Left atrial appendage closure implant

Abstract

A left atrial appendage closure implant may include a support frame including a first bend extending from a proximal collar to a second bend, a first segment extending from the second bend to a third bend, a second segment extending from the third bend to a fourth bend, and a third segment extending from the fourth bend to a distal collar, wherein the support frame is actuatable from a first constrained position to a second flowering position to a third mid-deployment position to a fourth unconstrained position. An implant may include a self-expanding support frame having a circumference and a central longitudinal axis, a membrane disposed over at least a portion of the support frame, and a plurality of anchors arranged into a first row and a second row such that the first row and the second row form a staggered pattern about the circumference of the support frame.

What is claimed: 
     
         1 . An occlusion device for an atrial appendage, the device comprising:
 a proximal collar;   a distal collar; and   a support frame including a plurality of struts extending between the proximal collar and the distal collar and defining an interior volume of the occlusion device, the plurality of struts each having a proximal end fixed to the proximal collar and a distal end fixed to the distal collar;   wherein when in an expanded configuration, the distal collar is positioned proximal of a distalmost extent of the support frame;   wherein the support frame has a proximal section defining a first maximum diameter, a distal section defining a second maximum diameter less than the first maximum diameter, and an intermediate section between the proximal section and the distal section, the intermediate section tapering from the first maximum diameter to the second maximum diameter.   
     
     
         2 . The occlusion device of  claim 1 , wherein the support frame is a monolithic structure cut from a single tubular member. 
     
     
         3 . The occlusion device of  claim 2 , further comprising a plurality of anchors formed integrally with the support frame. 
     
     
         4 . The occlusion device of  claim 3 , wherein the plurality of anchors each extends radially outward from a junction of at least two struts. 
     
     
         5 . The occlusion device of  claim 1 , wherein the support frame is self-expanding. 
     
     
         6 . The occlusion device of  claim 1 , wherein the distal end of each of the plurality of struts extends proximally to the distal collar. 
     
     
         7 . The occlusion device of  claim 1 , wherein the proximal end of each of the plurality of struts extends proximally to the proximal collar. 
     
     
         8 . The occlusion device of  claim 1 , further comprising a filter membrane affixed to at least the proximal section of the support frame. 
     
     
         9 . The occlusion device of  claim 1 , wherein when in the expanded configuration, the proximal collar is positioned at or distal of a proximalmost extent of the support frame. 
     
     
         10 . The occlusion device of  claim 1 , wherein in the expanded configuration, each strut extends radially outward from the proximal collar in a complex curve including a first bend and a second bend, wherein at the second bend, each strut turns distally and radially inward. 
     
     
         11 . The occlusion device of  claim 10 , wherein at the second bend as each strut turns distally and radially inward, a cross-sectional profile of a first segment of the strut extends distally at a first angle of between 5 degrees to 25 degrees relative to a line parallel to a central longitudinal axis of the support frame. 
     
     
         12 . The occlusion device of  claim 11 , wherein the first segment of the strut extends distally and radially inward from the second bend to a third bend where the cross-sectional profile turns radially inward at a sharper angle while still extending distally. 
     
     
         13 . The occlusion device of  claim 12 , wherein a second segment of the strut extends distally from the third bend forms a second angle with the first segment of between 20 degrees to 65 degrees. 
     
     
         14 . The occlusion device of  claim 13 , wherein the second segment extends distally and radially inward from the third bend to a fourth bend, and at the fourth bend, the cross-sectional profile turns proximally and a third segment of the strut extends proximally from the fourth bend to the distal collar. 
     
     
         15 . An occlusion device for an atrial appendage, the device comprising:
 a proximal collar;   a distal collar;   a self-expanding support frame including a plurality of struts extending between the proximal collar and the distal collar and defining an interior volume of the occlusion device, the plurality of struts each having a proximal strut end fixed to the proximal collar and a distal strut end fixed to the distal collar; and   a plurality of anchors disposed on the support frame, the plurality of anchors including hook portions extending radially outward from the support frame;   wherein when in an expanded configuration, the distal collar is positioned within the interior volume of the occlusion device and the proximal collar is positioned at or distal of a proximalmost extent of the support frame;   wherein when in the expanded configuration, each strut extends radially outward from the proximal collar in a complex curve including a first bend and a second bend, wherein at the second bend, each strut turns distally and radially inward forming a tapered surface extending from a first outer diameter at a proximal section of the support frame to a second outer diameter at a distal section of the support frame, where the first outer diameter is larger than the second outer diameter.   
     
     
         16 . The occlusion device of  claim 15 , wherein the plurality of anchors is arranged in a first row of anchors and a second row of anchors such that the plurality of anchors forms a staggered pattern about a circumference of the occlusion device. 
     
     
         17 . The occlusion device of  claim 16 , wherein each of the plurality of anchors extends radially outward from a junction of at least two struts. 
     
     
         18 . The occlusion device of  claim 15 , further comprising a filter membrane affixed to at least the proximal section of the support frame. 
     
     
         19 . The occlusion device of  claim 15 , wherein when in the expanded configuration, the proximal collar is positioned at or distal of the proximalmost extent of the support frame. 
     
     
         20 . An occlusion device for an atrial appendage, the device comprising:
 a proximal collar;   a distal collar; and   a support frame including a plurality of struts extending between the proximal collar and the distal collar, the plurality of struts each having a proximal end fixed to the proximal collar and a distal end fixed to the distal collar;   wherein when in an expanded configuration, the distal collar is positioned proximal of a distalmost extent of the support frame;   wherein the distal end of each of the plurality of struts extends proximally to the distal collar, and the proximal end of each of the plurality of struts extends proximally to the proximal collar;   wherein when in the expanded configuration, each strut extends radially outward from the proximal collar to a bend, wherein at the bend, each strut turns and forms a first tapered surface extending distally and radially inward, each strut forming additional bends extending further radially inward to the distal collar.