US2022241298A1PendingUtilityA1
Oral composition of celecoxib for treatment of pain
Est. expiryMay 28, 2035(~8.9 yrs left)· nominal 20-yr term from priority
A61K 47/44A61K 31/635A61K 47/14A61K 9/08A61P 35/00A61K 47/26A61K 47/10A61K 31/415A61P 25/06C07D 231/12A61K 9/107A61K 9/10A61P 19/00A61P 15/00A61P 29/00A61K 9/0095A61K 9/0053A61K 47/24A61P 25/00A61K 47/00A61P 19/02A61P 25/04
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Claims
Abstract
The present invention relates to a stable oral liquid pharmaceutical composition of celecoxib or its pharmaceutically acceptable salts thereof. The celecoxib present in the compositions as described herein do not show any precipitation when subjected in Fasted-State Simulated Gastric Fluid (FaSSGF) at pH 2.0, temperature of 37° C.±0.5° C. and under stirring at a speed of 50 rpm at least for 60 minutes. It also relates to the process of preparing and method of using said composition of celecoxib.
Claims
exact text as granted — not AI-modified1 . A stable oral liquid pharmaceutical composition comprising a therapeutically effective amount of celecoxib, at least one solubilizer, at least one medium chain glyceride, and at least one polar solvent, wherein said composition has a D50 oil droplet size of not more than about 250 nm upon being subjected to stability evaluation conditions of 40° C./75% RH for 3 months.
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