US2021121576A1PendingUtilityA1

Dermocosmetic compositions including glycerol-sebacate

59
Assignee: SECANT GROUP LLCPriority: Feb 21, 2018Filed: Jan 5, 2021Published: Apr 29, 2021
Est. expiryFeb 21, 2038(~11.6 yrs left)· nominal 20-yr term from priority
Inventors:Peter D. GabrieleJeremy J. HarrisCarissa SmootCharles Brendan NicholsonStephanie M. ReedRyan R. Smalley
A61K 47/34A61Q 19/00A61K 8/85A61Q 19/08A61L 27/54A61K 8/375A61L 2430/20A61P 17/02A61L 27/34A61K 9/7023A61K 45/06
59
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Claims

Abstract

A method of forming a skin care product includes combining at least one additive including at least one active ingredient with at least one glycerol-sebacate component having repeating units of (glycerol sebacate), water, a co-solvent, and at least one of an emulsifier, a surfactant, and a bodying agent to form the skin care product. A dermocosmetic composition includes at least one additive including at least one active ingredient and at least one glycerol-sebacate component having repeating units of (glycerol sebacate). A method of skin care includes applying a dermocosmetic composition to a skin surface.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A method of skin care comprising:
 applying a dermocosmetic composition to a skin surface, the dermocosmetic composition comprising:
 at least one additive comprising at least one active ingredient; and 
 at least one glycerol-sebacate component having repeating units of (glycerol sebacate). 
   
     
     
         2 . The method of  claim 1 , wherein the at least one additive is selected from the group consisting of cholesterol, a small chain fatty acid, a glycolic acid, a lactic acid, arbutin, vitamin B, vitamin D, estrogen, an antioxidant, lauric acid, an amino acid, magnesium oxide, decanoic acid, retinoic acid, nicotinamide, B-carotene, resveratrol, a natural light-active compound, a radical-active compound, and combinations thereof. 
     
     
         3 . The method of  claim 1 , wherein the at least one active ingredient is selected from the group consisting of an alpha-hydroxy acid, a beta-hydroxy acid, salicylic acid, citric acid, a curcuminoid, hydroquinone, kojic acid, retinol, L-ascorbic acid, hyaluronic acid, copper peptide, alpha-lipoic acid, niacinamide, a ceramide, a peptide, vitamin E, dimethylaminoethanol, and combinations thereof. 
     
     
         4 . The method of  claim 1 , wherein the at least one glycerol-sebacate component is selected from the group consisting of poly(glycerol sebacate), oligomeric (glycerol sebacate), and thermoset poly(glycerol sebacate) flour. 
     
     
         5 . The method of  claim 1 , wherein the dermocosmetic composition further comprises water, a co-solvent, and a component selected from the group consisting of an emulsifier, a surfactant, a bodying agent, and combinations thereof. 
     
     
         6 . The method of  claim 1 , wherein the at least one glycerol-sebacate component is applied for the purpose of altering an expression of at least one gene in skin after application of the dermocosmetic composition to the skin surface. 
     
     
         7 . A dermocosmetic composition comprising:
 at least one additive comprising at least one active ingredient; and   at least one glycerol-sebacate component having repeating units of (glycerol sebacate).   
     
     
         8 . The dermocosmetic composition of  claim 7 , wherein the at least one additive is covalently attached to the at least one glycerol-sebacate component. 
     
     
         9 . The dermocosmetic composition of  claim 7 , wherein the at least one additive is selected from the group consisting of cholesterol, a small chain fatty acid, a glycolic acid, a lactic acid, arbutin, vitamin B, vitamin D, estrogen, an antioxidant, lauric acid, an amino acid, magnesium oxide, decanoic acid, retinoic acid, nicotinamide, B-carotene, resveratrol, a natural light-active compound, a radical-active compound, and combinations thereof. 
     
     
         10 . The dermocosmetic composition of  claim 7 , wherein the at least one active ingredient is selected from the group consisting of an alpha-hydroxy acid, a beta-hydroxy acid, salicylic acid, citric acid, a curcuminoid, hydroquinone, kojic acid, retinol, L-ascorbic acid, hyaluronic acid, copper peptide, alpha-lipoic acid, niacinamide, a ceramide, a peptide, vitamin E, dimethylaminoethanol, and combinations thereof. 
     
     
         11 . The dermocosmetic composition of  claim 7 , wherein the at least one glycerol-sebacate component is selected from the group consisting of poly(glycerol sebacate), oligomeric (glycerol sebacate), and thermoset poly(glycerol sebacate) flour. 
     
     
         12 . The dermocosmetic composition of  claim 7  further comprising water, a co-solvent, and a component selected from the group consisting of an emulsifier, a surfactant, a bodying agent, and combinations thereof. 
     
     
         13 . The dermocosmetic composition of  claim 7 , wherein the at least one glycerol-sebacate component forms a matrix of the dermocosmetic composition. 
     
     
         14 . A method of forming a skin care product comprising:
 combining at least one additive comprising at least one active ingredient with at least one glycerol-sebacate component having repeating units of (glycerol sebacate), water, a co-solvent, and a component selected from the group consisting of an emulsifier, a surfactant, a bodying agent, and combinations thereof.   
     
     
         15 . The method of  claim 14 , wherein the combining further comprises covalently attaching the at least one additive to the at least one glycerol-sebacate component. 
     
     
         16 . The method of  claim 14 , wherein the at least one additive is selected from the group consisting of cholesterol, a small chain fatty acid, a glycolic acid, a lactic acid, arbutin, vitamin B, vitamin D, estrogen, an antioxidant, lauric acid, an amino acid, magnesium oxide, decanoic acid, retinoic acid, nicotinamide, B-carotene, resveratrol, a natural light-active compound, a radical-active compound, and combinations thereof. 
     
     
         17 . The method of  claim 14 , wherein the at least one active ingredient is selected from the group consisting of an alpha-hydroxy acid, a beta-hydroxy acid, salicylic acid, citric acid, a curcuminoid, hydroquinone, kojic acid, retinol, L-ascorbic acid, hyaluronic acid, copper peptide, alpha-lipoic acid, niacinamide, a ceramide, a peptide, vitamin E, dimethylaminoethanol, and combinations thereof. 
     
     
         18 . The method of  claim 14 , wherein the at least one glycerol-sebacate component is selected from the group consisting of poly(glycerol sebacate), oligomeric (glycerol sebacate), and thermoset poly(glycerol sebacate) flour. 
     
     
         19 . The method of  claim 14 , wherein the dermocosmetic composition further comprises water, a co-solvent, and a component selected from the group consisting of an emulsifier, a surfactant, a bodying agent, and combinations thereof. 
     
     
         20 . A method of skin care comprising:
 providing a dermocosmetic composition comprising at least one glycerol-sebacate component having repeating units of (glycerol sebacate), the dermocosmetic composition having an effective amount of the at least one glycerol-sebacate component to alter an expression of at least one gene in skin after application of the dermocosmetic composition to the skin surface; and   applying the dermocosmetic composition to a surface of the skin such that the expression of the at least one gene in the skin is altered by the at least one glycerol-sebacate component.

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