US2022096586A1PendingUtilityA1

Pharmaceutical composition comprising a fraction of melissa officinalis leaf extract

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Assignee: ANGIOLAB INCPriority: May 22, 2019Filed: May 21, 2020Published: Mar 31, 2022
Est. expiryMay 22, 2039(~12.9 yrs left)· nominal 20-yr term from priority
Inventors:Min Young KimByung-Young ParkHee Suk LeeHyung Soo YuhJeong Eun KimHyun Jeung Kim
A61P 27/16A61K 2236/51A61K 2236/333A61P 29/00A61K 36/53A61K 2236/00A61K 2236/53A61K 2236/39A61P 15/02
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Claims

Abstract

The present invention relates to a pharmaceutical composition for preventing or treating otitis media with effusion comprising a fraction of Melissa officinalis leaf extract as an effective ingredient.

Claims

exact text as granted — not AI-modified
1 . A pharmaceutical composition for preventing or treating otitis media with effusion comprising a fraction of  Melissa officinalis  leaf extract. 
     
     
         2 . The pharmaceutical composition according to  claim 1 , wherein the fraction of the extract is obtained by extracting  Melissa officinalis  leaves with 50 to 100% alcohol, concentrating, fractionating with ethyl acetate, and drying. 
     
     
         3 . The pharmaceutical composition according to  claim 1 , wherein the fraction of  Melissa officinalis  leaf extract is an ethyl acetate fraction of ethanol extract of  Melissa officinalis  leaves. 
     
     
         4 . A method for preventing or treating otitis media with effusion, the method comprising:
 administering to a subject in need thereof a therapeutically effective amount of the pharmaceutical composition comprising the fraction of  Melissa officinalis  leaf extract according to  claim 1 .   
     
     
         5 - 6 . (canceled) 
     
     
         7 . The method composition according to  claim 4 , wherein the fraction of the extract is obtained by extracting  Melissa officinalis  leaves with 50 to 100% alcohol, concentrating, fractionating with ethyl acetate, and drying. 
     
     
         8 . The method according to  claim 4 , wherein the fraction of  Melissa officinalis  leaf extract is an ethyl acetate fraction of ethanol extract of  Melissa officinalis  leaves.

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