Cannabis oil compositions and methods for preparation thereof

Abstract

The present invention provides cannabis oil compositions, including cannabis oil compositions containing vitamin E, and methods for preparing the cannabis oil compositions. In some embodiments, the invention provides a method for preparing a cannabis oil composition comprising eluting cannabinoids from cannabis plant material with a solvent to produce an eluate; filtering the eluate with a filter to produce a filtrate; evaporating the solvent from the filtrate with a distiller to produce a distillate; and purging the distillate under conditions sufficient to remove residual solvent. In some embodiments, the method further includes mixing a quantity of vitamin E with the extract. Blended cannabis oil compositions containing mixtures of cannabis oil preparations are also described.

1 . A composition comprising a first cannabis oil preparation having a first cannabinoid profile and a second cannabis oil preparation having a second cannabinoid profile. 
     
     
         2 . The composition of  claim 1 , wherein the composition comprises Δ 9 -tetrahydrocannabinol (THC) and (−)-cannabidiol (CBD). 
     
     
         3 . The composition of  claim 2 , wherein the ratio of THC to CBD ranges from about 30:1 to about 1:30 by weight. 
     
     
         4 . The composition of  claim 3 , wherein the ratio of THC to CBD is about 4:1 by weight, or about 1:1 by weight, or about 1:2 by weight: or about 1:20 by weight. 
     
     
         5 - 7 . (canceled) 
     
     
         8 . The composition of  claim 2 , wherein greater than 50% of the total THC in the composition is present in the first cannabinoid profile, and greater than 50% of the total CBD in the composition is present in the second cannabinoid profile. 
     
     
         9 . (canceled) 
     
     
         10 . The composition of  claim 2 , further comprising a third cannabis oil preparation having a third cannabinoid profile. 
     
     
         11 . The composition of  claim 10 , further comprising a fourth cannabis oil preparation having a fourth cannabinoid profile. 
     
     
         12 . The composition of  claim 11 , wherein
 at least 50% of the total THC in the composition is present in the combined cannabinoid profile of the first cannabis oil preparation, the second cannabis oil preparation, and the third cannabis oil preparation, and   at least 50% of the total CBD in the composition is present in the fourth cannabinoid profile.   
     
     
         13 . (canceled) 
     
     
         14 . The composition of  claim 2 , further comprising Δ 9 -tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBDA), or a combination thereof. 
     
     
         15 . The composition of  claim 2 , further comprising one or more cannabinoids selected from the group consisting of cannabigerol (CBG), cannibinol (CBN), and cannabigerolic acid (CBGA). 
     
     
         16 . The composition of  claim 1 , wherein the first cannabis oil preparation is prepared from the AC/DC cannabis strain, and wherein the second cannabis oil preparation is prepared from a  Cannabis sativa  strain. 
     
     
         17 . The composition of  claim 16 , wherein the ratio of the first cannabis oil preparation to the second cannabis oil preparation is about 1:1 by weight. 
     
     
         18 . The composition of  claim 1 , wherein the first cannabis oil preparation is prepared from the Medihaze cannabis strain, and wherein the second cannabis oil preparation is prepared from a  Cannabis indica  strain. 
     
     
         19 . The composition of  claim 18 , wherein the ratio of the first cannabis oil preparation to the second cannabis oil preparation is about 1:1 by weight. 
     
     
         20 . The composition of  claim 16 , further comprising one or more essential oils selected from the group consisting of bergamot essential oil, blood orange essential oil, neroli essential oil, lemon essential oil, peppermint essential oil, and spearmint essential oil. 
     
     
         21 . The composition of  claim 16 , further comprising one or more essential oils selected from the group consisting of Sweet Orange ( Citrus sinensis  spp), Peppermint ( Mentha piperita  spp), Lemon ( Citrus limon  spp), Lavender ( Lavendula angustifolia  spp) and Vanilla ( Vanilla planifolia  spp). 
     
     
         22 . The composition of  claim 16 , further comprising one or more essential oils selected from lavender essential oil and lemongrass essential oil. 
     
     
         23 . The composition of  claim 16 , further comprising vanilla essential oil. 
     
     
         24 . (canceled) 
     
     
         25 . The composition of  claim 11 , wherein the first cannabis oil preparation is prepared from a  Cannabis indica  strain, the second cannabis oil preparation is prepared from a  Cannabis sativa  strain, the third cannabis oil preparation is prepared from the Blueberry cannabis strain, and the fourth cannabis oil preparation is prepared from the AC/DC cannabis strain. 
     
     
         26 . The composition of  claim 25 , where the ratio of the first, second, third, and fourth cannabis oil preparations is about 55:10:10:25 by weight. 
     
     
         27 . (canceled) 
     
     
         28 . A method for treating cancer, the method comprising administering a composition according to  claim 1  to a subject in need thereof.