Methods and apparatus for treating a wound

Abstract

Methods for treating a wound or promote wound healing are provided, comprising the step of administering a composition including an effective amount of β-1 adrenergic receptor antagonist to a subject in need thereof. Also provided is apparatus for wound healing, comprising a dressing and a composition including an effective amount of β-1 adrenergic receptor antagonist.

What is claimed is: 
     
         1 . A method for treating a deep fissure in a patient comprising the step of administering a composition comprising an effective amount of a β-1 adrenergic receptor antagonist to the patient in need thereof. 
     
     
         2 . The method of  claim 1 , wherein said deep fissure is induced by targeted therapy. 
     
     
         3 . The method of  claim 2 , wherein the β-1 adrenergic receptor antagonist is atenolol, betaxolol, bisoprolol, esmolol, acebutolol, metoprolol, nebivolol or any combination thereof. 
     
     
         4 . The method of  claim 1 , wherein the β-1 adrenergic receptor antagonist is atenolol, betaxolol, bisoprolol, esmolol, acebutolol, metoprolol, nebivolol or any combination thereof. 
     
     
         5 . The method of  claim 1 , further comprising administering an additional therapeutic agent for wound healing. 
     
     
         6 . The method of  claim 5 , wherein the additional therapeutic agent for wound healing is growth factors, cytokines, chemokines, antibodies, antibiotics, immunosuppressive agents, steroids, zinc, hyperbaric oxygen, anti-fungal agents, anti-viral agents, stem cells, bioengineered skin, debriding agents or any combination thereof.