Compositions and methods for inhibiting inflammation and diseases using an alginic acid-based antimicrobial compound

Abstract

The present disclosure relates to compositions and methods for inhibiting inflammation and reducing the risk of spreading sexually transmitted diseases using an alginic acid-based antimicrobial compound. Such compositions provide dual protection by (1) attacking and inactivating viruses and other microbes and (2) blocking the host response that viruses trigger to invade host cells. Such compositions can also be part of an acid buffering contraceptive.

What is claimed is: 
     
         1 . A composition for inhibiting inflammation and disease comprising 1-(6-aminopurin-9-yl)propan-2-yloxymethylphosphonic acid (tenofovir) or a physiologically functional derivative thereof, alginic acid, and an aqueous based carrier;
 wherein the alginic acid has an average molecular weight between 20,000 to 400,000; and   wherein the alginic acid has a ratio of mannuronate:guluronate residues between 0.25 to 2.0.