Trans-resveratrol topical medication for the treatment of pain and method of manufacture thereof

Abstract

The invention provides a topical pain medication and a method of manufacturing and suing the same. In one embodiment, the medication includes: ( 1 ) enriched resveratrol having a concentration of trans-resveratrol therein that substantially exceeds the natural concentrations of trans-resveratrol in naturally occurring resveratrol, and ( 2 ) at least one inactive ingredient configured to mix with the resveratrol to form the topical medication. In one embodiment, the method includes: ( 1 ) processing resveratrol to increase the concentration of trans-resveratrol therein and ( 2 ) mixing at least one inactive ingredient with the resveratrol to form the topical medication.

1 - 16 . (canceled) 
     
     
         17 . A topical pharmaceutical composition consisting of:
 inactive ingredients glycerin, phenoxyethanol, and water;   at least one other inactive ingredient that affects the ease of topical application of the pharmaceutical composition or affects the aesthetic properties of the pharmaceutical composition,   resveratrol comprising at least 90% trans-resveratrol, and   an additional agent selected from the group consisting of methyl salicylate, trolamine salicylate, menthol, camphor, lidocaine, benzocaine, dibucaine, prilocaine, capsaicin, diclofenac sodium gel, hydrocortisone, clobetasol, diphenhydramine, ibuprofen, and ketoprofen.   
     
     
         18 . The composition of  claim 17 , wherein the resveratrol concentration is at least 0.8% mass by volume of the composition. 
     
     
         19 . The composition of  claim 18 , wherein the resveratrol concentration is about 1% mass by volume of the composition. 
     
     
         20 . The composition of  claim 18 , wherein the resveratrol concentration is about 2% mass by volume of the composition. 
     
     
         21 . The composition of  claim 17 , wherein the resveratrol comprises about 1% to 10% cis-resveratrol. 
     
     
         22 . The composition of  claim 17 , wherein the additional agent is methyl salicylate. 
     
     
         23 . The composition of  claim 17 , wherein the additional agent is lidocaine. 
     
     
         24 . A topical pharmaceutical composition consisting of:
 inactive ingredients glycerin, phenoxyethanol, and water;   at least one other inactive ingredient that affects the ease of topical application of the pharmaceutical composition or affects the aesthetic properties of the pharmaceutical composition;   resveratrol comprising at least 90% trans-resveratrol;   an antimicrobial agent; and   an additional agent selected from the group consisting of methyl salicylate, trolamine salicylate, menthol, camphor, lidocaine, benzocaine, dibucaine, prilocaine, capsaicin, diclofenac sodium gel, hydrocortisone, clobetasol, diphenhydramine, ibuprofen, and ketoprofen.   
     
     
         25 . The composition of  claim 24 , wherein the antimicrobial agent is selected from the group consisting of silver, gentamicin, and mafenide acetate. 
     
     
         26 . The composition of  claim 25 , wherein the antimicrobial agent is silver. 
     
     
         27 . The composition of  claim 24 , wherein the additional agent is methyl salicylate. 
     
     
         28 . The composition of  claim 24 , wherein the additional agent is lidocaine. 
     
     
         29 . The composition of  claim 24 , wherein the resveratrol concentration is at least 0.8% mass by volume of the composition. 
     
     
         30 . The composition of  claim 29 , wherein the resveratrol concentration is about 1% mass by volume of the composition. 
     
     
         31 . The composition of  claim 29 , wherein the resveratrol concentration is about 2% mass by volume of the composition.