US2021246344A1PendingUtilityA1
Biological buffers with wide buffering ranges
Est. expiryApr 17, 2028(~1.8 yrs left)· nominal 20-yr term from priority
Inventors:Thomas Daly
C07C 217/08C07D 213/74C07F 9/3808C07C 219/06C07C 219/22C07C 229/22C07C 215/10C07C 215/08C07C 229/12C07F 9/3817C07C 309/14C07F 9/091C11D 1/66C07F 9/58C07C 217/28C07C 205/40C09K 3/00C07C 205/15C07D 295/15C07D 295/088C07C 217/48
72
PatentIndex Score
0
Cited by
0
References
0
Claims
Abstract
Amines and amine derivatives that improve the buffering range, and/or reduce the chelation and other negative interactions of the buffer and the system to be buffered. The reaction of amines or polyamines with various molecules to form polyamines with differing pKa's will extend the buffering range. Derivatives that result in polyamines that have the same pKa yield a greater buffering capacity. Derivatives that result in zwitterionic buffers improve yield by allowing a greater range of stability.
Claims
exact text as granted — not AI-modified1 . A biological buffer of the following structure:
where D, E and G are the same or different and chosen from the group containing H, —CH 3 , —CH 2 OH, —CH 2 CH 3 and M and L are the same or different and chosen from the group —H, —CH 3 , —CH 2 OH, —CH 2 CH 2 OH, —C(CH 2 OH) 3 , —C(CH 3 ) 2 CH 2 OH.
2 . The buffer of claim 1 where D=E=G=—CH 2 OH and M=L=—CH 3 .
3 . The buffer of claim 1 where D=E=G=—CH 2 OH and M=L=—CH 2 CH 2 OH.
4 . The buffer of claim 1 where D=—CH 2 OH, and E=G=—CH 3 and M=L=—CH 3 .
5 . The buffer of claim 1 where D=—CH 2 OH, and E=G=—CH 3 and M=L=—CH 2 CH 2 OH.
6 . The buffer of claim 1 where D=—CH 2 OH, E=G=—CH 3 , M═—H and L=—C(CH 3 ) 2 CH 2 OH.
7 . The buffer of claim 1 where D=E=G=—CH 2 OH, M=—H and L=-C(CH 2 OH) 3 .
8 . The biological buffer of the following structure:
where D, D′,E,E′ are the same or different and chosen from the group containing H, —CH 3 , —CH 2 OH, —CH 2 CH 3 .
9 . The buffer of claim 8 where D=D′=E=E′=—CH 2 OH.
10 . The buffer of claim 8 where D=D′=E=E′=—CH 3 .
11 . The buffer of claim 8 where D=D′=—CH 3 , E=E′=—CH 2 OH.
12 . The buffer of claim 8 where D=D′=—CH 2 CH 3 , E=-H, E′=—CH 2 OH.
13 . The quaternary ammonium compound and its salts of the following structure:
where A, D, and E are independently chosen from, —H, —CH 3 , —CH 2 CH 3 , —CH 2 OH; G is chosen from —H, or —CH 2 CH 3 ; R and R′ are chosen independently and selected from the group alkyl, alkenal, or alkynal, linear or branched, saturated or unsaturated.
14 . The quaternary ammonium compound and its salts of claim 13 wherein A=D=—CH 3 , E=—CH 2 OH, R═R′=—CH 3 and G=-H.
15 . The quaternary ammonium compound and its salts of claim 13 wherein A=D=E=—CH 2 OH, R═R′=—CH 3 and G=-H.
16 . The quaternary ammonium compound and its salts of claim 13 wherein A=D=—CH 3 , E=—CH 2 OH, R═R′=—CH 3 and G=—CH 2 CH 3 .
17 . The quaternary ammonium compound and its salts of claim 13 wherein A=D=E=—CH 2 OH, R═R′=—CH 3 and G=—CH 2 CH 3 .Join the waitlist — get patent alerts
Track US2021246344A1 — get alerts on status changes and closely related new filings.
We store only your email — no account needed. See our privacy policy.