Feedstock Solution Flow Concentration System

Abstract

A feedstock solution flow concentration system, which has a first step for counterflowing or parallel flowing a feedstock solution flow a containing a solute and a solvent b, and a draw solution flow d via a forward osmosis membrane o and transferring the solvent b in the feedstock solution flow a to the draw solution flow d to obtain a concentrated feedstock solution flow c, which is the feedstock solution flow which has been concentrated, and a diluted draw solution flow e, which is the draw solution flow which has been diluted.

1 . A feedstock solution flow concentration system, which has a first step for counterflowing or parallel flowing a feedstock solution flow containing at least a solute and a solvent and a draw solution flow via a forward osmosis membrane and transferring the solvent in the feedstock solution flow to the draw solution flow to obtain a concentrated feedstock solution flow, which is the feedstock solution flow which has been concentrated, and a diluted draw solution flow, which is the draw solution flow which has been diluted, wherein
 the draw solution flow contains a draw substance, a common solute, and a solvent,   the solvents of the feedstock solution flow and the draw solution flow both contain water,   the common solute is a solute which is common between the feedstock solution flow and the draw solution flow and is the same solute as at least one type of solute among the solutes contained in the feedstock solution flow, and   the concentration of the common solute in the draw solution flow is 1% to less than 100% of the concentration of the common solute in the feedstock solution flow.   
     
     
         2 . The system according to  claim 1 , wherein the number average molecular weight of the common solute is 15,000 or less. 
     
     
         3 . The system according to  claim 1 , wherein the common solute is one or more selected from an ester, a terpene, a phenylpropanoid, a nucleic acid, a protein, a protein preparation, a vaccine, a sugar, a peptide, an amino acid, a natural product pharmaceutical, a small molecule pharmaceutical, an antibiotic, an antibiotic, a vitamin, an inorganic salt, a protonic polar organic compound, and an aprotic polar organic compound. 
     
     
         4 . The system according to  claim 3 , wherein the common solute comprises:
 a cation having at least one element selected from the group consisting of sodium, magnesium, phosphorus, potassium, calcium, chromium, manganese, iron, cobalt, copper, zinc, selenium, and molybdenum, and   an anion having at least one element selected from the group consisting of oxygen, sulfur, nitrogen, chlorine, and iodine.   
     
     
         5 . The system according to  claim 1 , wherein the concentration of the common solute in the draw solution flow is 6% to 96% of the concentration of the common solute in the feedstock solution flow. 
     
     
         6 . The system according to  claim 1 , wherein the concentration of the common solute in the draw solution flow is 30% to 96% of the concentration of the common solute in the feedstock solution flow. 
     
     
         7 . The system according to  claim 1 , further comprising a second step in which a solvent is separated from the draw solution flow to obtain a concentrated draw solution flow, which is the draw solution flow which has been concentrated. 
     
     
         8 . The system according to  claim 7 , further comprising means for using, in the first step, a draw solution flow prepared by mixing the diluted draw solution flow obtained in the first step and the concentrated draw solution flow obtained in the second step. 
     
     
         9 . The system according to  claim 7 , wherein the second flow is carried out using a membrane distillation process using a semipermeable membrane. 
     
     
         10 . The system according to  claim 1 , wherein the forward osmosis membrane is used in the form of a forward osmosis membrane module constituted by fiber bundle of a plurality of hollow fibers. 
     
     
         11 . The system according to  claim 10 , wherein the forward osmosis membrane is composite hollow fiber having an active separation layer composed of a thin polymer membrane on an inner surface of a hollow fiber-like porous support membrane. 
     
     
         12 . The system according to  claim 1 , wherein
 the feedstock solution flow is a food, pharmaceutical, pharmaceutical ingredient, pharmaceutical raw material, or pharmaceutical intermediate.   
     
     
         13 . The system according to  claim 11 , wherein
 the porous support membrane consists of polyethersulfone or polysulfone, or both of them, and   the active separation layer is composed of a thin polymer membrane of polyamide.   
     
     
         14 . The system according to  claim 3 , wherein the concentration of the common solute in the draw solution flow is 6% to 96% of the concentration of the common solute in the feedstock solution flow. 
     
     
         15 . The system according to  claim 3 , wherein the concentration of the common solute in the draw solution flow is 30% to 96% of the concentration of the common solute in the feedstock solution flow. 
     
     
         16 . The system according to  claim 3 , wherein the forward osmosis membrane is used in the form of a forward osmosis membrane module constituted by a fiber bundle of a plurality of hollow fibers. 
     
     
         17 . The system according to  claim 16 , wherein the forward osmosis membrane is a composite hollow fiber having an active separation layer composed of a thin polymer membrane on an inner surface of a hollow fiber-like porous support membrane. 
     
     
         18 . The system according to  claim 17 , wherein
 the porous support membrane consists of polyethersulfone or polysulfone, or both of them, and   the active separation layer is composed of a thin polymer membrane of polyamide.   
     
     
         19 . The system according to  claim 3 , wherein
 the concentration of the common solute in the draw solution flow is 6% to 96% of the concentration of the common solute in the feedstock solution flow,   the forward osmosis membrane is used in the form of a forward osmosis membrane module constituted by a fiber bundle of a plurality of hollow fibers,   the forward osmosis membrane is a composite hollow fiber having an active separation layer composed of a thin polymer membrane on an inner surface of a hollow fiber-like porous support membrane,   the porous support membrane consists of polyethersulfone or polysulfone, or both of them, and   the active separation layer is composed of a thin polymer membrane of polyamide.