Integrated medicament delivery device for use with continuous analyte sensor

Abstract

An integrated system for the monitoring and treating diabetes is provided, including an integrated receiver/hand-held medicament injection pen, including electronics, for use with a continuous glucose sensor. In some embodiments, the receiver is configured to receive continuous glucose sensor data, to calculate a medicament therapy (e.g., via the integrated system electronics) and to automatically set a bolus dose of the integrated hand-held medicament injection pen, whereby the user can manually inject the bolus dose of medicament into the host. In some embodiments, the integrated receiver and hand-held medicament injection pen are integrally formed, while in other embodiments they are detachably connected and communicated via mutually engaging electrical contacts and/or via wireless communication.

What is claimed is: 
     
         1 . A method for monitoring and treating diabetes, comprising:
 administering an amount of a medicament into a host;   receiving and processing sensor data from a continuous glucose sensor, wherein the sensor data is indicative of a glucose concentration of the host in vivo; and   inputting host information to a user interface, outputting the sensor data on the user interface, or outputting medicament therapy on the user interface.   
     
     
         2 . The method of  claim 1  wherein the administering is selected from the group consisting of injecting, infusing, causing inhalation or transdermal absorption of the amount of medicament into the host. 
     
     
         3 . The method of  claim 1  further comprising calculating at least one of a time of medicament therapy and an amount of medicament therapy. 
     
     
         4 . The method of  claim 1  further comprising displaying a graphical representation of at least one of sensor data and medicament delivery data, wherein a solid line represents at least one of a target glucose concentration and a range. 
     
     
         5 . The method of  claim 1  wherein the administering is performed by a medicament injection pen or a medicament pump. 
     
     
         6 . The method of  claim 1  wherein the administering is performed by a medicament injection pen and further comprising remotely controlling a rate of medicament injection by the medicament injection pen into the host. 
     
     
         7 . The method of  claim 1  further comprising requiring validation prior to administering the amount of the medicament into the host. 
     
     
         8 . The method of  claim 1  wherein processing the sensor data includes processing the sensor data and generating the medicament therapy. 
     
     
         9 . A method for monitoring and treating diabetes, comprising:
 administering an amount of a medicament into a host;   receiving and processing sensor data from a continuous glucose sensor, wherein the sensor data is indicative of a glucose concentration of the host in vivo; and   requiring validation prior to administering the amount of the medicament into the host.   
     
     
         10 . The method of  claim 9  further comprising inputting host information to a user interface, outputting the sensor data on the user interface, or outputting medicament therapy on the user interface. 
     
     
         11 . The method of  claim 9  wherein the administering is selected from the group consisting of injecting, infusing, causing inhalation or transdermal absorption of the amount of medicament into the host. 
     
     
         12 . The method of  claim 9  further comprising calculating at least one of a time of medicament therapy and an amount of medicament therapy. 
     
     
         13 . The method of  claim 9  further comprising displaying a graphical representation of at least one of sensor data and medicament delivery data, wherein a solid line represents at least one of a target glucose concentration and a range. 
     
     
         14 . The method of  claim 9  wherein the administering is performed by a medicament injection pen or a medicament pump. 
     
     
         15 . The method of  claim 9  wherein the administering is performed by a medicament injection pen and further comprising remotely controlling a rate of medicament injection by the medicament injection pen into the host. 
     
     
         16 . The method of  claim 10  wherein processing the sensor data includes processing the sensor data and generating the medicament therapy.