US2021196834A1PendingUtilityA1

Anti-sez6 antibody drug conjugates and methods of use

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Assignee: ABBVIE STEMCENTRX LLCPriority: May 30, 2018Filed: May 30, 2019Published: Jul 1, 2021
Est. expiryMay 30, 2038(~11.9 yrs left)· nominal 20-yr term from priority
Inventors:David LiuJulia GavrilyukAlexander Wayne Schammel
A61K 47/68C07K 16/28C07K 16/18A61P 35/00A61K 47/6857A61K 47/6849A61K 47/6835A61K 47/6809A61K 47/6807A61K 2039/505
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Claims

Abstract

Provided are novel anti-SEZ6 antibodies and antibody drug conjugates, and methods of using such anti-SEZ6 antibodies and antibody drug conjugates to treat cancer.

Claims

exact text as granted — not AI-modified
1 .- 19 . (canceled) 
     
     
         20 . A calicheamicin drug linker, or a pharmaceutically acceptable salt or solvate thereof, comprising the structure:

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