Fluid chromatography injectors and injector inserts

Abstract

Certain embodiments described herein are directed to injector inserts and injector assemblies. In some examples, an injector insert that includes an inlet comprising a substantially inert metal is described. In other examples, an injector that includes a major amount of a substantially inert metal in a fluid flow path is disclosed. Devices and systems using the injectors inserts and injectors are also described.

What is claimed is: 
     
         1 . A fluid injector insert comprising an inlet and an outlet, in which the insert is constructed and arranged to couple to an injector assembly to fluidically couple the inlet of the insert to a fluid flow path of the injector assembly, in which the inlet of the insert comprises a substantially inert metal material. 
     
     
         2 . The fluid injector insert of  claim 1 , in which the substantially inert metal material is present in a major amount. 
     
     
         3 . The fluid injector insert of  claim 1 , in which the substantially inert metal material comprises titanium, aluminum, yttrium or combinations thereof. 
     
     
         4 . The fluid injector insert of  claim 3 , in which the substantially inert metal material comprises titanium oxide, aluminum oxide, yttrium oxide or combinations thereof. 
     
     
         5 . The fluid injector insert of  claim 1 , in which the substantially inert metal material comprises nickel. 
     
     
         6 . The fluid injector insert of  claim 5 , in which the substantially inert metal material is a Hastelloy® alloy. 
     
     
         7 . The fluid injector insert of  claim 1 , in which the substantially inert metal material comprises chromium. 
     
     
         8 . The fluid injector insert of  claim 7 , in which the substantially inert metal material is an Inconel® alloy. 
     
     
         9 . The fluid injector insert of  claim 1 , in which the inlet and the outlet each comprises a substantially inert metal material. 
     
     
         10 . The fluid injector insert of  claim 9 , in which the substantially inert metal material of the inlet and the outlet are the same material. 
     
     
         11 . A fluid injector insert comprising an inlet and an outlet, in which the insert is constructed and arranged to couple to an injector assembly to fluidically couple the inlet to a fluid flow path of the injector assembly, in which the inlet of the insert comprises a non-catalytic metal material present in an effective amount to deter catalysis by the inlet. 
     
     
         12 . The fluid injector insert of  claim 1 , in which the non-catalytic metal material is present in a major amount. 
     
     
         13 . The fluid injector insert of  claim 11 , in which the non-catalytic metal material comprises titanium, aluminum, yttrium or combinations thereof. 
     
     
         14 . The fluid injector insert of  claim 13 , in which the non-catalytic metal material comprises titanium oxide, aluminum oxide, yttrium oxide or combinations thereof. 
     
     
         15 . The fluid injector insert of  claim 11 , in which the non-catalytic metal material comprises nickel. 
     
     
         16 . The fluid injector insert of  claim 15 , in which the non-catalytic metal material is a Hastelloy® alloy. 
     
     
         17 . The fluid injector insert of  claim 11 , in which the non-catalytic metal material comprises chromium. 
     
     
         18 . The fluid injector insert of  claim 17 , in which the non-catalytic metal material is an Inconel® alloy. 
     
     
         19 . The fluid injector insert of  claim 11 , in which the inlet and the outlet each comprises a non-catalytic metal material. 
     
     
         20 . The fluid injector insert of  claim 19 , in which the non-catalytic metal material of the inlet and the outlet are the same material. 
     
     
         21 . A fluid injector comprising an inlet and an outlet, the fluid injector further comprising a fluid flow path fluidically coupled to the inlet, in which the inlet and the outlet are configured to receive a chromatography column, and in which the inlet comprises a non-catalytic metal material present in an major amount to deter catalysis by the inlet. 
     
     
         22 . The fluid injector of  claim 21 , in which the non-catalytic metal material comprises titanium, aluminum, yttrium or combinations thereof. 
     
     
         23 . The fluid injector of  claim 22 , in which the non-catalytic metal material comprises titanium oxide, aluminum oxide, yttrium oxide or combinations thereof. 
     
     
         24 . The fluid injector of  claim 21 , in which the non-catalytic metal material comprises nickel. 
     
     
         25 . The fluid injector of  claim 25 , in which the non-catalytic metal material is a Hastelloy® alloy. 
     
     
         26 . The fluid injector of  claim 21 , in which the non-catalytic metal material comprises chromium. 
     
