight based on the weight of the composition.