Sensor arrays with nucleophilic indicators

Abstract

Sensors arrays that include indicators arranged in a pattern on a substrate. The indicators include nucleophilic indicators. In some examples, the sensor arrays with multiple nucleophilic indicators provide superior detection and identification of microorganisms, cancer biomarkers, formaldehyde, organophosphates, and aldehydes.

1 - 18 . (canceled) 
     
     
         19 . A method for determining if a patient has a malady, the method comprising:
 providing a sensor array comprising a first indicator and a second indicator deposited on a substrate in a predetermined pattern wherein the first and second indicators are nucleophilic indicators;   exposing the sensor array to a sample from a patient;   detecting a spectral response after exposing the sensor array to the sample and correlating the spectral response to the presence of a malady.   
     
     
         20 . The method of claim  0  wherein the malady is cancer. 
     
     
         21 . The method of claim  0  wherein the malady is colon cancer. 
     
     
         22 . The method of claim  0  wherein the malady is sepsis. 
     
     
         23 . The method of claim  0  wherein the sample is the exhaled breath of a patient. 
     
     
         24 . The method of claim  0  wherein the sample is a urine sample. 
     
     
         25 . The method of claim  0  wherein exposing the sensor array to a sample from the patient comprises exposing the sensor array to headspace gas of a blood sample.