     
         27 . The fluid injector of  claim 27 , in which the non-catalytic metal material is an Inconel® alloy. 
     
     
         28 . The fluid injector of  claim 21 , in which the inlet and the outlet each comprises a non-catalytic metal material present in an effective amount to deter catalysis. 
     
     
         29 . The fluid injector of  claim 28 , in which the non-catalytic material of the inlet and the outlet are the same material. 
     
     
         30 . The fluid injector of  claim 28 , in which the non-catalytic material of the inlet and the outlet are a different material. 
     
     
         31 . A fluid injector comprising an inlet and an outlet, the fluid injector further comprising a fluid flow path fluidically coupled to the inlet, in which the inlet and the outlet are configured to receive a chromatography column, and in which the inlet comprises a major amount of a substantially inert metal material. 
     
     
         32 . The fluid injector of  claim 31 , in which the substantially inert metal material comprises titanium, aluminum, yttrium or combinations thereof. 
     
     
         33 . The fluid injector of  claim 32 , in which the substantially inert metal material comprises titanium oxide, aluminum oxide, yttrium oxide or combinations thereof. 
     
     
         34 . The fluid injector of  claim 31 , in which the substantially inert metal material comprises nickel. 
     
     
         35 . The fluid injector of  claim 34 , in which the substantially inert metal material is a Hastelloy® alloy. 
     
     
         36 . The fluid injector of  claim 31 , in which the substantially inert metal material comprises chromium. 
     
     
         37 . The fluid injector of  claim 36 , in which the substantially inert metal material is an Inconel® alloy. 
     
     
         38 . The fluid injector of  claim 31 , in which the inlet and the outlet each comprises a major amount of a substantially inert metal material. 
     
     
         39 . The fluid injector of  claim 38 , in which the substantially inert metal material of the inlet and the outlet are the same material. 
     
     
         40 . The fluid injector of  claim 38 , in which the substantially inert metal material of the inlet and the outlet are a different material. 
     
     
         41 . A fluid injector insert comprising an inlet and an outlet, in which the inlet comprises a non-catalytic, non-glass material present in an effective amount to deter catalysis by the inlet. 
     
     
         42 . The fluid injector insert of  claim 41 , in which the non-catalytic, non-glass material comprises titanium, aluminum, yttrium or combinations thereof. 
     
     
         43 . The fluid injector insert of  claim 42 , in which the non-catalytic, non-glass material comprises titanium oxide, aluminum oxide, yttrium oxide or combinations thereof. 
     
     
         44 . The fluid injector insert of  claim 41 , in which the non-catalytic, non-glass material comprises nickel. 
     
     
         45 . The fluid injector insert of  claim 44 , in which the non-catalytic, non-glass material is a Hastelloy® alloy. 
     
     
         46 . The fluid injector insert of  claim 41 , in which the non-catalytic, non-glass material comprises chromium. 
     
     
         47 . The fluid injector insert of  claim 46 , in which the non-catalytic, non-glass material is an Inconel® alloy. 
     
     
         48 . The fluid injector insert of  claim 41 , in which the inlet and the outlet each comprises a non-catalytic, non-glass material present in an effective amount to deter catalysis. 
     
     
         49 . The fluid injector insert of  claim 48 , in which the non-catalytic, non-glass material of the inlet and the outlet are the same material. 
     
     
         50 . The fluid injector insert of  claim 48 , in which the non-catalytic, non-glass material of the inlet and the outlet are a different material. 
     
     
         51 . A fluid injector insert comprising an inlet and an outlet, in which the inlet comprises a substantially inert non-glass, non-stainless steel material. 
     
     
         52 . The fluid injector insert of  claim 51 , in which the substantially inert non-glass, non-stainless steel material comprises titanium, aluminum, yttrium or combinations thereof. 
     
     
         53 . The fluid injector insert of  claim 52 , in which the substantially inert non-glass, non-stainless steel material comprises titanium oxide, aluminum oxide, yttrium oxide or combinations thereof. 
     
     
         54 . The fluid injector insert of  claim 51 , in which the substantially inert non-glass, non-stainless steel material comprises nickel. 
     
     
         55 . The fluid injector insert of  claim 54 , in which the substantially inert non-glass, non-stainless steel material is a Hastelloy® alloy. 
     
