Drug delivery device with electronics

Abstract

A system may include a mobile application residing on an external device and an inhalation device. The inhalation device may include a mouthpiece, a mouthpiece cover, medicament, and an electronics module comprising a processor. The inhalation device may be configured to both prepare a dose of medicament for delivery to a user and cause the processor to transition between power states when the mouthpiece cover is moved from a closed position to an open position to expose the mouthpiece. The electronics module or the mobile application may be configured to generate usage events based on usage of the inhalation device by the user. The electronics module may also include a pressure sensor, and the electronics module or the mobile application may be configured to determine whether a usage event is a good inhalation event, a fair inhalation event, or a no inhalation event based on feedback from the pressure sensor.

1 . A system comprising:
 an inhalation device comprising:
 a mouthpiece, a mouthpiece cover, medicament, and an air vent, wherein the air vent is configured to allow a flow of air into the inhalation device during a delivery of the medication to a user; and 
 an electronics module comprising a processor, sensor, and wireless communication circuit, wherein the processor of the electronics module is configured to determine an airflow measurement during an inhalation of a dose of medication by the user; and 
   a computer-readable storage medium residing on an external device, wherein the computer-readable storage medium comprises computer-executable instructions that, when executed by a processor of the external device cause the processor of the external device to:   provide a notification to the user of an air vent blockage event indicating that there was a possible blockage of the air vent when the airflow measurement exceeds a threshold.   
     
     
         2 . The system of  claim 1 , wherein the notification comprises the presentation of a message via a display device of the external device. 
     
     
         3 . The system of  claim 1 , wherein, when executed by the processor of the external device, the computer-readable storage medium is configured to cause the processor of the external device to:
 generate a good inhalation event when the airflow measurement is between a lower and upper threshold, and generate the air vent blockage event when the airflow measurement is above the upper threshold.   
     
     
         4 . The system of  claim 1 , wherein the processor of the electronics module is configured to determine a flow rate of the inhalation based on the airflow measurements; and
 wherein, when executed by the processor of the external device, the computer-readable storage medium is configured to cause the processor of the external device to:   determine that the flow rate of the inhalation exceed a flow rate threshold; and   provide the notification to the user of the air vent blockage event in response to the flow rate exceeding the flow rate threshold.   
     
     
         5 . The system of  claim 4 , wherein the flow rate threshold is 200 liters per minute (Lpm). 
     
     
         6 . The system of  claim 1 , wherein the mouthpiece cover is configured to move from a closed position to an open position to expose the mouthpiece;
 wherein the electronics module of the inhalation device is configured to determine that the mouthpiece cover is in the open position for greater than a predetermine amount of time; and   wherein, when executed by the processor of the external device, the computer-readable storage medium is configured to cause the processor of the external device to provide a notification to the user that the mouthpiece cover should be moved to the closed position.   
     
     
         7 . The system of  claim 1 , wherein the mouthpiece cover is configured to move from a closed position to an open position to expose the mouthpiece;
 wherein the electronics module of the inhalation device is configured to determine that feedback from the sensor indicates that there have been multiple inhalation events while the mouthpiece cover is in the open position; and   wherein, when executed by the processor of the external device, the computer-readable storage medium is configured to cause the processor of the external device to provide a notification to the user that the mouthpiece cover needs to be moved to the closed position and then re-opened to ensure that a subsequent dose of medication is made available for inhalation.   
     
     
         8 . A system comprising:
 a computer-readable storage medium residing on an external device; and   an inhalation device comprising:
 a mouthpiece, a mouthpiece cover, and medicament, wherein the mouthpiece cover is configured to move from a closed position to an open position to expose the mouthpiece; and 
 an electronics module comprising a processor, sensor, and wireless communication circuit, wherein the processor of the electronics module is configured to:
 generate a usage event based on movement of the mouthpiece cover from the closed position to the open position or based on feedback from the sensor; and 
 send the usage event to the external device; 
 
   wherein the computer-readable storage medium comprises computer-executable instructions that, when executed by a processor of the external device cause the processor of the external device to:
 receive the usage event from the inhalation device; 
 determine that a number of usage events exceeds a predetermined number of events for a set time period; and 
 provide a notification to the user of an overuse event based on the determination that the number of usage events exceeded the predetermined number for the set time period. 
   
