Multiple Tissue Layer Electroporation Applicator and Device

Abstract

The present invention relates to dual depth electroporation devices capable of electorporating both muscle tissue and skin tissue in a single application in order to generate a broad immune response in a subject, and uses of the same.

What is claimed is: 
     
         1 . An array for dual depth electroporation of both muscle tissue and skin tissue in a single application, the array comprising:
 a first set of electrodes configured for intramuscular delivery of a first electrical pulse, the first set of electrodes having a length of about 10 mm to about 35 mm; and   a second set of electrodes configured for intradermal delivery of a second electrical pulse, the second set of electrodes having a length of about 0.01 mm to about 4 mm,   wherein the array is configured such that the first set of electrodes is positioned for intramuscular delivery at the same time the second set of electrodes is positioned for intradermal delivery.