     
         56 . The fluid injector insert of  claim 51 , in which the substantially inert non-glass, non-stainless steel material comprises chromium. 
     
     
         57 . The fluid injector insert of  claim 56 , in which the substantially inert non-glass, non-stainless steel material is an Inconel® alloy. 
     
     
         58 . The fluid injector insert of  claim 51 , in which the inlet and the outlet each comprises a substantially inert non-glass, non-stainless steel material present in an effective amount to deter catalysis. 
     
     
         59 . The fluid injector insert of  claim 58 , in which the substantially inert non-glass, non-stainless steel material of the inlet and the outlet are the same material. 
     
     
         60 . The fluid injector insert of  claim 58 , in which the substantially inert non-glass, non-stainless steel material of the inlet and the outlet are a different material. 
     
     
         61 . A fluid injector insert comprising an inlet and an outlet, each of the inlet and the outlet comprising an internal channel coupled to each other, in which the insert is constructed and arranged to couple to an injector assembly to fluidically couple the inlet to a fluid flow path of the injector assembly, in which the inlet comprises a substantially inert metal oxide material. 
     
     
         62 . The fluid injector insert of  claim 61 , in which the substantially inert metal oxide material is present in a major amount. 
     
     
         63 . The fluid injector insert of  claim 61 , in which the substantially inert metal oxide material comprises titanium, aluminum, yttrium or combinations thereof. 
     
     
         64 . The fluid injector insert of  claim 63 , in which the substantially inert metal oxide material comprises titanium oxide, aluminum oxide, yttrium oxide or combinations thereof. 
     
     
         65 . The fluid injector insert of  claim 61 , in which the substantially inert metal oxide material comprises nickel or chromium. 
     
     
         66 . A fluid injector insert comprising an inlet and an outlet, each of the inlet and the outlet comprising an internal channel coupled to each other, in which the insert is constructed and arranged to couple to an injector assembly to fluidically couple the inlet to a fluid flow path of the injector assembly, in which the inlet comprises a non-catalytic metal oxide material present in an effective amount to deter catalysis by the inlet. 
     
     
         67 . The fluid injector insert of  claim 66 , in which the non-catalytic metal oxide material is present in a major amount. 
     
     
         68 . The fluid injector insert of  claim 66 , in which the non-catalytic metal oxide material comprises titanium, aluminum, yttrium or combinations thereof. 
     
     
         69 . The fluid injector insert of  claim 68 , in which the non-catalytic metal oxide material comprises titanium oxide, aluminum oxide, yttrium oxide or combinations thereof. 
     
     
         70 . The fluid injector insert of  claim 66 , in which the non-catalytic metal oxide material comprises nickel or chromium. 
     
     
         71 . A fluid injector comprising an inlet and an outlet, each of the inlet and the outlet comprising an internal channel coupled to each other, the fluid injector further comprising a fluid flow path fluidically coupled to the inlet, in which the inlet comprises a non-catalytic metal oxide material present in an major amount to deter catalysis. 
     
     
         72 . The fluid injector of  claim 71 , in which the non-catalytic metal oxide material is present in a major amount. 
     
     
         73 . The fluid injector of  claim 71 , in which the non-catalytic metal oxide material comprises titanium, aluminum, yttrium or combinations thereof. 
     
     
         74 . The fluid injector of  claim 73 , in which the non-catalytic metal oxide material comprises titanium oxide, aluminum oxide, yttrium oxide or combinations thereof. 
     
     
         75 . The fluid injector of  claim 71 , in which the non-catalytic metal oxide material comprises nickel or chromium. 
     
     
         76 . A fluid injector comprising an inlet and an outlet, the fluid injector further comprising a fluid flow path fluidically coupled to the inlet, in which the inlet comprises a substantially inert metal oxide material. 
     
     
         77 . The fluid injector of  claim 76 , in which the substantially inert metal oxide material is present in a major amount. 
     
     
         78 . The fluid injector of  claim 76 , in which the substantially inert metal oxide material comprises titanium, aluminum, yttrium or combinations thereof. 
     
     
         79 . The fluid injector of  claim 78 , in which the substantially inert metal oxide material comprises titanium oxide, aluminum oxide, yttrium oxide or combinations thereof. 
     
     
         80 . The fluid injector of  claim 77 , in which the substantially inert metal oxide material comprises nickel or chromium. 
     
