Medical use of compound iii

Abstract

and its use for treatment and/or prevention of diseases of the schizophrenia spectrum and other psychotic disorders, first episodes of these diseases such as first episode of psychosis (FEP), relapses of these diseases such as reduction of relapse in patients with schizophrenia (REX). The invention also relates to polymorphs of compound III, and pharmaceutical compositions comprising compound III and/or its polymorphs.

1 . A method of using Compound III 
       
         
           
           
               
               
           
         
         for treating, delaying or preventing a disorder selected from the group consisting of:
 Schizophrenia spectrum and other psychotic disorders, 
 Schizophrenia, 
 Psychosis, 
 Schizotypal (personality) disorder, 
 Delusional disorder, 
 Attenuated psychosis syndrome, 
 Brief psychotic disorder, 
 Schizophreniform disorder, 
 Schizoaffective disorder, 
 Substance/Medication-Induced Psychotic Disorder, 
 Psychotic Disorder, 
 Psychotic Disorder Due to Another Medical Condition, 
 Other Specified Schizophrenia Spectrum and Other Psychotic Disorders, 
 Unspecified Schizophrenia Spectrum and Other Psychotic Disorder, 
 Catatonia Associated With Another Mental Disorder, and 
 Catatonic Disorder Due to Another Medical Condition, the method comprising administering a pharmaceutically effective amount of Compound III, or a pharmaceutically salt thereof, to a patient in need thereof. 
 
       
     
     
         2 . The method according to  claim 1 , where the method is for treating, delaying, or preventing a first episode and/or relapse of the disorder. 
     
     
         3 . The method according to  claim 1  for preventing the disorder. 
     
     
         4 . The method according to  claim 1  for treating attenuated psychosis syndrome. 
     
     
         5 . The method according to  claim 2  for reducing relapse in schizophrenia. 
     
     
         6 . The method according to  claim 1  for preventing first-episode of psychosis. 
     
     
         7 . The method according to  claim 1 , further comprising administering Compound III, or a pharmaceutically acceptable salt thereof, in combination with another antipsychotic drug. 
     
     
         8 - 9 . (canceled) 
     
     
         10 . The method of  claim 1  for delaying the disorder. 
     
     
         11 . The method of  claim 2  for preventing the first episode and/or relapse of the disorder. 
     
     
         12 . The method of  claim 2  for delaying the first episode and/or relapse of the disorder.