US2021053999A1PendingUtilityA1

Tricyclic Benzoxaborole Compounds and Uses Thereof

Assignee: GLAXOSMITHKLINE IP NO 2 LTDPriority: Aug 9, 2013Filed: Nov 4, 2020Published: Feb 25, 2021
Est. expiryAug 9, 2033(~7.1 yrs left)· nominal 20-yr term from priority
C07F 5/025A61P 1/04A61P 17/00C07F 5/04A61P 35/00A61K 31/69A61P 31/04A61K 45/06A61P 11/00A61P 15/00A61P 31/06A61P 43/00A61P 21/00
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Claims

Abstract

Compounds of Formula II, wherein X is selected from chloro, fluoro, bromo and iodo, R 1 and R 2 are each independently selected from H, —CH 3 , —CH 2 CH 3 , —CH 2 CH 2 CH 3 , or —CH(CH 3 ) 2 ; compositions containing them, their use in therapy, including their use as anti-mycobacterial agents, for example in the treatment of a mycobacterial infection in a mammal, and methods for the preparation of such compounds, are provided.

Claims

exact text as granted — not AI-modified
1 . A compound having a structure as shown in Formula II: 
       
         
           
           
               
               
           
         
         wherein X is selected from chloro or bromo and R 1  and R 2  are each independently selected from H and —CH 3 ; or a pharmaceutically acceptable salt thereof. 
       
     
     
         2 - 21 . (canceled)

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