     
         81 . An injector assembly comprising:
 an injector housing comprising a fluid flow path; and   an injector insert mated to the injector housing, the injector insert comprising an inlet and an outlet, in which the fluid flow path of the injector housing is fluidically coupled to the inlet of the injector insert, in which the inlet comprises a substantially inert metal material.   
     
     
         82 . The injector assembly of  claim 81 , in which the substantially inert metal material is present in a major amount. 
     
     
         83 . The injector assembly of  claim 81 , in which the substantially inert metal material comprises titanium, aluminum, yttrium or combinations thereof. 
     
     
         84 . The injector assembly of  claim 83 , in which the substantially inert metal material comprises titanium oxide, aluminum oxide, yttrium oxide or combinations thereof. 
     
     
         85 . The injector assembly of  claim 81 , in which the substantially inert metal material comprises nickel or chromium. 
     
     
         86 . An injector assembly comprising:
 an injector housing comprising a fluid flow path; and   an injector insert mated to the injector housing, the injector insert comprising an inlet and an outlet, in which the fluid flow path of the injector housing is fluidically coupled to the inlet of the injector insert, in which the inlet comprises a non-catalytic metal material present in an effective amount to deter catalysis by the inlet.   
     
     
         87 . The injector assembly of  claim 86 , in which the non-catalytic metal material is present in a major amount. 
     
     
         88 . The injector assembly of  claim 86 , in which the non-catalytic metal material comprises titanium, aluminum, yttrium or combinations thereof. 
     
     
         89 . The injector assembly of  claim 88 , in which the non-catalytic metal material comprises titanium oxide, aluminum oxide, yttrium oxide or combinations thereof. 
     
     
         90 . The injector assembly of  claim 86 , in which the non-catalytic metal material comprises nickel or chromium. 
     
     
         91 . An injector assembly comprising:
 an injector housing comprising a fluid flow path; and   an injector insert mated to the injector housing, the injector insert comprising an inlet and an outlet, in which the fluid flow path of the injector housing is fluidically coupled to the inlet of the injector insert, in which the inlet comprises a substantially inert metal oxide material.   
     
     
         92 . The injector assembly of  claim 91 , in which the substantially inert metal oxide material is present in a major amount. 
     
     
         93 . The injector assembly of  claim 91 , in which the substantially inert metal oxide material comprises titanium, aluminum, yttrium or combinations thereof. 
     
     
         94 . The injector assembly of  claim 93 , in which the substantially inert metal oxide material comprises titanium oxide, aluminum oxide, yttrium oxide or combinations thereof. 
     
     
         95 . The injector assembly of  claim 91 , in which the substantially inert metal oxide material comprises nickel or chromium. 
     
     
         96 . An injector assembly comprising:
 an injector housing comprising a fluid flow path; and   an injector insert mated to the injector housing, the injector insert comprising an inlet and an outlet, in which the fluid flow path of the injector housing is fluidically coupled to the inlet of the injector insert, in which the inlet comprises a non-catalytic metal oxide material present in an major amount to deter catalysis by the inlet.   
     
     
         97 . The injector assembly of  claim 96 , in which the non-catalytic metal oxide material is present in a major amount. 
     
     
         98 . The injector assembly of  claim 96 , in which the non-catalytic metal oxide material comprises titanium, aluminum, yttrium or combinations thereof. 
     
     
         99 . The injector assembly of  claim 98 , in which the non-catalytic metal oxide material comprises titanium oxide, aluminum oxide, yttrium oxide or combinations thereof. 
     
     
         100 . The injector assembly of  claim 96 , in which the non-catalytic metal oxide material comprises nickel or chromium. 
     
     
         101 . An injector assembly comprising:
 an injector housing comprising a fluid flow path; and   an injector insert mated to the injector housing, the injector insert comprising an inlet and an outlet, in which the fluid flow path of the injector housing is fluidically coupled to the inlet of the injector insert, in which the inlet comprises a non-catalytic, non-glass material present in an effective amount to deter catalysis.   
     
     
         102 . The injector assembly of  claim 101 , in which the non-catalytic, non-glass material is present in a major amount. 
     
     
         103 . The injector assembly of  claim 101 , in which the non-catalytic, non-glass material comprises titanium, aluminum, yttrium or combinations thereof. 
     
