Bioabsorbable polymeric composition for a medical device

Abstract

A crystallized bioabsorbable polymer scaffold comprises a polymer composition of poly (L-lactide-co-tri-methylene-carbonate) or poly (D-lactide-co-tri-methylene-carbonate) or poly (L-lactide-co-ε-caprolactone) or poly (D-lactide-co-ε-caprolactone) in the form of block copolymers of blocky copolymers, wherein the scaffold is cold-bendable.

What is claimed is: 
     
         1 . A crystallized bioabsorbable polymer scaffold comprising a polymer composition of poly (L-lactide-co-tri-methylene-carbonate) or poly (D-lactide-co-tri-methylene-carbonate) or poly (L-lactide-co-ε-caprolactone) or poly (D-lactide-co-ε-caprolactone) in the form of block copolymers of blocky copolymers, wherein the scaffold is cold-bendable. 
     
     
         2 . The bioabsorbable polymer scaffold of  claim 1 , wherein the scaffold is cold bendable at temperatures in a range of about 10° C. to about 30° C. 
     
     
         3 . The bioabsorbable polymer scaffold of  claim 1 , wherein the polymer composition comprises poly (L-lactide-co-ε-caprolactone) or poly (D-lactide-co-ε-caprolactone). 
     
     
         4 . The bioabsorbable polymer scaffold of  claim 1 , wherein the polymer composition comprises poly (L-lactide-co-ε-caprolactone). 
     
     
         5 . The bioabsorbable polymer scaffold of  claim 1 , further comprising a poly (L-lactide) moiety or a poly (D-lactide) moiety or a poly L-lactide-co-PEG moiety or a poly D-lactide-co-PEG moiety. 
     
     
         6 . The bioabsorbable polymer scaffold of  claim 1 , wherein the composition includes increased hydrophilicity and free molecular volume allowing for uptake of water. 
     
     
         7 . The bioabsorbable polymer scaffold of  claim 1 , wherein the composition includes amorphous and semicrystalline polymer portions. 
     
     
         8 . The bioabsorbable polymer scaffold of  claim 7 , wherein a crystallinity and tensile strength of the composition is adjustable by elongation of the semicrystalline portion. 
     
     
         9 . The bioabsorbable polymer scaffold of  claim 1 , further comprising at least one radiopaque marker. 
     
     
         10 . A crystallized bioabsorbable polymer scaffold comprising a polymer composition of poly (L-lactide-co-tri-methylene-carbonate) or poly (D-lactide-co-tri-methylene-carbonate) or poly (L-lactide-co-ε-caprolactone) or poly (D-lactide-co-ε-caprolactone) in the form of block copolymers of blocky copolymers, wherein the scaffold crystallizes in response to orthogonal strain. 
     
     
         11 . The bioabsorbable polymer scaffold of  claim 10 , wherein the scaffold includes struts that orient and crystallize in response to orthogonal strain upon deployment. 
     
     
         12 . The bioabsorbable polymer scaffold of  claim 10 , wherein the polymer composition comprises poly (L-lactide-co-ε-caprolactone) or poly (D-lactide-co-ε-caprolactone). 
     
     
         13 . The bioabsorbable polymer scaffold of  claim 10 , wherein the polymer composition comprises poly (L-lactide-co-ε-caprolactone). 
     
     
         14 . The bioabsorbable polymer scaffold of  claim 10 , further comprising a poly (L-lactide) moiety or a poly (D-lactide) moiety or a poly L-lactide-co-PEG moiety or a poly D-lactide-co-PEG moiety. 
     
     
         15 . The bioabsorbable polymer scaffold of  claim 10 , wherein the composition includes increased hydrophilicity and free molecular volume allowing for uptake of water. 
     
     
         16 . The bioabsorbable polymer scaffold of  claim 10 , wherein the composition includes amorphous and semicrystalline polymer portions. 
     
     
         17 . The bioabsorbable polymer scaffold of  claim 10 , further comprising at least one radiopaque marker. 
     
     
         18 . A crystallized bioabsorbable polymer scaffold comprising a polymer composition of poly (L-lactide-co-tri-methylene-carbonate) or poly (D-lactide-co-tri-methylene-carbonate) or poly (L-lactide-co-ε-caprolactone) or poly (D-lactide-co-ε-caprolactone) wherein a contaminant monomeric residual fraction in the scaffold does not exceed about 0.5%. 
     
     
         19 . The bioabsorbable polymer scaffold of  claim 18 , wherein contaminant monomeric residual fraction in the scaffold does not exceed about 0.3%. 
     
     
         20 . The bioabsorbable polymer scaffold of  claim 18 , wherein contaminant monomeric residual fraction in the scaffold does not exceed about 0.2%. 
     
     
         21 . The bioabsorbable polymer scaffold of  claim 18 , wherein the polymer composition comprises poly (L-lactide-co-ε-caprolactone) or poly (D-lactide-co-ε-caprolactone). 
     
     
         22 . The bioabsorbable polymer scaffold of  claim 18 , wherein the polymer composition comprises poly (L-lactide-co-ε-caprolactone). 
     
     
         23 . The bioabsorbable polymer scaffold of  claim 18 , further comprising a poly (L-lactide) moiety or a poly (D-lactide) moiety or a poly L-lactide-co-PEG moiety or a poly D-lactide-co-PEG moiety. 
     
     
         24 . The bioabsorbable polymer scaffold of  claim 18 , wherein the composition includes increased hydrophilicity and free molecular volume allowing for uptake of water. 
     
     
         25 . The bioabsorbable polymer scaffold of  claim 18 , wherein the composition includes amorphous and semicrystalline polymer portions. 
     
     
         26 . The bioabsorbable polymer scaffold of  claim 25 , wherein a crystallinity and tensile strength of the composition is adjustable by elongation of the semicrystalline portion. 
     
     
         27 . The bioabsorbable polymer scaffold of  claim 18 , further comprising at least one radiopaque marker.