Delivery guide wire and therapeutic device

Abstract

A delivery guide wire (10,100) and a therapeutic device are disclosed. The therapeutic device includes the delivery guide wire (10, 100), a medical implant and a delivery catheter (20). The delivery guide wire (10, 100) includes a core shaft (110) and a driving member (120) disposed on the core shaft (110), and the driving member (120) defines thereon a depression. The medical implant is compressed by the delivery catheter (20) and disposed over the delivery guide wire (10,100) in such a manner that it is at least partially received in the depression. This results in an increased contact area between the medical implant and the delivery guide wire (10, 100), which facilitates movement of the medical implant in sync with the delivery guide wire (10, 100) and makes its delivery easier.

1 . A delivery guide wire, for delivering a medical implant, wherein the delivery guide wire comprises a core shaft and a driving member on the core shaft, a depression is defined on the driving member. 
     
     
         2 . The delivery guide wire according to  claim 1 , wherein the driving member comprises a body and a recess formed in an outer surface of the body, and the recess forms the depression. 
     
     
         3 . The delivery guide wire according to  claim 2 , wherein the recess has a structure matching at least a part of a structure of the medical implant when the medical implant is in a crimped configuration. 
     
     
         4 . The delivery guide wire according to  claim 3 , wherein the recess is mirrored to an inner surface of the medical implant in the crimped configuration; or
 wherein the recess has a width ranging from 0.0008 inches to 0.004 inches, and/or the recess has a depth ranging from 0.0002 inches to 0.004 inches.   
     
     
         5 . (canceled) 
     
     
         6 . The delivery guide wire according to  claim 2 , wherein the recess comprises one recessed element or a plurality of recessed elements which are interlaced or continuous with, or spaced apart from, one other across the outer surface of the body; or
 wherein the recess helically extends in the outer surface of the body about an axis thereof to form one or more helical grooves.   
     
     
         7 . (canceled) 
     
     
         8 . The delivery guide wire according to  claim 1 , wherein the driving member comprises a wound wire which helically extends about an axis of the core shaft to form one or more helices, and adjacent turns of the wound wire spaced apart to form the depression;
 wherein the wound wire is a polymeric wire or a metal wire coated on a surface thereof with a polymeric coating;   wherein the metal wire is visualizable, and/or the metal wire is a platinum-tungsten alloy wire or a platinum-iridium alloy wire.   
     
     
         9 . (canceled) 
     
     
         10 . (canceled) 
     
     
         11 . The delivery guide wire according to  claim 1 , wherein the driving member comprises an inner piece and an outer piece,
 wherein the inner piece is made of a metallic material and fixedly sleeved over the core shaft, and   the outer piece is made of a polymeric material and fixedly sleeved over the inner piece.   
     
     
         12 . The delivery guide wire according to  claim 11 , wherein the inner piece defines an interspace which is partially or entirely filled by the outer piece, and wherein at least a part of the outer piece goes through the interspace to connect to the core shaft; or
 wherein the inner piece has an outer surface provided therein with a recess which forms the interspace; or   wherein the inner piece comprises a plurality of coils which are arranged along an axis of the core shaft, and the interspace is formed between adjacent ones of the coils.   
     
     
         13 . (canceled) 
     
     
         14 . (canceled) 
     
     
         15 . The delivery guide wire according to  claim 11 , wherein the inner piece is a meshed tubular structure braided from a wire, and openings in the meshed tubular structure form the interspace;
 wherein the wire has a diameter of 0.001 inch or less, and/or each inch of the inner piece contains 15-50 braid knots.   
     
     
         16 . (canceled) 
     
     
         17 . The delivery guide wire according to  claim 11 , wherein the inner piece comprises at least one tubular element and is partially or entirely wrapped by the outer piece. 
     
     
         18 . The delivery guide wire according to  claim 11 , wherein the inner piece is a helix formed by a wire extending helically about an axis of the core shaft, and the interspace is formed between adjacent turns of the wire;
 wherein the wire has a diameter of 0.001 inch or less, and/or the helix formed by the wire has a pitch of 0.001-0.007 inches.   
     
     
         19 . (canceled) 
     
     
         20 . The delivery guide wire according to  claim 1 , wherein the inner piece is made of a visualizable metallic material selected from one or more of platinum, gold, tungsten, a platinum-gold alloy, a platinum-tungsten alloy, a platinum-iridium alloy and a platinum-nickel alloy;
 and/or   wherein the inner piece is welded or glued to the core shaft, and/or the outer piece wraps the inner piece and extends to connect to the core shaft.   
     
     
         21 . (canceled) 
     
     
         22 . The delivery guide wire according to  claim 11 , wherein the outer piece is made of a material comprising one or more of a block polyether amide resin, a thermoplastic polyurethane elastomer, silicone, nylon and an acrylic polymer;
 and/or   wherein the outer piece is formed on the inner piece by hot pressing and/or dipping, or the inner piece is adhesively bonded to the outer piece;   wherein the recess is formed in an outer surface of the outer piece, and/or the recess has a structure matches at least a part of a structure of the medical implant when the medical implant is in a crimped configuration; wherein the recess comprises one recessed element or a plurality of recessed elements which are interlaced or continuous with, or spaced apart from, one other across an outer surface of the body.   
     
     
         23 . (canceled) 
     
     
         24 . (canceled) 
     
     
         25 . (canceled) 
     
     
         26 . The delivery guide wire according to  claim 1 , wherein at least two of the driving members are provided on the core shaft and are spaced apart along an axis of the core shaft, and wherein adjacent ones of the driving members are spaced apart by a distance ranging from 0.5 mm to 150 mm. 
     
     
         27 . (canceled) 
     
     
         28 . The delivery guide wire according to  claim 26 , wherein adjacent ones of the driving members are spaced apart by a distance ranging from 0.5 mm to 5 mm. 
     
     
         29 . The delivery guide wire according to  claim 1 , wherein one or more of the driving members are provided on the core shaft, and each of the driving members has an outer diameter of 0.01-0.03 inches and a length of 0.5-8 mm. 
     
     
         30 . The delivery guide wire according to  claim 29 , wherein the length of each of the driving member ranges from 0.5 mm to 4 mm. 
     
     
         31 . The delivery guide wire according to  claim 1 , further comprising a first visualization member and a second visualization member, the first visualization member disposed at a distal end of the core shaft, the second visualization member disposed on the core shaft, wherein the driving member is situated between the first visualization member and the second visualization member. 
     
     
         32 . A therapeutic device, comprising a delivery catheter, a medical implant and the delivery guide wire according to  claim 1 , wherein the delivery catheter defines a lumen extending therethrough axially, the lumen is configured to receive the medical implant therein so that the medical implant is compressed against a wall of the lumen to become a crimped configuration where the medical implant is sleeved over the driving member so as to be at least partially received in the depression. 
     
     
         33 . The therapeutic device according to  claim 32 , wherein the lumen has a radial size ranging from 0.017 inches to 0.029 inches; and/or
 wherein the medical implant is a self-expanding stent.   
     
     
         34 . (canceled)