US2022409657A1PendingUtilityA1

Instructions for composition and sensitivity

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Assignee: AZURA OPHTHALMICS LTDPriority: Jan 10, 2020Filed: Jul 8, 2022Published: Dec 29, 2022
Est. expiryJan 10, 2040(~13.5 yrs left)· nominal 20-yr term from priority
A61K 9/0048A61K 33/04A61K 9/06A61K 9/0014A61P 27/02A61K 47/36A61K 45/06
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Claims

Abstract

Provided herein are methods treating a disease or disorder in or around the eye with a pharmaceutical composition comprising selenium disulfide (SeS2) and instructing the treated individual to limit or avoid exposure to light following administration in order to reduce the adverse effect of the composition.

Claims

exact text as granted — not AI-modified
1 - 45 . (canceled) 
     
     
         46 . A kit for treating a disease or disorder in or around the eye in an individual in need thereof, the kit comprising:
 a pharmaceutical composition comprising a therapeutically effective amount of selenium disulfide (SeS 2 ); and   instructions for administering a therapeutically effective amount of the pharmaceutical composition to an ocular surface, surrounding ocular tissues, or a combination thereof of the individual before bedtime.   
     
     
         47 . A method for treating a disease or disorder in or around the eye in an individual in need thereof, the method comprising:
 administering a therapeutically effective amount of a pharmaceutical composition to an ocular surface, surrounding ocular tissues, or a combination thereof of the individual;   wherein the pharmaceutical composition comprises a therapeutically effective amount of selenium disulfide (SeS 2 ); and   wherein the pharmaceutical composition is administered before bedtime.   
     
     
         48 . A method for treating a disease or disorder in or around the eye in an individual in need thereof, the method comprising:
 protecting an ocular surface of the individual with a barrier; and   administering a therapeutically effective amount of a pharmaceutical composition to the ocular surface of the individual, wherein the pharmaceutical composition comprises a therapeutically effective amount of selenium disulfide (SeS 2 ).

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