Methods for treating and preventing nociceptive pain

Abstract

Methods of treating a condition resulting in nociceptive pain are provided. The method includes the step of administering to a mammal a therapeutically effective amount of a compound selected from the group consisting of diacetyl salicylic acid (DAS), aurin tricarboxylic acid (ATA), aurin quadracarboxylic acid (AQA), aurin hexacarboxylic acid (AHA), and/or a combination thereof.

1 . A method of treating a condition resulting in nociceptive pain by administering to a mammal a therapeutically effective amount of a compound selected from the group consisting of diacetyl salicylic acid (DAS), aurin tricarboxylic acid (ATA), aurin quadracarboxylic acid (AQA), aurin hexacarboxylic acid (AHA), and a combination thereof. 
     
     
         2 . A method according to  claim 1  wherein the compound comprises DAS. 
     
     
         3 . A method according to  claim 1  wherein the compound comprises ATA. 
     
     
         4 . A method according to  claim 1  wherein the compound comprises AQA. 
     
     
         5 . A method according to  claim 1  wherein the compound comprises AHA. 
     
     
         6 . A method according to  claim 1  wherein the compound comprises a combination of DAS, ATA, AQA, and/or AHA. 
     
     
         7 . A method according to  claim 1  wherein the condition is thermal burn. 
     
     
         8 . A method according to  claim 1  wherein the condition is surgical trauma. 
     
     
         9 . A method according to  claim 1  wherein the condition is post-operative pain. 
     
     
         10 . A method according to  claim 1  wherein the condition is an ultraviolet burn. 
     
     
         11 . A method according to  claim 1  wherein the compound is a formulated in a skin care preparation at a concentration of 0.001 to 1 mg/mL. 
     
     
         12 . A method according to  claim 11  wherein the skin care preparation is formulated as a spray, gel, cream, lotion, stick, ointment, scrub, soap bar, tonic, roll-on formulation, sunscreen, shampoo or mousse. 
     
     
         13 . A method according to  claim 1  wherein the compound is a formulated in a pharmaceutical composition at a concentration of 0.001 to 1 mg/mL. 
     
     
         14 . A method according to  claim 13  wherein the pharmaceutical composition comprises a solution suitable for intradermal or subcutaneous administration.