Medical devices having homogeneous charge density and methods for making same

Abstract

The present invention relates to ionic silicone hydrogel polymers displaying improved lysozyme uptake, low contact angle and reduced water soluble polymeric ammonium salt uptake.

1 - 36 . (canceled) 
     
     
         37 . A silicone hydrogel contact lens comprising between about 50 ppm and about 1 wt % of at least one uncrosslinked statistical copolymer comprising at least about 10 weight % of at least one non-ionic hydrophilic monomer and at least about 20 mol % of at least one anionic repeating unit distributed randomly throughout said polymer, wherein the contact lens is comprised of a silicone hydrogel polymer containing units derived from N-vinyl pyrrolidone. 
     
     
         38 . The contact lens of  claim 37  wherein said copolymer is present in an amount between about 20 ppm and 2000 ppm. 
     
     
         39 . The contact lens of  claim 37  wherein said copolymer is present in an amount between about 50 ppm and 1500 ppm. 
     
     
         40 - 42 . (canceled) 
     
     
         43 . The contact hydrogel of  claim 37  wherein the silicone hydrogel polymer further contains units derived from a monomethacryloxypropyl terminated mono-n-butyl terminated polydimethylsiloxane.