US2021244345A1PendingUtilityA1

Non-invasive system for calculating a human or animal, reliable, standardized and complete score

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Assignee: ECHOSENSPriority: Aug 2, 2013Filed: Apr 26, 2021Published: Aug 12, 2021
Est. expiryAug 2, 2033(~7.1 yrs left)· nominal 20-yr term from priority
G16B 99/00G16H 50/30C12Q 2600/156A61B 8/485A61B 5/4869G01N 33/6893A61B 8/5223C12Q 1/6883A61B 5/4244G01N 33/483
61
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Claims

Abstract

A non-invasive system for calculating a human or animal score, the system including a measurement slave device constructed and arranged to carry out measurements of biological parameters; a measure slave device constructed and arranged to carry out measurements of physical parameters; a master device constructed and arranged to collect the biological and physical parameters and calculate the human or animal score, the score including biological and physical parameters.

Claims

exact text as granted — not AI-modified
1 .- 24 . (canceled) 
     
     
         25 . A method for calculating a human or animal score, said method comprising:
 carrying out measurements of one or more blood parameters of a patient with a blood chemical analyzer;   carrying out measurements of one or more physical parameters of the patient with an elastography apparatus, the one or more physical parameters comprising at least one of elasticity, stiffness, viscosity, ultrasound attenuation, or shear wave speed, associated with biological tissues, the elastography apparatus including an ultrasonic transducer configured to emit ultrasound shots and to receive corresponding echo signals to track how biological tissues of the patient are moved by a shear wave generated by the elastography apparatus, wherein the measurements of the one or more blood parameters and the measurements of the one or more physical parameters are carried out concurrently or within a same time frame;   collecting by a master device said one or more blood parameters and at least one of said physical parameters, the master device including a processor and a computer-readable medium having machine-executable instructions to, when executed by the processor, calculate said human or animal score on the basis of the measurements of the one or more blood parameters and the at least one of said physical parameters.   
     
     
         26 . The method according to  claim 25 , wherein the blood chemical analyzer is directly operatively connected to the elastography apparatus by a wired connection, an infrared link or a wireless link. 
     
     
         27 . The method according to  claim 25 , wherein the master device is a server. 
     
     
         28 . The method according to  claim 25 , further comprising inputting via an interface said one or more blood parameters and the at least one of said physical parameters so that the master device collects said one or more blood parameters and the at least one of said physical parameters. 
     
     
         29 . The method according to  claim 28 , wherein the interface is a keyboard. 
     
     
         30 . The method according to  claim 25 , further comprising displaying on a display screen said human or animal score. 
     
     
         31 . The method according to  claim 25 , wherein the one or more blood parameters are selected from the group consisting of:
 albumin,   alkaline phosphastase,   aspartate aminotransferase,   alanine aminotransferase,   amylase,   bilirubin,   blood urea nitrogen,   calcium,   creatine kinase,   chloride,   creatinine,   c-reactive protein,   gamma glutamyl,   transpeptidase,   glucose,   potassium,   magnesium,   sodium,   phosphorus,   total carbon dioxyde,   total protein,   uric acid,   total cholesterol,   high density lipoprotein,   triglycerides,   hyaluronic acid,   alpha 2 macroglobulin, and any combination thereof.   
     
     
         32 . The method according to  claim 31 , wherein the one or more blood parameters are selected from the group consisting of:
 aspartate aminotransferase,   hyaluronic acid,   alanine aminotransferase,   bilirubin,   alpha 2 macroglobulin,   gamma glutamyl   transpeptidase and any combination thereof.   
     
     
         33 . The method according to  claim 25 , wherein the one or more blood parameters are one or more hematology parameters selected from the group consisting of:
 platelet,   white blood cell,   red blood cell,   prothrombin index,   INR, and any combination thereof.   
     
     
         34 . The method according to  claim 25 , wherein the one or more blood parameters are selected from the group consisting of:
 platelet,   prothrombin index,   INR, and any combination thereof.   
     
     
         35 . The method according to  claim 25 , wherein the blood chemical analyzer is an in-vitro analyzer. 
     
     
         36 . The method according to  claim 35 , wherein the in-vitro analyzer is a DNA-based test analyzer. 
     
     
         37 . The method according to  claim 35 , wherein the in-vitro analyzer is an immunology test analyzer. 
     
     
         38 . The method according to  claim 37 , wherein the immunology test analyzer is configured to measure one or more genetic makers selected from the group consisting of:
 Albumin,   Bilirubin,   CRP,   Ferritin,   Alpha 2 macroglobulin,   Hyaluronic acid,   Laminin,   Apolipoprotein A1,   Haptoglobin,   PIIINP,   TIMP-1,   MMPs,   Adiponectin,   IL-6,   Alpha Fetoprotein,   CK18,   Chemokine ligand 2,   TNF alpha,   HbA1c,   anti-HCV,   HBsAg,   HBsAb,   HbeAg,   HbeAb,   HbcAb and any combination thereof.   
     
     
         39 . The method according to  claim 25 , wherein the one or more physical parameters include the stiffness or the ultrasound attenuation associated with the biological tissues. 
     
     
         40 . The method according to  claim 25 , wherein the master device is configured to collect said one or more blood parameters and the at least one of said physical parameters from a point of care testing. 
     
     
         41 . The method according to  claim 25 , wherein the computer-readable medium of the master device includes machine-executable instructions to, when executed by the processor, automatically collect said one or more blood parameters and the at least one of said physical parameters. 
     
     
         42 . The method according to  claim 25 , wherein the computer-readable medium of the master device includes machine-executable instructions to, when executed by the processor, carry out the measurements of said one or more blood parameters via the blood chemical analyzer and of said at least one of said physical parameters via the elastography apparatus.

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