US2021186904A1PendingUtilityA1

Methods and Compositions for Treatment of Asthma or Parkinson's Disease

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Assignee: INNOPHARMASCREEN INCPriority: Sep 6, 2018Filed: Mar 3, 2021Published: Jun 24, 2021
Est. expirySep 6, 2038(~12.2 yrs left)· nominal 20-yr term from priority
Inventors:Incheol KangJeseong Park
A61P 25/16A61K 9/0053A61K 31/47A61K 31/155A61P 11/06A61K 2300/00
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Claims

Abstract

The present invention relates to methods and compositions comprising proguanil for treating asthma. The invention also relates to methods and compositions comprising proguanil for treating Parkinson's disease.

Claims

exact text as granted — not AI-modified
1 .- 8 . (canceled) 
     
     
         9 . A pharmaceutical composition comprising a compound represented by Formula 1 or a pharmaceutically acceptable salt thereof, a compound represented by Formula 2 or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient: 
       
         
           
           
               
               
           
         
       
     
     
         10 . The composition of  claim 9 , wherein the composition is suitable for oral administration. 
     
     
         11 . The composition of  claim 9 , wherein the composition comprises 1 mg to 1000 mg of each of the compound. 
     
     
         12 . A method of treating Parkinson's disease in a subject in need thereof, the method comprising administering to the subject a pharmaceutical composition comprising a compound represented by Formula 1 or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable excipient: 
       
         
           
           
               
               
           
         
       
     
     
         13 . The method of  claim 12 , wherein the composition further comprises a compound represented by Formula 2 or a pharmaceutically acceptable salt thereof. 
       
         
           
           
               
               
           
         
       
     
     
         14 . The method of  claim 12 , wherein the composition is administered orally to the subject. 
     
     
         15 . The method of  claim 13 , wherein the composition is administered orally to the subject. 
     
     
         16 . The method of  claim 12 , wherein the composition comprises 0.001 mg to 100 mg of each of the compound per kg of the subject's body weight. 
     
     
         17 . The method of  claim 13 , wherein the composition comprises 0.001 mg to 100 mg of each of the compound per kg of the subject's body weight.

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