     
         104 . The injector assembly of  claim 103 , in which the non-catalytic, non-glass material comprises titanium oxide, aluminum oxide, yttrium oxide or combinations thereof. 
     
     
         105 . The injector assembly of  claim 101 , in which the non-catalytic, non-glass material comprises nickel or chromium. 
     
     
         106 . An injector assembly comprising:
 an injector housing comprising a fluid flow path; and   an injector insert coupled to the injector housing, the injector insert comprising an inlet and an outlet, in which the fluid flow path of the injector housing is fluidically coupled to the inlet of the injector insert, in which the insert comprises a substantially inert non-glass, non-stainless steel material.   
     
     
         107 . The injector assembly of  claim 106 , in which the substantially inert non-glass, non-stainless steel material is present in a major amount. 
     
     
         108 . The injector assembly of  claim 106 , in which the substantially inert non-glass, non-stainless steel material comprises titanium, aluminum, yttrium or combinations thereof. 
     
     
         109 . The injector assembly of  claim 108 , in which the substantially inert non-glass, non-stainless steel material comprises titanium oxide, aluminum oxide, yttrium oxide or combinations thereof. 
     
     
         110 . The injector assembly of  claim 101 , in which the substantially inert non-glass, non-stainless steel material comprises nickel or chromium. 
     
     
         111 . A kit comprising an injector insert constructed and arranged to couple to an injector assembly, the injector insert comprising an inlet and an outlet, in which the inlet comprises a substantially inert metal material. 
     
     
         112 . The kit of  claim 111 , further comprising the injector assembly. 
     
     
         113 . The kit of  claim 111 , further comprising an additional injector insert constructed and arranged to couple to the injector assembly, the additional injector insert comprising an inlet and an outlet, in which the inlet of the additional injector comprises a substantially inert metal material. 
     
     
         114 . The kit of  claim 113 , in which the substantially inert metal material of the inlet of the additional injector insert is different than the substantially inert metal material of the inlet of the injector insert. 
     
     
         115 . The kit of  claim 113 , further comprising a third injector insert constructed and arranged to couple to the injector assembly, the third injector insert comprising an inlet and an outlet, in which the inlet of the third injector insert comprises a substantially inert metal material. 
     
     
         116 . A kit comprising an injector insert constructed and arranged to couple to an injector assembly, the injector insert comprising an inlet and an outlet, in which the inlet comprises a non-catalytic metal material present in an effective amount to deter catalysis by the inlet. 
     
     
         117 . The kit of  claim 116 , further comprising the injector assembly. 
     
     
         118 . The kit of  claim 116 , further comprising an additional injector insert constructed and arranged to couple to the injector assembly, the additional injector insert comprising an inlet and an outlet, in which the inlet of the additional injector insert comprises a non-catalytic metal material present in an effective amount to deter catalysis by the inlet. 
     
     
         119 . The kit of  claim 118 , in which the non-catalytic metal material of the inlet of the additional injector insert is different than the non-catalytic metal material of the inlet of the injector insert. 
     
     
         120 . The kit of  claim 118 , further comprising a third injector insert constructed and arranged to couple to the injector assembly, the third injector insert comprising an inlet and an outlet, in which the inlet of the third injector insert comprises a non-catalytic metal material present in an effective amount to deter catalysis by the inlet of the third injector insert. 
     
     
         121 . A kit comprising an injector insert constructed and arranged to couple to an injector assembly, the injector insert comprising an inlet and an outlet, in which the inlet comprises a non-catalytic, non-glass material present in an effective amount to deter catalysis by the inlet. 
     
     
         122 . The kit of  claim 121 , further comprising the injector assembly. 
     
     
         123 . The kit of  claim 121 , further comprising an additional injector insert constructed and arranged to couple to the injector assembly, the additional injector insert comprising an inlet and an outlet, in which the inlet of the additional injector insert comprises a non-catalytic, non-glass material present in an effective amount to deter catalysis by the inlet. 
     
     
         124 . The kit of  claim 123 , in which the non-catalytic, non-glass material of the inlet of the additional injector insert is different than the non-catalytic, non-glass material of the inlet of the injector insert. 
     
