US2021093595A1PendingUtilityA1

Non-pharmaceutical bactericidal composition against helicobacter pylori

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Assignee: ECO GEO BIO TECH COMPANY LIMITEDPriority: Sep 27, 2019Filed: Nov 14, 2019Published: Apr 1, 2021
Est. expirySep 27, 2039(~13.2 yrs left)· nominal 20-yr term from priority
A61K 47/12A61K 9/0053A61K 31/375A61K 31/194A61K 9/0056A61K 47/22
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Claims

Abstract

The present invention provides a non-pharmaceutical bactericidal composition against a Helicobacter pylori, including a first daily edible component and a second daily edible component, wherein the first daily edible component has a molecular state and a dissociated state while in an aqueous solution state, the first daily edible component of the molecular state is used for performing functions of killing the Helicobacter pylori and inhibiting an ascorbate oxidase activity of the Helicobacter pylori in an environment with a pH value below 5, and the first daily edible component is a citric acid, a malic acid or a combination thereof, and wherein the second daily edible component is a salt used to form a buffer combination with the first daily edible component, and used to neutralize a bicarbonate, so that the first daily edible component can continue its killing of the Helicobacter pylori effectively and inhibiting the ascorbate oxidase activity of the Helicobacter pylori, and the salt is a salt of the citric acid, a salt of the malic acid or a combination thereof.

Claims

exact text as granted — not AI-modified
1 . A non-pharmaceutical bactericidal composition against a  Helicobacter pylori , the non-pharmaceutical bactericidal composition comprising:
 a first daily edible component being malic acid;   a used to form a buffer combination with the malic acid wherein the salt is sodium malate; and   a second daily edible component being ascorbic acid.   
     
     
         2 . The non-pharmaceutical bactericidal composition as claimed in  claim 1 , wherein the ascorbic acid has a concentration being in a range from 3000 ppm to 10000 ppm. 
     
     
         3 . The non-pharmaceutical bactericidal composition as claimed in  claim 1 , wherein the ascorbic acid has a concentration of 9000 ppm. 
     
     
         4 . (canceled) 
     
     
         5 . A non-pharmaceutical bactericidal composition against a  Helicobacter pylori , the non-pharmaceutical bactericidal composition comprising:
 a first daily edible component being a buffer combination consisting of an organic acid and a salt of the organic acid, wherein the organic acid is malic acid and   a second daily edible being ascorbic acid.   
     
     
         6 . The non-pharmaceutical bactericidal composition as claimed in  claim 5 , wherein the non-pharmaceutical bactericidal composition has a pH value below 5. 
     
     
         7 . The non-pharmaceutical bactericidal composition as claimed in  claim 5 , wherein the non-pharmaceutical bactericidal composition has a pH value being in a range from 3 to 5. 
     
     
         8 . The non-pharmaceutical bactericidal composition as claimed in  claim 5 , wherein the non-pharmaceutical bactericidal composition has a pH value of 3. 
     
     
         9 . A non-pharmaceutical bactericidal composition against a  Helicobacter pylori , the non-pharmaceutical bactericidal composition comprising:
 a first daily edible component being malic acid; and   a second daily edible component, being a salt, used to form a buffer combination with the first daily edible component, malic acid,   wherein the non-pharmaceutical bactericidal composition has a pH value of 3.   
     
     
         10 . (canceled) 
     
     
         11 . The non-pharmaceutical bactericidal composition as claimed in  claim 9 , wherein the salt is sodium malate. 
     
     
         12 . The non-pharmaceutical bactericidal composition as claimed in  claim 9 , further comprising an ascorbic acid for killing the  Helicobacter pylori  more thoroughly in presence of the first daily edible component and the second daily edible component. 
     
     
         13 . A method for treating a  Helicobacter pylori  infection, the method comprising steps of:
 providing a non-pharmaceutical bactericidal composition including a first daily edible component and a second daily edible component, wherein the first daily edible component has a molecular state and a dissociated state while in an aqueous solution state, the first daily edible component of the molecular state is used for performing functions of killing a  Helicobacter pylori  and inhibiting an ascorbate oxidase activity of the  Helicobacter pylori  in an environment with a pH value below 5, the first daily edible component is a citric acid, a malic acid or a combination thereof, and the second daily edible component is a salt, is used to form a buffer combination with the first daily edible component, and is used to neutralize a bicarbonate, so that the first daily edible component can continue its killing of the  Helicobacter pylori  effectively and inhibiting the ascorbate oxidase activity of the  Helicobacter pylori , wherein the salt is a salt of the citric acid, a salt of the malic acid or a combination thereof; and   administering the non-pharmaceutical bactericidal composition to a mammal.   
     
     
         14 . The method as claimed in  claim 13 , wherein the ascorbic acid has a concentration being in a range from 3000 ppm to 10000 ppm. 
     
     
         15 . The method as claimed in  claim 13 , wherein the ascorbic acid has a concentration of 9000 ppm. 
     
     
         16 . The method as claimed in  claim 13 , wherein the non-pharmaceutical bactericidal composition has a pH value below 5. 
     
     
         17 . The method as claimed in  claim 13 , wherein the non-pharmaceutical bactericidal composition has a pH value being in a range from 3 to 5. 
     
     
         18 . The method as claimed in  claim 13 , wherein the non-pharmaceutical bactericidal composition has a pH value of 3. 
     
     
         19 . The method as claimed in  claim 13 , wherein the non-pharmaceutical bactericidal composition further comprises an ascorbic acid for killing the  Helicobacter pylori  more thoroughly in the presence of the first daily edible component and the second daily edible component. 
     
     
         20 . The method as claimed in  claim 13 , wherein the mammal is a human being.

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