Nanoemulsions with color stabilized actives

Abstract

Nanoemulsions as emulsion additives are prepared to stabilize actives and prevent formulation discoloration. The nanoemulsions have at least 30% by weight oil and are suitable to add to emulsions and/or structured water to produce color stable end use skin benefit compositions.

1 . Nanoemulsion comprising:
 (a) active;   (b) water;   (c) water soluble humectant   (d) oil; and   (e) emulsifier   wherein the active is soluble in the oil, the nanoemulsion has a particle size from 0.05 to less than 1.5 microns and comprises at least 30% by weight oil; wherein the oil is a mineral oil, wherein the active is A, B or a mixture thereof;   wherein A is represented by the formula:   
       
         
           
           
               
               
           
         
         where each R is independently a hydrogen or a C 1-6  alkyl group and X is 
       
       
         
           
           
               
               
           
         
         and further where each R′ is hydrogen or a C 1 -C 3  alkyl and n is an integer from 0 to 16; and 
         wherein B is resorcinol, 4-ethyl resorcinol, 4-hexyl resorcinol, 4-phenylethyl resorcinol, 4-cyclopentyl resorcinol, 4-cyclohexyl resorcinol 4-isopropyl resorcinol, a 5-substituted resorcinol or a mixture thereof. 
       
     
     
         2 . (canceled) 
     
     
         3 . The nanoemulsion according to  claim 1  wherein the emulsifier has an HLB from 7-17. 
     
     
         4 . The nanoemulsion according to  claim 1 , wherein the water soluble humectant is glycerine. 
     
     
         5 . The nanoemulsion according to  claim 1  the nanoemulsion has a particle size from 0.1 to 0.8 microns. 
     
     
         6 . An end use skin benefit composition comprising the nanoemulsion of  claim 1 . 
     
     
         7 . The end use skin benefit composition according to  claim 6  wherein the nanoemulsion has a particle size of 0.1 to 0.8 microns, the nanoemulsion makes up from about 30 to 60 percent by weight of the composition. 
     
     
         8 . The end use composition according to  claim 6  wherein the nanoemulsion is an oil in water emulsion and active is present in the oil at 0.01 to 6% based on total weight of the nanoemulsion wherein the nanoemulsion comprises from 30 to 65% by weight oil. 
     
     
         9 . (canceled) 
     
     
         10 . The end use skin benefit composition according to  claim 6  wherein the active is retinol, retinal, retinyl propionate, retinyl palmitate, retinyl acetate, or a mixture thereof. 
     
     
         11 . The end use skin benefit composition according to  claim 6  wherein the active is resorcinol, 4-ethyl resorcinol, 4-hexyl resorcinol, 4-phenylethyl resorcinol, 4-cyclopentyl resorcinol, 4-cyclohexyl resorcinol 4-isopropyl resorcinol, a 5-substituted resorcinol or a mixture thereof. 
     
     
         12 . (canceled) 
     
     
         13 . A method for preventing composition discoloration by preparing and end use composition with nanoemulsion dispersed therein, the nanoemulsion comprising oil soluble active dissolved in the oil phase of the nanoemulsion, at least 30% by weight oil and a particle size from 0.05 to less than 1.5 microns.