US2022168354A1PendingUtilityA1

Compositions Comprising Milk Fat Globules

61
Individually held — no corporate assignee on recordPriority: Apr 16, 2020Filed: Feb 16, 2022Published: Jun 2, 2022
Est. expiryApr 16, 2040(~13.7 yrs left)· nominal 20-yr term from priority
Inventors:James Kane
A61K 35/20A61K 9/0014A61K 9/14A61K 9/006A61K 9/0053A61K 9/06A61K 47/06
61
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Claims

Abstract

Compositions including anti-viral compositions, therapeutic compositions, sunscreen compositions, skin treatment compositions, and anti-aging compositions, are provided. Each composition includes milk fat globules (MFG) and may contain one or more agents encapsulated by the MFG. The unique nature of MFG provides an intact mammalian membrane containing proteins, glycoproteins, and carbohydrates found in mammary cells. MFG derived from mammals can be used to deliver pharmaceutical materials into an animal body such that the pharmaceutical materials bypass the venous blood and enter directly into the animal's lymphatic system. MFG allow the delivery of materials orally that could not heretofore have been delivered efficiently.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A gargle composition comprising milk fat globules from a processed mammalian milk source, and a liquid carrier, the liquid carrier being selected from the group consisting of water, milk, fruit juice, a sugar solution, a sports drink, tea, chilled coffee, a mouth wash, and an ethanol-based liquid, wherein the gargle composition comprises the milk fat globules in an amount of from 16% by weight to 80% by weight, based on the total weight of the gargle composition, and the milk fat globules comprise an organized mammalian membrane containing glycoproteins and ACE-2 protein. 
     
     
         2 . The gargle composition of  claim 1 , wherein the gargle composition is contained in a spray bottle. 
     
     
         3 . The gargle composition of  claim 1 , wherein the composition is in the form of a sprayable liquid and is contained in a spray bottle that has a spray nozzle. 
     
     
         4 . The gargle composition of  claim 1 , wherein the composition is in the form of a sprayable liquid and is contained in a pressurized spray bottle. 
     
     
         5 . The gargle composition of  claim 1 , consisting of the milk fat globules processed from a mammalian milk source, and the liquid carrier. 
     
     
         6 . A composition comprising milk fat globules processed from a mammalian milk source, and a pharmaceutically acceptable topical carrier, wherein the composition comprises from 10% by weight to 95% by weight milk fat globules based on the total weight of the composition, the composition comprises from 5% by weight to 90% by weight the pharmaceutically acceptable topical carrier, based on the total weight of the composition, the milk fat globules comprise an organized mammalian membrane containing glycoproteins, and the pharmaceutically acceptable topical carrier comprises petrolatum, paraben, mineral oil, hemp oil, full spectrum hemp oil, broad spectrum hemp oil, CBD, purified CBD, full spectrum hemp oil with CBDA/CBD at about a 1:1 ratio, beeswax, vitamin A, vitamin D, vitamin E, or a combination thereof. 
     
     
         7 . The composition of  claim 6 , wherein the composition comprises from 25% by weight to 75% by weight milk fat globules, based on the total weight of the composition. 
     
     
         8 . The composition of  claim 6 , wherein the pharmaceutically acceptable topical carrier is petrolatum. 
     
     
         9 . The composition of  claim 6 , wherein the composition comprises from 40% by weight to 60% by weight milk fat globules, based on the total weight of the composition, and from 60% by weight to 40% by weight the pharmaceutically acceptable topical carrier. 
     
     
         10 . The composition of  claim 6 , wherein the composition is in the form of a lip balm, and the pharmaceutically acceptable carrier comprises petrolatum. 
     
     
         11 . The composition of  claim 6 , wherein the pharmaceutically acceptable carrier comprises petrolatum. 
     
     
         12 . The composition of  claim 6 , wherein the composition is in the form of a salve. 
     
     
         13 . The composition of  claim 6 , consisting of the milk fat globules processed from a mammalian milk source, and the pharmaceutically acceptable topical carrier. 
     
     
         14 . The composition of  claim 6 , further comprising a sunscreen agent selected from the group consisting of avobenzone, homosalate, octisalate, octocrylene, oxybenzone, eumelanin, pheomelanin, vitamin C, glutathione, melatonin, a carotenoid, a flavonoid, uric acid, selenium, and resveratrol. 
     
     
         15 . The composition of  claim 6 , further comprising a sunscreen agent selected from the group consisting of avobenzone present in an amount of 2.7% by weight, based on the total weight of the composition, homosalate present in an amount of 4% by weight, based on the total weight of the composition, octisalate present in an amount of 4.5% by weight, based on the total weight of the composition, octocrylene present in an amount of 6% by weight, based on the total weight of the composition, and oxybenzone present in an amount of 4.5% by weight, based on the total weight of the composition. 
     
     
         16 . The composition of  claim 6 , further comprising one or more retinoids. 
     
     
         17 . The composition of  claim 6 , wherein the one or more retinoids comprises one or more of retinol-ester, retinol, retinal, and retinsäure. 
     
     
         18 . The composition of  claim 6 , wherein the pharmaceutically acceptable topical carrier comprises full spectrum hemp oil containing CBDA and CBD. 
     
     
         19 . The composition of  claim 6 , the pharmaceutically acceptable topical carrier comprises at least one of a tocotrienol and a tocopherol. 
     
     
         20 . The composition of  claim 6 , wherein the pharmaceutically acceptable topical carrier comprises vitamin D. 
     
     
         21 . The composition of  claim 6 , further comprising melatonin. 
     
     
         22 . The composition of  claim 6 , further comprising resveratrol. 
     
     
         23 . The composition of  claim 6 , further comprising selenium. 
     
     
         24 . The composition of  claim 6 , wherein the pharmaceutically acceptable topical carrier comprises at least melanin and an antioxidant.

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