     
     
         9 . The system of  claim 8 , wherein the medicament is a rescue medicament, the set time period is twenty-four-hours, and the predetermined number is eight. 
     
     
         10 . The system of  claim 8 , wherein the medicament is a rescue medicament, the set time period is twenty-four-hours, and the predetermined number is eight. 
     
     
         11 . The system of  claim 8 , wherein the medicament is a maintenance medicament, the set time period is twenty-four-hours, and the predetermined number is two. 
     
     
         12 . The system of  claim 8 , wherein the electronics module of the inhalation device is configured to determine that the mouthpiece cover is in the open position for greater than a predetermine amount of time; and
 wherein, when executed by the processor of the external device, the computer-readable storage medium is configured to cause the processor of the external device to provide a notification to the user that the mouthpiece cover should be closed.   
     
     
         13 . The system of  claim 8 , wherein the electronics module of the inhalation device is configured to determine that feedback from the sensor indicates that there have been multiple inhalation events while the mouthpiece cover is in the open position; and
 wherein, when executed by the processor of the external device, the computer-readable storage medium is configured to cause the processor of the external device to provide a notification to the user that the mouthpiece cover needs to be closed and then re-opened to ensure that a subsequent dose of medication is made available for inhalation.   
     
     
         14 . A system comprising:
 an inhalation device comprising:
 a mouthpiece, a mouthpiece cover, medicament, and an air vent, wherein the mouthpiece cover is configured to move from a closed position to an open position to expose the mouthpiece; and 
 an electronics module comprising a processor, sensor, and wireless communication circuit, wherein the processor of the electronics module is configured to: 
 determine an airflow measurement during an inhalation of a dose of medication by the user; and 
 determine that there have been multiple inhalation events while the mouthpiece cover is in the open position; and 
   a computer-readable storage medium residing on an external device, wherein the computer-readable storage medium comprises computer-executable instructions that, when executed by a processor of the external device cause the processor of the external device to:   provide a notification to the user that the mouthpiece cover needs to be moved to the closed position and then re-opened to ensure that a subsequent dose of medication is made available for inhalation.   
     
     
         15 . The system of  claim 14 , wherein the inhalation device is configured to both prepare a dose of medicament for delivery to the user and cause the processor to transition between power states when the mouthpiece cover is moved from a closed position to an open position to expose the mouthpiece. 
     
     
         16 . The system of  claim 14 , wherein the inhalation device is configured to cause a dose of medicament to be moved from a reservoir into a dosing cup in response to the mouthpiece cover being moved from the closed position to the open position to expose the mouthpiece. 
     
     
         17 . The system of  claim 14 , wherein the inhalation device is configured to open a blister of a blister strip in response to the mouthpiece cover being moved from the closed position to the open position to expose the mouthpiece, wherein each blister of the blister strip comprises a dose of medicament. 
     
     
         18 . The system of  claim 14 , wherein the air vent is configured to allow a flow of air into the inhalation device during a delivery of the medication to a user; and
 wherein the computer-readable storage medium comprises computer-executable instructions that, when executed by a processor of the external device cause the processor of the external device to:   provide a notification to the user of an air vent blockage event indicating that there was a possible blockage of the air vent when the airflow measurement exceeds a threshold.   
     
     
         19 . The system of  claim 14 , wherein the processor of the electronics module is configured to:
 generate a usage event based on movement of the mouthpiece cover from the closed position to the open position or based on feedback from the sensor; and   send the usage event to the external device;   wherein the computer-readable storage medium comprises computer-executable instructions that, when executed by a processor of the external device cause the processor of the external device to:   receive the usage event from the inhalation device;   determine that a number of usage events exceeds a predetermined number of events for a set time period; and   provide a notification to the user of an overuse event based on the determination that the number of usage events exceeded the predetermined number for the set time period.   
     
     
         20 . The system of  claim 14 , wherein the electronics module of the inhalation device is configured to determine that the mouthpiece cover is in an open position for greater than a predetermine amount of time; and
 wherein, when executed by the processor of the external device, the computer-readable storage medium is configured to cause the processor of the external device to provide a notification to the user that the mouthpiece cover should be closed.