Fluid therapy method

Abstract

A fluid therapy method for an ADHF patient includes setting a urine output rate desired threshold, setting one or more desired negative net gain rates, and optionally setting a total fluid loss goal. The urine output of the patient is monitored and fluid is automatically administered to the patient at increasing rates to equal to or approximately match the patient's increasing urine output rates until the patient's urine output rate reaches the set urine output rate desired threshold. Thereafter, fluid is administered to the patient at rates to achieve the set desired negative net gain rate until the fluid loss goal is reached. Thereafter, until the end of therapy, fluid is administered to the patient at rates equal to or approximately equal to the monitored urine output rates.

1 - 23 . (canceled) 
     
     
         24 . A fluid therapy system, comprising:
 a urine measurement device configured to measure urine output from a patient;   a pump fluidly coupled to a hydration fluid source and configured to provide hydration fluid to the patient; and   a controller operably coupled to the urine measurement device and the pump, the controller being configured to—
 obtain a urine output rate of the patient based at least partially on the measured urine output from the urine measurement device, 
 cause the pump to provide the hydration fluid at a first flow rate after obtaining the urine output rate, and 
 after providing the hydration fluid at the first flow rate, cause the pump to provide the hydration fluid at a second flow rate different than the first flow rate, such that a net fluid loss from the patient increases as the urine output rate of the patient increases. 
   
     
     
         25 . The fluid therapy system of  claim 24  wherein the second flow rate is less than the urine output rate. 
     
     
         26 . The fluid therapy system of  claim 24  wherein the second flow rate is greater than the first flow rate. 
     
     
         27 . The fluid therapy system of  claim 24  wherein the controller is further configured to—
 determine the first flow rate based on the urine output rate of the patient at a first time; and 
 determine the second flow rate based on the urine output rate of the patient at a second time different than the first time. 
 
     
     
         28 . The fluid therapy system of  claim 24  wherein the first flow rate of the hydration fluid is equal to or greater than the urine output rate until at least one of (i) a predetermined volumetric amount of urine output is reached or (ii) a predetermined amount of time has elapsed, and wherein the second flow rate of the hydration fluid is less than at least one of the urine output rate or the first flow rate. 
     
     
         29 . The fluid therapy system of  claim 24  wherein the controller is further configured to—
 cause the pump to provide the hydration fluid at the first flow rate at a first time, such that the patient has a first net fluid loss rate at the first time; and 
 cause the pump to provide the hydration fluid at the second flow rate at a second time different than the first time, such that the patient has a second net fluid loss rate different than the first net fluid loss rate at the second time. 
 
     
     
         30 . The fluid therapy system of  claim 29  wherein the first net fluid loss rate is a first non-zero net fluid loss rate and wherein the second net fluid loss rate is a second non-zero net fluid loss rate. 
     
     
         31 . A fluid therapy method, comprising:
 obtaining a urine output rate of the patient;   after obtaining the urine output rate, causing a hydration fluid to be provided via a pump to the patient at a first flow rate; and   after causing the hydration fluid to be provided at the first flow rate, causing the hydration fluid to be provided via the pump at a second flow rate different than the first flow rate, such that a net fluid loss from the patient increases as the urine output rate of the patient increases.   
     
     
         32 . The fluid therapy method of  claim 31  wherein causing the hydration fluid to be provided at the second flow rate includes causing the hydration fluid to be provided at a rate less than the urine output rate. 
     
     
         33 . The fluid therapy method of  claim 31 , further comprising receiving an indication that at least one of (i) a predetermined volumetric amount of urine output has been reached, or (ii) a predetermined amount of time has elapsed, wherein causing the hydration fluid to be provided at the second flow rate occurs after receiving the indication. 
     
     
         34 . The fluid therapy method of  claim 31  further comprising:
 determining the first flow rate based at least partially on the urine output rate of the patient at a first time; and 
 determining the second flow rate based at least partially on the urine output rate at a second time after the first time. 
 
     
     
         35 . The fluid therapy method of  claim 31  further comprising obtaining a net fluid loss rate of the patient based at least partially on the measured urine output, wherein causing the hydration fluid to be provided at the second flow rate includes increasing the net fluid loss rate of the patient. 
     
     
         36 . The fluid therapy method of  claim 31  wherein:
 causing the hydration fluid to be provided at the first flow rate occurs at a first time when the patient has a first net fluid loss rate; and 
 causing the hydration fluid to be provided at the second flow rate occurs at a second time different than the first time when the patient has a second net fluid loss rate different than the first net fluid loss rate. 
 
     
     
         37 . The fluid therapy method of  claim 36  wherein causing the pump to provide the hydration fluid at the second flow rate includes causing an increase in the patient's net fluid loss rate from the first net fluid loss rate to the second net fluid loss rate. 
     
     
         38 . A non-transitory computer-readable medium having instructions that, when executed by one or more processors of a fluid therapy console, cause the fluid therapy console to perform operations comprising:
 obtaining, via a urine measurement device of the fluid therapy console, a urine output rate of a patient based at least partially on a measured urine output from the urine measurement device,   after obtaining the urine output rate, delivering, via a pump of the fluid therapy console, hydration fluid to the patient at a first flow rate, and   after delivering the hydration fluid at the first flow rate, delivering the hydration fluid to the patient at a second flow rate different than the first flow rate, such that a net fluid loss from the patient increases as the urine output rate of the patient increases.   
     
     
         39 . The non-transitory computer-readable medium of  claim 38  wherein delivering the hydration fluid at the second flow rate includes delivering the hydration fluid at a rate less than the urine output rate. 
     
     
         40 . The non-transitory computer-readable medium of  claim 38 , the operations further comprising:
 determining the first flow rate based at least partially on the urine output rate of the patient at a first time; and   determining the second flow rate based at least partially on the urine output rate at a second time after the first time.   
     
     
         41 . The non-transitory computer-readable medium of  claim 38 , the operations further comprising, based at least partially on the measured urine output from the urine measurement device, determining a net fluid loss rate of the patient, wherein delivering the hydration fluid at the second flow rate includes causing an increase in the patient's net fluid loss rate. 
     
     
         42 . The non-transitory computer-readable medium of  claim 38 , the operations further comprising receiving an indication that a predetermined volumetric threshold of urine output has been reached, wherein delivering the hydration fluid to the patient at the second flow rate occurs after receiving the indication. 
     
     
         43 . The non-transitory computer-readable medium of  claim 38 , wherein delivering the hydration fluid at the first rate occurs at a first time, the operations further comprising receiving an indication that a predetermined amount of time has elapsed since the first time, and wherein delivering the hydration fluid to the patient at the second flow rate occurs after receiving the indication.