Managing Patient Body Temperature Using Endovascular Heat Exchange in Combination With Body Surface Heat Exchange

Abstract

The present disclosure includes devices, systems and related methods useable for controlling a patient's body temperature by endovascular heat exchange as well as body surface heat exchange.

1 .- 55 . (canceled) 
     
     
         56 . A system for controlling a body temperature of a subject, the system comprising:
 a first source of a heat exchange fluid;   a first heat exchange device configured to heat or cool the body temperature of the subject by transferring heat between the heat exchange fluid and the subject;   a first pump configured to circulate the heat exchange fluid through the first heat exchange device from the first source of the heat exchange fluid;   a controller configured to control the first pump to circulate the heat exchange fluid; and   a removable secondary heat exchange system that is configured to interface with the controller, the removable secondary heat exchange system comprising:
 a second source of a heat exchange fluid; 
 a second pump; 
 a second heat exchange device through which the second pump is configured to circulate heat exchange fluid from the second source; and 
 an electronic storage medium storing instructions configured to cause the controller to control the second pump to control the body temperature of the subject. 
   
     
     
         57 . The system of  claim 56 , wherein the second heat exchange device comprises a body surface heat exchange device, and wherein the first heat exchange device comprises an endovascular heat exchange device. 
     
     
         58 . The system of  claim 56 , further comprising:
 an air trap configured to remove air from a first fluid loop in communication with the first pump or a second fluid loop in communication with the second pump.   
     
     
         59 . The system of  claim 56 , wherein the controller is configured to detect that the second pump, the second source, or the second heat exchange device is connected for heating or cooling the body of the subject, wherein the controller automatically controls the second pump to circulate the heat exchange fluid from the second source in response to the detecting. 
     
     
         60 . The system of  claim 56 , wherein the controller is configured to perform operations comprising:
 receiving, through a user interface, a selection of a mode of operation, the mode of operation comprising one of:
 a first mode wherein heated or cooled heat exchange fluid is circulated through the first heat exchange device comprising an endovascular heat exchange device; 
 a second mode wherein heated or cooled heat exchange fluid is circulated through the second heat exchange device comprising a body surface heat exchange device; and 
 a third mode wherein heated or cooled heat exchange fluid is circulated through both the endovascular heat exchange device and the body surface heat exchange device; and 
   in response to receiving the selection of the mode of operation, controlling the body temperature of the subject in accordance with the selected mode of operation.   
     
     
         61 . The system of  claim 60 , wherein the third mode comprises at least two sub-modes selected from:
 a first sub-mode wherein the endovascular heat exchange device and the body surface heat exchange device simultaneously cool or warm;   a second sub-mode wherein one of the endovascular heat exchange device and the body surface heat exchange device cools while the other of the endovascular heat exchange device and the body surface heat exchange device warms; and   a third sub-mode wherein, for an initial period, the endovascular heat exchange device and the body surface heat exchange device simultaneously cool or warm and, for a subsequent period, one of the endovascular heat exchange device and the body surface heat exchange device cools while the other of the endovascular heat exchange device and the body surface heat exchange device warms.   
     
     
         62 . The system of  claim 56 , further comprising a heater or cooler configured for heating or cooling one or both of the first source of the heat exchange fluid and the second source of the heat exchange fluid. 
     
     
         63 . The system of  claim 62 , wherein the heater or cooler comprises a coldwell, and wherein the second heat exchange device comprises a circulation coil through which the heat exchange fluid from the second source flows, the circulation coil configured to be disposed within the coldwell. 
     
     
         64 . The system of  claim 62 , wherein the heater or cooler comprises heat exchange plates, and wherein second heat exchange device comprises a cassette through which the heat exchange fluid from the second source flows, the cassette configured to be disposed between the heat exchange plates. 
     
     
         65 . The system of  claim 56 , wherein the removable secondary heat exchange system comprises an air separator that prevents air from entering the second pump. 
     
     
         66 . The system of  claim 56 , wherein the removable secondary heat exchange system comprises a dual lumen spike that for connecting tubing to the second source of the heat exchange fluid, the dual lumen spike configured to cause air to collect at a top of a reservoir of the second source of the heat exchange fluid as a liquid level lowers in the reservoir. 
     
     
         67 . The system of  claim 56 , wherein the removable secondary heat exchange system comprises a capture device that captures warm air that exhausts from a heater that warms the a heat exchange fluid from the first source; and
 a conduit for channeling warm air from the capture device to the second heat exchange device that comprises a body surface warming device.   
     
     
         68 . A removable secondary heat exchange system that is configured to interface with a controller of a primary heat exchange system that controls a body temperature of a subject, the removable secondary heat exchange system comprising:
 a source of a heat exchange fluid;   a pump;   a heat exchange device through which the pump is configured to circulate heat exchange fluid from the source of the heat exchange fluid; and   an electronic storage medium storing instructions configured to cause the controller to control the pump to control the body temperature of the subject.   
     
     
         69 . The system of  claim 68 , wherein the heat exchange device comprises a body surface heat exchange device. 
     
     
         70 . The system of  claim 68 , further comprising:
 an air trap configured to remove air from a fluid loop in communication with the pump.   
     
     
         71 . The system of  claim 68 , wherein the controller is configured to detect that the pump, the source, or the heat exchange device is connected for heating or cooling the body of the subject, wherein the controller automatically controls the pump to circulate the heat exchange fluid in response to the detecting. 
     
     
         72 . The system of  claim 71 , wherein the controller is configured to perform operations comprising, in response to the detecting:
 receiving, through a user interface, a selection of a mode of operation, the mode of operation comprising one of:
 a first mode wherein heated or cooled heat exchange fluid is circulated through a second heat exchange device comprising an endovascular heat exchange device; 
 a second mode wherein heated or cooled heat exchange fluid is circulated through the heat exchange device comprising a body surface heat exchange device; and 
 a third mode wherein heated or cooled heat exchange fluid is circulated through both the endovascular heat exchange device and the body surface heat exchange device; and 
   in response to receiving the selection of the mode of operation, controlling the body temperature of the subject in accordance with the selected mode of operation.   
     
     
         73 . The system of  claim 72 , wherein the third mode comprises at least two sub-modes selected from:
 a first sub-mode wherein the endovascular heat exchange device and the body surface heat exchange device simultaneously cool or warm;   a second sub-mode wherein one of the endovascular heat exchange device and the body surface heat exchange device cools while the other of the endovascular heat exchange device and the body surface heat exchange device warms; and   a third sub-mode wherein, for an initial period, the endovascular heat exchange device and the body surface heat exchange device simultaneously cool or warm and, for a subsequent period, one of the endovascular heat exchange device and the body surface heat exchange device cools while the other of the endovascular heat exchange device and the body surface heat exchange device warms.   
     
     
         74 . The system of  claim 68 , wherein the heat exchange device comprises a circulation coil through which the heat exchange fluid flows, the circulation coil configured to be disposed within a coldwell having a temperature that is controlled by the controller. 
     
     
         75 . The system of  claim 68 , wherein the heat exchange device a cassette through which the heat exchange fluid flows, the cassette configured to be disposed between heat exchange plates having a temperature that is controlled by the controller.