Soft embolic implant

Abstract

Soft embolic implants exhibiting secondary shapes are disclosed. Some of the embolic implants exhibit progressively increasing softness from the distal end to the proximal end of the coil. The embolic implants have a primary coil, an optional second coil, a shape wire, and a stretch resistant fiber disposed in the lumen of the primary coil. An optional distal support wire is also disclosed. The embolic implants include a proximal constraint assembly configured to be releaseably retained by a delivery device. Disposed near each end of some of the implants are elliptical hole washers through which the shape wire and the stretch resistant fiber are threaded. The embolic implants have a primary, linear configuration for delivery through an implant tool, and a secondary configuration after deployment from the implant tool. The secondary shape can be J-shaped, helical, spherical, complex, or a combination of shapes.

1 - 39 . (canceled) 
     
     
         40 . An embolic implant comprising:
 a proximal end and a distal end;   a primary coil configured to occlude blood flow in an implanted state, the primary coil comprising a lumen extending through said primary coil;   a proximal constraint assembly disposed at said proximal end; and   a distal assembly disposed at said distal end;   a stretch resistant fiber disposed in said lumen and coupled to the proximal constraint assembly and the distal assembly to prevent elongation of the primary coil; and   a shape memory filament extending through the lumen, wherein said shape memory filament comprises a first, constrained linear configuration and a second configuration that imparts a complex shape on the embolic implant.   
     
     
         41 . The embolic implant according to  claim 40 , wherein said implant further comprises a jacket over the primary coil. 
     
     
         42 . The embolic implant according to  claim 41 , wherein the jacket wraps or encases over the primary coil. 
     
     
         43 . The embolic implant according to  claim 42 , wherein the jacket is constructed from a thrombogenic material. 
     
     
         44 . The embolic implant according to  claim 43 , wherein the thrombogenic material comprises of polyester, polypropylene, or silk. 
     
     
         45 . The embolic implant according to  claim 43 , wherein the thrombogenic material comprises of a monofilament fiber or multi-filament fibers. 
     
     
         46 . The embolic implant according to  claim 45 , wherein the jacket is constructed by wrapping, winding, braiding, threading, or arranging the monofilament fiber or multi-filament fibers in engagement with the primary coil. 
     
     
         47 . The embolic implant according to  claim 41 , wherein the jacket is a sleeve-like structure that is placed or applied directly over the primary coil. 
     
     
         48 . The embolic implant according  claim 40 , wherein said implant further comprises a second coil disposed in said lumen. 
     
     
         49 . The embolic implant according to  claim 48 , wherein said second coil comprises shape memory material, and said second coil comprises a first, constrained linear configuration and a second configuration that is helical, J-shaped, spherical, complex, or a segmented combination of shapes. 
     
     
         50 . The embolic implant according to  claim 40 , said implant further comprising a proximal bond disposed at the proximal end, wherein said proximal bond is affixed to said primary coil, said shape memory filament, or both. 
     
     
         51 . The embolic implant according to  claim 40 , wherein said implant further comprises an annular distal bond affixed to the distal end of said primary coil. 
     
     
         52 . The embolic implant according to  claim 40 , wherein said stretch resistant fiber comprises a first proximal knot, said proximal constraint assembly includes a proximal constraint element configured to be releaseably retained by a delivery device, wherein said proximal constraint element comprises a through hole and said stretch resistant fiber is disposed through said through hole. 
     
     
         53 . The embolic implant according to  claim 40 , the implant further comprising a distal tip disposed at the distal end of the primary coil. 
     
     
         54 . The embolic implant according to  claim 53 , wherein said distal tip comprises a polymer, or an adhesive, or both, said stretch resistant fiber is knotted to form a distal knot, and said distal knot is embedded in said polymer or said adhesive or both. 
     
     
         55 . The embolic implant according to  claim 54 , said implant further comprising a tube segment having a lumen and disposed at said distal end, wherein said stretch resistant fiber is disposed through said lumen, said distal knot is disposed distal to said tube segment, and said tube segment and said distal knot are embedded in said polymer or said adhesive or both. 
     
     
         56 . The embolic implant according to  claim 40 , said implant further comprising a distal tip disposed at the distal end of said primary coil, wherein said distal tip comprises a polymer, or an adhesive or both, said stretch resistant fiber is knotted to form a distal knot, and said distal knot and a distal constraint element are embedded in said polymer or said adhesive or both. 
     
     
         57 . The embolic implant according to  claim 40  wherein said proximal constraint assembly comprises a proximal constraint element having a distal aperture, said stretch resistant fiber engages said distal aperture. 
     
     
         58 . The embolic implant according to  claim 40  wherein said shape memory filament comprises a proximal end, a distal end and a variable diameter, and said variable diameter varies from a lesser diameter near said proximal end to a greater diameter near said distal end.