US2022133919A1PendingUtilityA1

ONE STEP 64Cu-BaBaSar-RGD2 PRODUCTION METHOD

Assignee: UNIV SOUTHERN CALIFORNIAPriority: Dec 1, 2017Filed: Jan 13, 2022Published: May 5, 2022
Est. expiryDec 1, 2037(~11.3 yrs left)· nominal 20-yr term from priority
A61K 51/0446A61K 51/1241A61K 51/082A61K 2123/00A61K 51/088A61K 51/121A61K 51/0482A61K 51/0497
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Claims

Abstract

A method of preparing a 64Cu-BaBaSar-RGD2 solution is provided. The method includes lyophilizing a solution of BaBaSar-RGD2 and adding a 64Cu solution to the lyophilized BaBaSar-RGD2.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A kit for comprising:
 a lyophilized powder of BaBaSar-RGD 2 , a buffer salt and   instructions for reconstituting the lyophilized powder with a  64 Cu solution comprising  64 CuCl 2 .   
     
     
         2 . The kit according to  claim 1 , wherein the buffer salt is sodium acetate buffer. 
     
     
         3 . The kit according to  claim 1 , wherein the instructions comprise adding the  64 Cu solution to the lyophilized powder. 
     
     
         4 . The kit according to  claim 1 , comprising about 50 μg BaBaSar-RGD 2 . 
     
     
         5 . The kit according to  claim 1 , wherein the kit has a shelf life of over three months at room temperature. 
     
     
         6 . The kit according to  claim 1 , wherein the kit has a shelf life of over a year when stored at a temperature of 2-8° C.

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