     
         125 . The kit of  claim 123 , further comprising a third injector insert constructed and arranged to couple to the injector assembly, the third injector insert comprising an inlet and an outlet, in which the inlet of the third injector insert comprises a non-catalytic, non-glass material present in an effective amount to deter catalysis by the inlet of the third injector insert. 
     
     
         126 . A kit comprising an injector insert constructed and arranged to couple to an injector assembly, the injector insert comprising an inlet and an outlet, in which the inlet comprises a substantially inert non-glass, non-stainless steel material. 
     
     
         127 . The kit of  claim 126 , further comprising the injector assembly. 
     
     
         128 . The kit of  claim 126 , further comprising an additional injector insert constructed and arranged to couple to the injector assembly, the additional injector insert comprising an inlet and an outlet, in which the inlet of the additional injector insert comprises a substantially inert non-glass, non-stainless steel material. 
     
     
         129 . The kit of  claim 128 , in which the substantially inert non-glass, non-stainless steel material of the inlet of the additional injector insert is different than the substantially inert non-glass, non-stainless steel material of the inlet of the injector insert. 
     
     
         130 . The kit of  claim 128 , further comprising a third injector insert constructed and arranged to couple to the injector assembly, the third injector adapter comprising an inlet and an outlet, in which the inlet of the third injector insert comprises a substantially inert non-glass, non-stainless steel material. 
     
     
         131 . A kit comprising an injector insert constructed and arranged to couple to an injector assembly, the injector insert comprising an inlet and an outlet, in which the inlet comprises a substantially inert metal oxide material. 
     
     
         132 . The kit of  claim 131 , further comprising the injector assembly. 
     
     
         133 . The kit of  claim 131 , further comprising an additional injector insert constructed and arranged to couple to the injector assembly, the additional injector insert comprising an inlet and an outlet, in which the inlet of the additional injector insert comprises a substantially inert metal oxide material. 
     
     
         134 . The kit of  claim 133 , in which the substantially inert metal oxide material of the inlet of the additional injector insert is different than the substantially inert metal oxide material of the inlet of the injector insert. 
     
     
         135 . The kit of  claim 133 , further comprising a third injector insert constructed and arranged to couple to the injector assembly, the third injector insert comprising an inlet and an outlet, in which the inlet of the third injector insert comprises a substantially inert metal oxide material. 
     
     
         136 . A kit comprising an injector insert constructed and arranged to couple to an injector assembly, the injector insert comprising an inlet and an outlet, in which the inlet comprises a non-catalytic metal oxide material present in an effective amount to deter catalysis by the inlet. 
     
     
         137 . The kit of  claim 136 , further comprising the injector assembly. 
     
     
         138 . The kit of  claim 136 , further comprising an additional injector insert constructed and arranged to couple to the injector assembly, the additional injector insert comprising an inlet and an outlet, in which the inlet of the additional injector insert comprises a non-catalytic metal oxide material present in an effective amount to deter catalysis by the inlet of the additional injector insert. 
     
     
         139 . The kit of  claim 138 , in which the non-catalytic metal oxide material of the inlet of the additional injector insert is different than the non-catalytic metal oxide material of the inlet of the injector insert. 
     
     
         140 . The kit of  claim 138 , further comprising a third injector insert constructed and arranged to couple to the injector assembly, the third injector insert comprising an inlet and an outlet, in which the inlet of the third injector insert comprises a non-catalytic metal oxide material present in an effective amount to deter catalysis by the inlet of the third injector insert. 
     
     
         141 . A method of facilitating chromatographic analysis of a sample, the method comprising providing an injector insert comprising an inlet and an outlet, in which the insert is constructed and arranged to couple to an injector assembly to fluidically couple a fluid flow path of the injector assembly to the inlet, in which the inlet comprises a substantially inert metal material. 
     
     
         142 . A method of facilitating chromatographic analysis of a sample, the method comprising providing an injector insert comprising an inlet and an outlet, in which the insert is constructed and arranged to couple to an injector assembly to fluidically couple a fluid flow path of the injector assembly to the inlet, in which the inlet comprises a non-catalytic metal material present in an effective amount to deter catalysis by the inlet. 
     
     
         143 . A method of facilitating chromatographic analysis of a sample, the method comprising providing a fluid injector comprising an inlet and an outlet, in which the inlet of the fluid injector is fluidically coupled to a fluid flow path, in which the inlet comprises a non-catalytic metal material present in an major amount to deter catalysis. 
     
