Kits and methods of using hyaluronidase to modify polysaccharide fillers and delivery systems

Abstract

Embodiments of the present invention are directed to kits, compositions and methods for modifying and altering polysaccharide fillers and drug delivery systems with the application of hyaluronidase

1 - 16 . (canceled) 
     
     
         17 . A drug delivery system comprising a polysaccharide and hyaluronidase held in a vessel for reconstitution. 
     
     
         18 . The drug delivery system of  claim 17 , wherein said polysaccharide has one or more sugars selected from the group consisting of D-galactose and 3, 6-anhydro-L-galactopyranose. 
     
     
         19 . The drug delivery system of  claim 18 , wherein said polysaccharide is an agarose. 
     
     
         20 . The drug delivery system of  claim 17 , further comprising one or more drugs. 
     
     
         21 . The drug delivery system of  claim 20 , wherein one or more drugs are selected from anesthetic agents, aesthetic agents, or combination thereof. 
     
     
         22 . The drug delivery system of  claim 17 , wherein the hyaluronidase render the polysaccharide in a more fluid state upon reconstitution. 
     
     
         23 . The drug delivery system of  claim 17 , wherein the polysaccharide comprises agarose and neoagarosehexaose. 
     
     
         24 . A kit for performing dermal filling procedures comprising:
 a. a polysaccharide for forming a mass in the body of an animal, wherein said polysaccharide has one or more sugars selected from the group consisting of D-galactose and 3, 6-anhydro-L-galactopyranose; and   b. an hyaluronidase for altering said polysaccharide, for administration with said polysaccharide or to said mass held in the body to effect a modification of said mass.   
     
     
         25 . The kit of  claim 24 , wherein said hyaluronidase is recombinant. 
     
     
         26 . The kit of  claim 24 , wherein said polysaccharide is an agarose. 
     
     
         27 . The kit of  claim 26 , wherein the agarose further comprises neoagarosehexaose.