US2020353438A1PendingUtilityA1

Method of fabricating cell arrays and uses thereof

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Assignee: STEMONIX INCPriority: Aug 28, 2014Filed: Jan 9, 2020Published: Nov 12, 2020
Est. expiryAug 28, 2034(~8.1 yrs left)· nominal 20-yr term from priority
B01J 2219/00531B01J 19/0046B01J 2219/00639C12M 25/14C12N 5/0606C12N 5/0696C12N 5/0657B01J 2219/00743B01J 2219/00362C12N 2531/00G01N 33/5073B01J 2219/00711G01N 33/5008
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Claims

Abstract

The present disclosure provides a fabrication process that results in creating large arrays of living cells, such as stem cells, which are subsequently exposed to nanoliter quantities of compounds to test the efficacy on cellular metabolism.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A method of fabricating and dosing a stem cell array, comprising:
 providing a mixture of cells and a UV curable hydrogel matrix;   applying a volume of the mixture in N×N array to a support and optionally providing for a specific geometry for the applied volume;   exposing the support to UV light to cure each volume in the array and optionally incubating the array under conditions that provide for cell viability; and   contacting the array with one or more compounds.

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