Integrated, molecular, omics, immunotherapy, metabolic, epigenetic, and clinical database

Abstract

The disclosure describes a patient registry data system that can be used to aggregate clinical, molecular, and immune parameters involved in disease initiation, progression, and response to treatment. The disclosure can allow participants, researchers, and physicians to visualize data based on parameters, such as participant demographics and immune system data.

1 - 15 . (canceled) 
     
     
         16 . A computer program product comprising a non-transitory computer-readable medium having computer-executable code encoded therein, the computer-executable code adapted to be executed to implement a method for providing a healthcare data visualization system, the method comprising:
 a) providing a healthcare data visualization system, wherein the healthcare data visualization system comprises:
 i) a subportal; 
 ii) an eligibility determination module; 
 iii) an online consent module; 
 iv) a parameter selection module; 
 v) a data analysis module; 
 vi) a visualization module; and 
 vii) an output module; 
   b) receiving, from a subject via the subportal, information regarding the subject, wherein the information comprises an indicator of a disease specific to the subject;   c) determining, by the eligibility determination module, eligibility of the subject for inclusion in an integrated clinical database based on the information regarding the subject that was received;   d) triggering, by the online consent module, transmission of an online consent form to the subject when the subject is determined to be eligible for inclusion in the integrated clinical database;   e) in response to receiving a consent in the online consent form, automatically triggering a transmission of medical data related to the subject from an electronic medical record (EMR) database to the subportal;   f) processing, by the subportal, the medical data and data obtained from a biological sample from the subject, thereby generating processed data;   g) selecting, by the parameter selection module, a parameter describing the subject;   h) analyzing, by the data analysis module, the processed data using the parameter describing the subject, thereby generating analyzed data about the disease specific to the subject;   i) generating, by the visualization module, (i) a first visual representation of the analyzed data about the disease specific to the subject, wherein the first visual representation is configured to engage the subject in a course of treatment personalized for the subject and includes information about the subject relative to a group of subjects, wherein the group of subjects are associated a disease same to the disease specific to the subject, and (ii) a second visual representation of the analyzed data of the disease associated with the group of subjects, wherein the second visual representation is displayed in a format different from a visualization format of the first visual representation; and   j) outputting, by the output module, the first visual representation of the analyzed data specific to the subject to a first portal and the second visual representation of the analyzed data to a second portal.   
     
     
         17 . The computer program product of  claim 16 , wherein the visualization format of the first visual representation is a personal visualization format that is customized to the subject. 
     
     
         18 . The computer program product of  claim 16 , wherein the first portal is configured to permit the subject to visualize the first visual representation based on the parameter describing the subject. 
     
     
         19 . The computer program product of  claim 18 , wherein the parameter is related to demographic information of the subject. 
     
     
         20 . The computer program product of  claim 18 , wherein the parameter is related to a disease status of the subject. 
     
     
         21 . The computer program product of  claim 16 , wherein the first portal is further configured to receive an input from the subject indicating a change of the parameter. 
     
     
         22 . The computer program product of  claim 16 , wherein the second portal is configured to allow a physician to modify the course of treatment personalized for the subject. 
     
     
         23 . The computer program product of  claim 22 , wherein the second portal is further configured to allow the physician to visualize a time progression of the disease specific to the subject or the disease associated with the group of subjects. 
     
     
         24 . The computer program product of  claim 22 , wherein the second portal is further configured to allow the physician to visualize a time progression of the disease associated with the group of subjects. 
     
     
         25 . The computer program product of  claim 16 , wherein the analyzed data specific to the subject comprises an immune phenotype of the subject. 
     
     
         26 . The computer program product of  claim 16 , wherein the analyzed data specific to the subject comprises proteomics data of the subject. 
     
     
         27 . The computer program product of  claim 16 , wherein the analyzed data specific to the subject comprises genomics data of the subject. 
     
     
         28 . The computer program product of  claim 16 , wherein the first visual representation displays demographic data of the subject. 
     
     
         29 . The computer program product of  claim 16 , wherein the first portal and the second portal are configured for allowing a communication among the subject, a physician, and a researcher. 
     
     
         30 . The computer program product of  claim 16 , wherein the method further comprises:
 a) identifying, by the data analysis module, a plan of care that is needed by the subject based on the analyzed data specific to the subject, and   b) communicating, by the output module, the plan of care to the subject based on the analyzed data specific to the subject.   
     
     
         31 . The computer program product of  claim 16 , wherein the method further comprises enrolling the subject in a study of the disease specific to the subject through the online consent module when the subject is determined to be eligible for inclusion in the integrated clinical database. 
     
     
         32 . The computer program product of  claim 16 , wherein the healthcare data visualization system further comprises a sample collection module, and the method further comprises instructing, by the sample collection module, shipment of a sample collection kit to the subject in response to receiving the consent in the online consent form. 
     
     
         33 . The computer program product of  claim 32 , wherein the method further comprises transmitting, by the sample collection module, a blood sample request and label printing to the subject in response to receiving the consent in the online consent form. 
     
     
         34 . The computer program product of  claim 16 , wherein the healthcare data visualization system further comprises a participant survey module, and the method further comprises automatically triggering a transmission, by the participant survey module, a survey to the subject in response to receiving the consent in the online consent form.