Delivery and retrieval devices and methods for side-deliverable transcatheter prosthetic valves

Abstract

A delivery system for side-delivery of a prosthetic valve includes a compression device defining a lumen having a first perimeter at a proximal end that is larger than a second perimeter of the lumen at a distal end. A loading device is coupleable to the compression device and defines a lumen having substantially the second perimeter. A distal end of the loading device includes a first gate that is movable between an open state and a closed state to at least partially occlude the lumen of the loading device. A delivery device defines a lumen having substantially the second perimeter. A proximal end of the delivery device is coupleable to the distal end of the loading device and includes a second gate movable between an open state and a closed state to at least partially occlude the lumen of the delivery device.

1 .- 93 . (canceled) 
     
     
         94 . A delivery and retrieval system for a side-deliverable prosthetic valve, the system comprising:
 a catheter having a distal end and defining a lumen, the prosthetic valve having a delivery configuration for side delivery through the lumen of the catheter and a deployment configuration when released from the distal end of the catheter;   a capture element disposable in the lumen of the catheter in a closed configuration and transitionable to an open configuration when advanced beyond the distal end of the catheter; and   a control device disposable in the lumen of the catheter and configured to attach to the prosthetic valve, the control device operable to (i) exert a distally directed force to advance the prosthetic valve in the delivery configuration through the lumen of the catheter and (ii) exert a proximally directed force to pull the prosthetic valve in the deployment configuration into the distal end of the catheter, the capture element extendable around at least a portion of the prosthetic valve to transition the prosthetic valve from the deployment configuration to the delivery configuration as the control device pulls the prosthetic valve into the distal end of the catheter.   
     
     
         95 . The system of  claim 94 , wherein the capture element is a self-expanding capture element formed from a shape-memory alloy. 
     
     
         96 . The system of  claim 94 , wherein the catheter is an outer catheter, the capture element is mounted at a distal end of an inner catheter movably disposed in the lumen of the catheter. 
     
     
         97 . The system of  claim 94 , wherein the capture element is mounted within the lumen of the catheter and is transitionable to the open configuration by withdrawing a slidable sheath at the distal end of the catheter. 
     
     
         98 . The system of  claim 94 , wherein the capture element is mounted at a distal end portion of the control device. 
     
     
         99 . The system of  claim 94 , wherein the control device includes a yoke configured to removably contact a surface of the prosthetic valve. 
     
     
         100 . A retrieval system for a side-deliverable prosthetic valve, the system comprising:
 a control device removably coupleable to the prosthetic valve during delivery and deployment of the prosthetic valve in an annulus of a native valve; and   a self-expanding capture element that is extendable from a distal end of a delivery catheter to funnel or wrap at least a portion of the prosthetic valve at least partially deployed in an annulus of a native heart valve to facilitate a compression of the prosthetic valve in response to a force exerted by the control device moving the prosthetic valve in a proximal direction toward the delivery catheter.   
     
     
         101 . The system of  claim 100 , wherein the control device includes a yoke configured to removably contact a surface of the prosthetic valve. 
     
     
         102 . The system of  claim 100 , wherein the prosthetic valve has a delivery configuration and a deployment configuration, the compression of the prosthetic valve being operable to at least partially transition the prosthetic valve from the deployment configuration to the delivery configuration. 
     
     
         103 . The system of  claim 102 , wherein the self-expanding capture element facilitates the compression of the prosthetic valve to the delivery configuration such that the force exerted by the control device pulls the prosthetic valve in the delivery configuration into the delivery catheter. 
     
     
         104 . A method of retrieving a side-deliverable prosthetic heart valve, comprising:
 (i) extending a self-expanding capture element from a distal end of a catheter disposed in a native atrium of a heart, the capture element configured to have a cavity shape when in an extended position; and   (ii) pulling the heart valve into the cavity of the extended capture element to facilitate compressing of the heart valve, wherein pulling the heart valve into the capture element transitions the capture element from the extended position to a retracted position, wherein the heart valve is wrapped by the capture element in the retracted position, and wherein the heart valve that is wrapped by the capture element is pulled into the catheter using a cable.   
     
     
         105 . The method of  claim 104 , wherein the valve is pre-compressed by (a) suturing the proximal tab against the underside of the atrial collar, or (b) pinching the proximal sidewall hips, or (c) both, prior to pulling the heart valve into the cavity. 
     
     
         106 . The method of  claim 105 , wherein a yoke element on the cable is used to suture the proximal tab, pinch the sidewall hips, or both.