US2022175971A1PendingUtilityA1

Dye enhanced visualization of cataract surgery

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Assignee: EXCEL LENS INCPriority: Apr 13, 2018Filed: Feb 28, 2022Published: Jun 9, 2022
Est. expiryApr 13, 2038(~11.7 yrs left)· nominal 20-yr term from priority
Inventors:David H. Mordaunt
A61B 34/30A61K 49/0071A61K 49/006A61B 2218/007A61K 9/0048A61F 9/008A61K 9/08A61B 2218/002A61F 2009/00887A61F 2009/00889A61F 2009/0087A61F 2/1662
70
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Cited by
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Claims

Abstract

The invention relates generally to the use of dyes to enhance visualization of tissues and boundaries of openings in tissues during cataract surgery.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . An ophthalmic solution comprising an isotonic and pH neutral aqueous solution of Trypan Blue at a concentration greater than or equal to 0.3% and less than or equal to 0.45% by weight packaged in a syringe. 
     
     
         2 . The ophthalmic solution of  claim 1 , comprising one or more other dyes that absorb in the red and orange region of the spectrum. 
     
     
         3 . The ophthalmic solution of  claim 2 , wherein the one or more other dyes comprise Evans Blue. 
     
     
         4 . The ophthalmic solution of  claim 2 , wherein the concentration by weight of Trypan Blue is equal to or about equal to the total concentration by weight of the one or more other dyes. 
     
     
         5 . The ophthalmic solution of  claim 2 , wherein the total concentration by weight of Trypan Blue and the one or more other dyes is greater than 0.3% and less than or equal to 0.45% by weight. 
     
     
         6 . The ophthalmic solution of  claim 5 , wherein the one or more other dyes comprise Evans Blue. 
     
     
         7 . The ophthalmic solution of  claim 6 , wherein the concentrations by weight of Trypan Blue and Evans Blue are equal or about equal. 
     
     
         8 . An ophthalmic solution comprising an isotonic and pH neutral aqueous solution of Trypan Blue at a concentration greater than or equal to 0.3% and less than or equal to 0.45% by weight packaged in a delivery device configured to introduce the ophthalmic solution into the anterior chamber of an eye and apply it to the anterior lens capsule in the eye. 
     
     
         9 . The ophthalmic solution of  claim 8 , comprising one or more other dyes that absorb in the red and orange region of the spectrum. 
     
     
         10 . The ophthalmic solution of  claim 9 , wherein the one or more other dyes comprise Evans Blue. 
     
     
         11 . The ophthalmic solution of  claim 9 , wherein the concentration by weight of Trypan Blue is equal to or about equal to the total concentration by weight of the one or more other dyes. 
     
     
         12 . The ophthalmic solution of  claim 9 , wherein the total concentration by weight of Trypan Blue and the one or more other dyes is greater than 0.3% and less than or equal to 0.45% by weight. 
     
     
         13 . The ophthalmic solution of  claim 12 , wherein the one or more other dyes comprise Evans Blue. 
     
     
         14 . The ophthalmic solution of  claim 13 , wherein the concentrations by weight of Trypan Blue and Evans Blue are equal or about equal. 
     
     
         15 . An ophthalmic solution comprising an isotonic and pH neutral aqueous solution of Trypan Blue at a concentration greater than or equal to 0.3% and less than or equal to 0.45% by weight packaged in a delivery device configured to introduce the ophthalmic solution into the anterior chamber of an eye and apply it to lens tissue in the eye. 
     
     
         16 . The ophthalmic solution of  claim 15 , comprising one or more other dyes that absorb in the red and orange region of the spectrum. 
     
     
         17 . The ophthalmic solution of  claim 16 , wherein the one or more other dyes comprise Evans Blue. 
     
     
         18 . The ophthalmic solution of  claim 16 , wherein the concentration by weight of Trypan Blue is equal to or about equal to the total concentration by weight of the one or more other dyes. 
     
     
         19 . The ophthalmic solution of  claim 16 , wherein the total concentration by weight of Trypan Blue and the one or more other dyes is greater than 0.3% and less than or equal to 0.45% by weight. 
     
     
         20 . The ophthalmic solution of  claim 19 , wherein the one or more other dyes comprise Evans Blue. 
     
     
         21 . The ophthalmic solution of  claim 20 , wherein the concentrations by weight of Trypan Blue and Evans Blue are equal or about equal.

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