US2022280535A1PendingUtilityA1

Methods for inhibiting muscle atrophy

Assignee: UNIV IOWA RES FOUNDPriority: May 20, 2010Filed: May 17, 2021Published: Sep 8, 2022
Est. expiryMay 20, 2030(~3.8 yrs left)· nominal 20-yr term from priority
A61P 21/00A61K 31/353A61K 31/473G01N 2800/52G01N 33/5023A61K 31/4164A61K 31/4706A61K 31/382A61K 31/4365A61K 31/4355A61K 31/565A61K 31/404A61K 31/4166C12Q 1/6809A61K 31/58A61K 31/215A61K 31/407A61K 31/438A61K 31/436A61K 31/56A61K 31/437A61K 31/4375A61K 31/36G01N 2800/10A61K 31/435C12Q 2600/136A61K 31/352
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Claims

Abstract

The invention provides a method for (a) increasing skeletal muscle mass; (b) reducing skeletal muscle atrophy; (c) increasing muscular strength; (d) promoting muscle growth; (e) decreasing muscle wasting; or (f) increasing strength per unit of muscle mass in an animal identified or having been identified to be in need of one or more of (a)-(f), the method comprising administering to the animal an effective amount of a compound of formula:or a stereoisomer, solvate, or pharmaceutically acceptable salt thereof, thereby accomplishing one or more of (a)-(f).

Claims

exact text as granted — not AI-modified
1 . A method for:
 (a) increasing skeletal muscle mass;   (b) reducing skeletal muscle atrophy;   (c) increasing muscular strength;   (d) promoting muscle growth;   (e) decreasing muscle wasting; or   (f) increasing strength per unit of muscle mass   
       in an animal identified or having been identified to be in need of one or more of (a)-(f), the method comprising administering to the animal an effective amount of a compound of formula: 
       
         
           
           
               
               
           
         
       
       or a stereoisomer, solvate, or pharmaceutically acceptable salt thereof, thereby accomplishing one or more of (a)-(f).

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