US2022047583A1PendingUtilityA1
Product and method for treating diarrhea
Est. expiryMar 14, 2033(~6.7 yrs left)· nominal 20-yr term from priority
Inventors:Reed B. Hogan, Ii
A61K 31/495A61K 31/426A61K 45/06A61P 1/12A61K 9/0053A61K 31/341A61K 9/20A61K 9/48A61K 2300/00A61K 31/4164Y02A50/30
66
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Claims
Abstract
A method of treating diarrhea in a patient includes administering an H1 receptor antagonist and an H2 receptor antagonist to the patient.
Claims
exact text as granted — not AI-modified1 . A method of treating diarrhea in a patient, comprising administering an H1 receptor antagonist and an H2 receptor antagonist to the patient, wherein the patient does not have mastocytic enterocolitis.
2 . (canceled)
3 . The method of claim 1 , wherein the H1 receptor antagonist comprises cetirizine, levocetirizine, or mixtures thereof.
4 . The method of claim 1 , wherein the H2 receptor antagonist comprises famotidine, ranitidine, or mixtures thereof.
5 . The method of claim 1 , wherein the H1 receptor antagonist and the H2 receptor antagonist are administered simultaneously.
6 . The method of claim 1 , wherein the H1 receptor antagonist and the H2 receptor antagonist are administered once per day for at least 2 days.
7 . The method of claim 1 , wherein the H1 receptor antagonist and the H2 receptor antagonist are administered once per day for at least 7 days.
8 - 17 . (canceled)
18 . The method of claim 1 , wherein the H1 receptor antagonist comprises cetirizine and the cetirizine is administered in an amount of 5 to 20 mg.
19 . The method of claim 1 , wherein the H2 receptor antagonist comprises famotidine and the famotidine is administered in an amount of 10 to 40 mg.
20 . The method of claim 1 , wherein the H1 receptor antagonist comprises cetirizine,
the H2 receptor antagonist comprises famotidine, and the famotidine and the cetirizine are administered together as a unit dosage form.
21 - 40 . (canceled)
41 . A pharmaceutical composition for treating diarrhea, comprising:
an H1 receptor antagonist, and an H2 receptor antagonist, wherein the H2 receptor antagonist is not ranitidine, and the pharmaceutical composition is an oral dosage form.
42 . (canceled)
43 . The pharmaceutical composition of claim 41 , wherein the H1 receptor antagonist comprises cetirizine, levocetirizine, or mixtures thereof.
44 . The pharmaceutical composition of claim 41 , wherein the H2 receptor antagonist comprises famotidine.
45 . The pharmaceutical composition of claim 41 , wherein the H1 receptor antagonist comprises cetirizine, and the H2 receptor antagonist comprises famotidine.
46 . The pharmaceutical composition of claim 41 , wherein the oral dosage form comprises a unit dosage form.
47 . The pharmaceutical composition of claim 41 , wherein the oral dosage form comprises at least one tablet or capsule.
48 . The pharmaceutical composition of claim 41 , wherein the oral dosage form further comprises sodium, and glucose or a glucose-containing saccharide.
49 . The pharmaceutical composition of claim 41 , wherein the oral dosage form further comprises an oral rehydration solution.
50 . The pharmaceutical composition of claim 41 , wherein the oral dosage form comprises a plurality of unit dosage forms.
51 - 80 . (canceled)
81 . The method of claim 45 , wherein the cetirizine is present in an amount of 5 to 20 mg.
82 . The method of claim 45 , wherein the famotidine is present in an amount of 10 to 40 mg.Cited by (0)
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