Agent For Conditioning Dentin And Enamel

Abstract

Aqueous solution of a transition and main group metal salt for use as conditioning agent in dental restoration therapy and method of conditioning a tooth surface.

1 . A method of conditioning a tooth surface comprising
 applying an aqueous solution comprising one or more transition and/or main group metal salts to the tooth surface.   
     
     
         2 . The method according to  claim 1  comprising
 applying the aqueous solution before the application of dental cements, filling composites, coating materials or veneering materials, in the conditioning of the tooth surface in dental restoration therapy, in the restoration of damaged teeth, or in restorative filling therapy, or before securing of fixed prosthodontics by adhesive cementing, in preventive measures such as the sealing of tooth fissures, or in orthodontic measures such as the securing of brackets. 
 
     
     
         3 . The method according to  claim 1 ,
 wherein the step of applying the aqueous solution etches the tooth surface or inactivates a matrix metalloproteinase(s) and/or cysteine cathepsin(s)on the tooth surface.   
     
     
         4 . A method of pre-treating a surface of a dental restoration comprising,
 applying an aqueous solution comprising one or more transition and/or main group metal salts extraorally to the surface of the dental restoration,   wherein the dental restoration comprises prostheses, artificial teeth, inlays, onlays, crowns and bridges.   
     
     
         5 . The method according to  claim 1 ,
 wherein the one or more transition and/or main group metal salts are salts of a metal of group 4 and/or of main group 14 or 15 of the periodic table of elements.   
     
     
         6 . The method according to  claim 1 ,
 wherein the transition and/or main group metal salt is a salt of a trivalent or tetravalent metal ion.   
     
     
         7 . The method according to  claim 6 ,
 wherein the metal ion is Zr 4+ , Hf 4+ , Ti 4+ , Bi 3+  or Sn 4+ .   
     
     
         8 . The method according to  claim 1 ,
 wherein the transition or main group metal salt comprises as anion Cl − , Br − , I − , NO 3− , SO 4   2− , optionally as mixed salts with oxoanions.   
     
     
         9 . The method according to  claim 1 ,
 wherein the transition and/or main group metal salt comprises ZrOCl 2 , ZrO(NO 3 ) 2 , Zr(SO 4 ) 2 , Hf(SO 4 ) 2 , HfCl 4 , Hf(NO 3 ) 4 , TiOSO 4 , Bi(NO 3 ) 3 , SnCl 4  or a mixture of these salts.   
     
     
         10 . The method according to  claim 1 ,
 wherein the aqueous solution additionally comprises a further metal salt which is selected from the salts of Cu 2+ , Zn 2+ , Al 3+  and mixtures thereof.   
     
     
         11 . The method according to  claim 10 ,
 wherein the further metal salt is selected from Al(NO 3 ) 3 , CuSO 4 , ZnSO 4  or a mixture thereof.   
     
     
         12 . The method according to  claim 7 ,
 wherein the metal ion is Zr 4+ , Hf 4+ , Ti 4+ or Bi 3+ .   
     
     
         13 . The method according to  claim 12 ,
 wherein the transition or main group metal salt comprises as anion Cl − , Br − , I − , NO 3   − , SO 4   2 , optionally as mixed salts with oxoanions.   
     
     
         14 . The method according to  claim 12 ,
 wherein the transition and/or main group metal salt comprises ZrOCl 2 , ZrO(NO 3 ) 2 , Zr(SO 4 ) 2 , Hf(SO 4 ) 2 , HfCl 4 , Hf(NO 3 ) 4 , TiOSO 4 , Bi(NO 3 ) 3  or a mixture of these salts.   
     
     
         15 . The method according to  claim 12 ,
 wherein the aqueous solution additionally comprises a further metal salt which is selected from the salts of Cu 2+ , Zn 2+ , Al 3+ , Sn 4+  and mixtures thereof.   
     
     
         16 . The method according to  claim 12 ,
 wherein the aqueous solution comprises as a further metal salt Al(NO 3 ) 3 , CuSO 4 , ZnSO 4 , SnCl 4  or a mixture thereof.   
     
     
         17 . The method according to  claim 1 ,
 wherein the aqueous solution contains no added acid.   
     
     
         18 . The method according to  claim 1 ,
 wherein the aqueous solution comprises 0.5 to 25 wt.-% transition and/or main group metal salt(s).   
     
     
         19 . The method according to  claim 1 ,
 wherein the aqueous solution comprises 2 to 15 wt.-% transition and/or main group metal salt, 36 to 98 wt.-% water and 0 to 49 wt.-% organic solvent, or 4 to 10 wt.-% transition and/or main group metal salt, 42 to 96 wt.-% water and 0 to 48 wt.-% organic solvent.   
     
     
         20 . The method according to  claim 1 ,
 wherein the aqueous solution comprises as organic solvent glycerol, ethanol, ethylene glycol, propylene glycol, propanediol, butanediol and polyethylene glycol or a mixture thereof.