US2021154152A1PendingUtilityA1

Gel patch

59
Assignee: HISAMITSU PHARMACEUTICAL COPriority: Feb 24, 2015Filed: Feb 4, 2021Published: May 27, 2021
Est. expiryFeb 24, 2035(~8.6 yrs left)· nominal 20-yr term from priority
Inventors:Seiichiro TsuruMasayoshi Maki
A61K 31/192A61K 47/02A61K 31/4468A61K 31/405A61K 31/196A61K 31/167A61K 9/7069A61K 9/7061A61K 2300/00A61K 47/32A61K 47/10A61K 45/00A61K 9/70A61K 9/7038
59
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Claims

Abstract

A method for producing a gel patch comprising an adhesive mass layer on a backing fabric, comprising a step of applying a composition comprising a physiologically active substance, a water-soluble polymer, glycerin, and water to the backing fabric to form the adhesive mass layer, wherein a loss tangent of the composition in dynamic viscoelasticity measurement at 1 Hz at a time of application to the backing fabric is 0.75 to 1.

Claims

exact text as granted — not AI-modified
1 - 8 . (canceled) 
     
     
         9 . A method for producing a gel patch comprising an adhesive mass layer on a backing fabric, comprising:
 a step of applying a composition comprising a physiologically active substance, a water-soluble polymer, glycerin, and water to the backing fabric to form the adhesive mass layer, wherein   a loss tangent of the composition in dynamic viscoelasticity measurement at 1 Hz at a time of application to the backing fabric is 0.75 to 1.   
     
     
         10 . The method according to  claim 9 , wherein
 the backing fabric is a knitted fabric, and   an elongation recovery ratio of the knitted fabric is 73 to 98% in a course direction and 83 to 98% in a wale direction.   
     
     
         11 . The method according to  claim 9 , wherein
 the backing fabric is a knitted fabric, and   a bending resistance of the knitted fabric is 10 to 15 mm in a course direction and 10 to 18 mm in a wale direction.   
     
     
         12 . The method according to  claim 9 , wherein
 the backing fabric is a knitted fabric, and   the knitted fabric has a value of a 50% modulus in a wale direction relative to a 50% modulus in a course direction of 0.8 to 1.2, and the modulus is measured as defined in JIS L 1018:1999.   
     
     
         13 . The method according to  claim 9 , wherein the water-soluble polymer comprises a polyacrylic acid or a neutralized polyacrylate. 
     
     
         14 . The method according to  claim 9 , wherein the composition comprises a methyl acrylate/2-ethylhexyl acrylate copolymer resin. 
     
     
         15 . The method according to  claim 9 , wherein a content of the water-soluble polymer is 3 to 18% by mass based on the mass of the whole adhesive mass layer. 
     
     
         16 . A gel patch, which is obtained by the method according to  claim 9 . 
     
     
         17 . The method according to  claim 10 , wherein
 the backing fabric is a knitted fabric, and   a bending resistance of the knitted fabric is 10 to 15 mm in a course direction and 10 to 18 mm in a wale direction.   
     
     
         18 . The method according to  claim 10 , wherein
 the backing fabric is a knitted fabric, and   the knitted fabric has a ratio of a 50% modulus in a wale direction relative to a 50% modulus in a course direction of 0.8 to 1.2, and the modulus is measured as defined in JIS L 1018:1999.   
     
     
         19 . The method according to  claim 11 , wherein
 the backing fabric is a knitted fabric, and   the knitted fabric has a ratio of a 50% modulus in a wale direction relative to a 50% modulus in a course direction of 0.8 to 1.2, and the modulus is measured as defined in JIS L 1018:1999.   
     
     
         20 . The method according to  claim 10 , wherein the water-soluble polymer comprises a polyacrylic acid or a neutralized polyacrylate. 
     
     
         21 . The method according to  claim 11 , wherein the water-soluble polymer comprises a polyacrylic acid or a neutralized polyacrylate. 
     
     
         22 . The method according to  claim 12 , wherein the water-soluble polymer comprises a polyacrylic acid or a neutralized polyacrylate. 
     
     
         23 . The method according to  claim 10 , wherein the composition comprises a methyl acrylate/2-ethylhexyl acrylate copolymer resin. 
     
     
         24 . The method according to  claim 11 , wherein the composition comprises a methyl acrylate/2-ethylhexyl acrylate copolymer resin. 
     
     
         25 . The method according to  claim 12 , wherein the composition comprises a methyl acrylate/2-ethylhexyl acrylate copolymer resin. 
     
     
         26 . The method according to  claim 10 , wherein a content of the water-soluble polymer is 3 to 18% by mass based on the mass of the whole adhesive mass layer. 
     
     
         27 . The method according to  claim 11 , wherein a content of the water-soluble polymer is 3 to 18% by mass based on the mass of the whole adhesive mass layer. 
     
     
         28 . The method according to  claim 12 , wherein a content of the water-soluble polymer is 3 to 18% by mass based on the mass of the whole adhesive mass layer.

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