US2020384057A1PendingUtilityA1

Composition for enhancing immunity or preventing or treating neurodegenerative diseases by using goji berries, mulberries and jujubes

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Assignee: COSMAX NS INCPriority: Jan 5, 2018Filed: Apr 27, 2018Published: Dec 10, 2020
Est. expiryJan 5, 2038(~11.5 yrs left)· nominal 20-yr term from priority
A23L 33/105A61K 2236/00A61K 36/605A23V 2200/324A61K 36/725A23V 2002/00A61K 2300/00A61P 37/00A61K 36/815A61P 25/00A23V 2200/322A61K 2236/51
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Claims

Abstract

The present invention relates to a composition for enhancing immunity or a composition for preventing or ameliorating neurodegenerative diseases, both of which contain, as an active ingredient, a mixture extract of goji berries, mulberries and jujubes or an extract mixture thereof.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A pharmaceutical composition for enhancing immunity comprising a mixture extract of goji berries, mulberries and jujubes or an extract mixture thereof as an active ingredient. 
     
     
         2 . The pharmaceutical composition for enhancing immunity according to  claim 1 , wherein the weight ratio of goji berry:mulberry:jujube is 1 to 3:1 to 3:0.5 to 1.5. 
     
     
         3 . The pharmaceutical composition for enhancing immunity according to  claim 1 , wherein the mixture extract or the extract mixture is lyophilized or spray dried. 
     
     
         4 . The pharmaceutical composition for enhancing immunity according to  claim 1 , wherein the mixture extract or the extract mixture increases macrophage-derived TNF-α expression. 
     
     
         5 . The pharmaceutical composition for enhancing immunity according to  claim 1 , wherein the total concentration of the mixture extract or the extract mixture is 1 μg/ml to 10 mg/ml. 
     
     
         6 . A health functional food for enhancing immunity comprising a mixture extract of goji berries, mulberries and jujubes or an extract mixture thereof as an active ingredient. 
     
     
         7 . A pharmaceutical composition for preventing or treating neurodegenerative diseases comprising a mixture extract of goji berries, mulberries and jujubes or an extract mixture thereof as an active ingredient. 
     
     
         8 . The pharmaceutical composition for preventing or treating neurodegenerative diseases according to  claim 7 , wherein the weight ratio of goji berry:mulberry:jujube is 1 to 3:1 to 3:0.5 to 1.5. 
     
     
         9 . The pharmaceutical composition for preventing or treating neurodegenerative diseases according to  claim 7 , wherein the mixture extract or the extract mixture is lyophilized or spray dried. 
     
     
         10 . The pharmaceutical composition for preventing or treating neurodegenerative diseases according to  claim 7 , wherein the mixture extract or the extract mixture increases the ratio of mBDNF (mature BDNF) to hippocampal total BDNF. 
     
     
         11 . The pharmaceutical composition for preventing or treating neurodegenerative diseases according to  claim 7 , wherein the total concentration of the mixture extract or the extract mixture is 1 μg/ml to 10 mg/ml. 
     
     
         12 . The pharmaceutical composition for preventing or treating neurodegenerative diseases according to  claim 7 , wherein the neurodegenerative disease is selected from the group consisting of cerebral infarction, stroke, amnesia, memory impairment, dementia, forgetfulness, Parkinson's disease, Alzheimer's disease, Pick's disease, Creutzfeld-Kacob disease, Huntington's disease, and amyotrophic lateral sclerosis. 
     
     
         13 . A health functional food for preventing or ameliorating neurodegenerative diseases comprising a mixture extract of goji berries, mulberries and jujubes or an extract mixture thereof as an active ingredient.

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