Microneedle arrays and methods for making and using

Abstract

An array of differing microneedles can be accurately achieved including a film having first and second, outwardly facing major surfaces. The first, outwardly facing major surface has a plurality of stratum corneum piercing microneedles extending therefrom, and the plurality of microneedles includes a plurality of first microneedles having a first benefit agent and a plurality of second microneedles having a second benefit agent.

1 .- 8 . (canceled) 
     
     
         9 . A microneedle array comprising a film having first and second, outwardly facing major surfaces, wherein the first, outwardly facing major surface has a plurality of stratum corneum piercing microneedles extending therefrom, and wherein the plurality of microneedles includes a plurality of first microneedles having a first benefit agent and a plurality of second microneedles having a second benefit agent, wherein individual microneedles comprise at least two distinct benefit agents and at least one individual microneedle comprises a core section and a sheath section. 
     
     
         10 . The microneedle array of  claim 9  wherein the core section of the at least one individual microneedle comprises a rigid composition. 
     
     
         11 . A microneedle array comprising a film having first and second, outwardly facing major surfaces, wherein the first, outwardly facing major surface has a plurality of stratum corneum piercing microneedles extending therefrom, and wherein the plurality of microneedles includes a plurality of first microneedles having a first benefit agent and a plurality of second microneedles having a second benefit agent wherein at least one microneedle has an initial, substantially linear form, extending substantially normal to the first, outwardly facing major surface, and a second, deployed form in which a distal end curves to a hook-like form. 
     
     
         12 .- 13 . (canceled)