US2021113624A1PendingUtilityA1

Somatic stem cells

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Assignee: STEMBIOS TECH INCPriority: Aug 4, 2010Filed: Jun 30, 2020Published: Apr 22, 2021
Est. expiryAug 4, 2030(~4.1 yrs left)· nominal 20-yr term from priority
Inventors:James Wang
A61K 35/15C12N 5/0639A61K 2039/5154A61K 39/0011A61K 2035/124C12N 2506/03C12N 2501/115A61P 37/04C12N 5/0652G01N 33/5091A61K 35/28C12N 2501/91C12N 2501/2303C12N 2500/10C12N 2506/11A61P 25/28A61K 9/0019C12N 2501/22C12N 5/0662C12N 2506/00A61P 25/00A61P 35/02C12N 2501/135A61P 1/16C12N 2501/11C12N 2501/125A61P 35/00A61K 35/14A61P 25/16
72
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Claims

Abstract

Described herein is a method of treating a disorder, the method comprising: administering to a subject in need thereof a composition that contains a population of somatic stem cells that are 0.3-6.0 micrometers in size and CD9+, CD349+, CD133−, CD90−, CD34−, SSEA1+, SSEA4+, CD13+, or Stro1+, wherein the disorder is hair loss, osteoporosis, or a damaged tissue.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A method of treating a disorder, the method comprising:
 administering to a subject in need thereof a composition that contains a population of somatic stem cells that are less than 6.0 micrometers in size and CD9+, CD349+, CD133−, CD90−, CD34−, SSEA1+, SSEA4+, CD13+, or Stro1+;   wherein the disorder is hair loss, osteoporosis, or a damaged tissue.   
     
     
         2 . The method of  claim 1 , wherein the population of somatic stem cells are CD9+, CD349+, and CD133−. 
     
     
         3 . The method of  claim 1 , wherein the population of somatic stem cells are obtained by a procedure including:
 incubating a bodily fluid sample with EDTA in a container until the sample is separated into an upper layer and a lower layer; and   collecting the upper layer, wherein the upper layer contains the population of somatic stem cells.   
     
     
         4 . The method of  claim 1 , wherein the administering step is performed by injecting the composition to the subject intravenously. 
     
     
         5 . The method of  claim 4 , wherein the composition contains 1×10 6 ˜10 11  of the somatic stem cells. 
     
     
         6 . The method of  claim 3 , wherein the bodily fluid sample is a human sample. 
     
     
         7 . The method of  claim 6 , wherein the bodily fluid sample is obtained from the subject. 
     
     
         8 . The method of  claim 6 , wherein the bodily fluid sample is a blood or bone marrow sample. 
     
     
         9 . The method of  claim 1 , wherein the hair loss is male pattern baldness or alopecia areata. 
     
     
         10 . The method of  claim 1 , wherein the damaged tissue is a wound.

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