     
         144 . A method of facilitating chromatographic analysis of a sample, the method comprising providing a fluid injector comprising an inlet and an outlet, in which the inlet of the fluid injector is fluidically coupled to a fluid flow path, in which the inlet comprises a major amount of a substantially inert metal material. 
     
     
         145 . A method of facilitating chromatographic analysis of a sample, the method comprising providing a fluid injector insert comprising an inlet and an outlet, in which the inlet comprises a non-catalytic, non-glass material present in an effective amount to deter catalysis by the inlet. 
     
     
         146 . A method of facilitating chromatographic analysis of a sample, the method comprising providing a fluid injector insert comprising an inlet and an outlet, in which the inlet comprises a substantially inert non-glass, non-stainless steel material. 
     
     
         147 . A method of facilitating chromatographic analysis of a sample, the method comprising providing a fluid injector insert comprising an inlet and an outlet, in which the insert is constructed and arranged to couple to an injector assembly to fluidically couple the inlet to a fluid flow path of the injector assembly, in which the inlet comprises a substantially inert metal oxide material. 
     
     
         148 . A method of facilitating chromatographic analysis of a sample, the method comprising providing a fluid injector insert comprising an inlet and an outlet, in which the insert is constructed and arranged to couple to an injector assembly to fluidically couple the inlet to a fluid flow path of the injector assembly, in which the inlet comprises a non-catalytic metal oxide material present in an effective amount to deter catalysis by the inlet. 
     
     
         149 . A method of facilitating chromatographic analysis of a sample, the method comprising providing a fluid injector comprising an inlet and an outlet, in which the inlet comprises a non-catalytic metal oxide material present in an major amount to deter catalysis. 
     
     
         150 . A method of facilitating chromatographic analysis of a sample, the method comprising providing a fluid injector comprising an inlet and an outlet, in which the inlet comprises a substantially inert metal oxide material. 
     
     
         151 . A method of facilitating chromatographic analysis of a sample, the method comprising providing an injector assembly comprising an injector housing comprising a fluid flow path, and an injector insert coupled to the injector housing, the injector insert comprising an inlet and an outlet, in which the fluid flow path of the injector housing is fluidically coupled to the inlet, in which the inlet comprises a substantially inert metal material. 
     
     
         152 . A method of facilitating chromatographic analysis of a sample, the method comprising providing an injector assembly comprising an injector housing comprising a fluid flow path, and an injector insert coupled to the injector housing, the injector insert comprising an inlet and an outlet, in which the fluid flow path of the injector housing is fluidically coupled to the inlet, in which the inlet comprises a non-catalytic metal material present in an effective amount to deter catalysis by the inlet. 
     
     
         153 . A method of facilitating chromatographic analysis of a sample, the method comprising providing an injector assembly comprising an injector housing comprising a fluid flow path, and an injector insert coupled to the injector housing, the injector insert comprising an inlet and an outlet, in which the fluid flow path of the injector housing is fluidically coupled to the inlet, in which the inlet comprises a substantially inert metal oxide material. 
     
     
         154 . A method of facilitating chromatographic analysis of a sample, the method comprising providing an injector assembly comprising an injector housing comprising a fluid flow path, and an injector insert coupled to the injector housing, the injector insert comprising an inlet and an outlet, in which the fluid flow path of the injector housing is fluidically coupled to the inlet, in which the inlet comprises a non-catalytic metal oxide material present in an major amount to deter catalysis by the inlet. 
     
     
         155 . A method of facilitating chromatographic analysis of a sample, the method comprising providing an injector assembly comprising an injector housing comprising a fluid flow path, and an injector insert coupled to the injector housing, the injector insert comprising an inlet and an outlet, in which the fluid flow path of the injector housing is fluidically coupled to the inlet, in which the insert comprises a non-catalytic, non-glass material present in an effective amount to deter catalysis by the inlet. 
     
     
         156 . A method of facilitating chromatographic analysis of a sample, the method comprising providing an injector assembly comprising an injector housing comprising a fluid flow path, and an injector insert coupled to the injector housing, the injector insert comprising an inlet and an outlet, in which the fluid flow path of the injector housing is fluidically coupled to the inlet, in which the inlet comprises a substantially inert non-glass, non-stainless steel material.