Multi-chambered balloon catheter devices and methods

Abstract

Catheter devices/systems and methods therefrom are described herein for treating acute kidney injury, especially the contrast-induced acute kidney injury wherein the devices may prevent the contrast dyes from entering into kidney and/or facilitate blood flow of kidney by said catheter system.

What is claimed is: 
     
         1 . A device for occluding vasculature of a subject, the device comprising:
 a catheter shaft comprising a proximal portion and a distal portion; and   an inflatable balloon disposed on the proximal portion of the catheter shaft,   wherein the inflatable balloon comprises a first balloon chamber and a second balloon chamber, the first and second balloon chambers being formed by one or more of (i) fixedly attaching a first length of the inflatable balloon to the catheter shaft along a longitudinal axis of the catheter to form a first longitudinal bond extending thereon or (ii) fixedly attaching a second length of the inflatable balloon to the catheter shaft along the longitudinal axis of the catheter to form a second longitudinal bond extending thereon,   wherein the inflatable balloon has an expanded configuration which, when advanced into a blood vessel and positioned adjacent blood vessel ostia of the subject, is sized to occlude the blood vessel ostia while allowing blood flow over the catheter shaft, and   wherein the distal portion is configured to remain outside a body of the subject when the proximal portion is positioned adjacent blood vessel ostia of the subject.   
     
     
         2 . The device of  claim 1 , wherein the first balloon chamber is disposed on a first lateral side of the proximal portion and the second balloon chamber is disposed on a second lateral side of the proximal portion. 
     
     
         3 . The device of  claim 1 , wherein the first balloon chamber and second balloon chamber are each longitudinal cylindrical balloon chambers. 
     
     
         4 . The device of  claim 1 , wherein the first balloon chamber and the second balloon chamber are in fluid communication with one another. 
     
     
         5 . The device of  claim 1 , wherein the first balloon chamber and the second balloon chamber are configured to inflate simultaneously. 
     
     
         6 . The device of  claim 1 , wherein the first longitudinal bond extends 80% of the length of the inflatable balloon. 
     
     
         7 . The device of  claim 1 , wherein the second longitudinal bond extends 90% of the length of the inflatable balloon. 
     
     
         8 . The device of  claim 1 , wherein the inflatable balloon comprises a figure-eight, dumbbell, or butterfly-like cross section about the catheter shaft disposed therein. 
     
     
         9 . The device of  claim 1 , further comprising one or more position indication features disposed on the expandable balloon. 
     
     
         10 . The device of  claim 9 , wherein the one or more position indication feature comprises one or more radio-opaque markers. 
     
     
         11 . The device of  claim 9 , wherein the one or more radio-opaque marker comprises one or more radio-opaque longitudinal markers. 
     
     
         12 . The device of  claim 11 , wherein the one or more radio-opaque longitudinal markers comprises a plurality of radio-opaque longitudinal markers disposed on the expandable balloon along a longitudinal axis of the expandable balloon. 
     
     
         13 . The device of  claim 11 , wherein the one or more radio-opaque longitudinal markers are configured to indicate the orientation of the expandable balloon when positioned adjacent renal artery ostia of the subject. 
     
     
         14 . The device of  claim 11 , wherein the one or more radio-opaque longitudinal markers are configured to change from a straight configuration to a bowed configuration when expanded adjacent blood vessel ostia of the subject. 
     
     
         15 . The device of  claim 1 , wherein fixedly attaching comprises adhering.