US2022411425A1PendingUtilityA1

Compounds useful in hiv therapy

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Assignee: GLAXOSMITHKLINE IP DEV LTDPriority: Mar 6, 2019Filed: Jun 1, 2021Published: Dec 29, 2022
Est. expiryMar 6, 2039(~12.6 yrs left)· nominal 20-yr term from priority
Inventors:Martha Alicia De La RosaJohn Franklin MillerB. Narasimhulu NaiduVicente SamanoDavid TemelkoffEmile Johann Velthuisen
A61K 45/06A61K 31/70C07H 19/16C07H 19/173C07D 473/34A61K 9/0019A61P 31/18A61K 31/7076C07D 487/04
69
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Claims

Abstract

The invention relates to a compound having the structure: or a pharmaceutically acceptable salt thereof, along with pharmaceutical compositions and therapeutic methods thereof.

Claims

exact text as granted — not AI-modified
1 - 32 . (canceled) 
     
     
         33 . A compound having the structure: 
       
         
           
           
               
               
           
         
         or a pharmaceutically acceptable salt thereof. 
       
     
     
         34 . A pharmaceutical composition comprising a compound according to claim  32 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient. 
     
     
         35 . The composition of  claim 34 , wherein the composition is present in parenteral form. 
     
     
         36 . The composition of  claim 34 , wherein the composition is in a tablet form. 
     
     
         37 . The composition of  claim 34 , wherein the composition is formulated as a long acting parenteral injection. 
     
     
         38 . A method of treating an HIV infection in a patient comprising administering to the subject a compound of  claim 33 , or a pharmaceutically acceptable salt thereof. 
     
     
         39 . A compound having the structure: 
       
         
           
           
               
               
           
         
       
     
     
         40 . A pharmaceutical composition comprising a compound according to  claim 39 , and a pharmaceutically acceptable excipient. 
     
     
         41 . The composition of  claim 40 , wherein the composition is present in parenteral form. 
     
     
         42 . The composition of  claim 40 , wherein the composition is in a tablet form. 
     
     
         43 . The composition of  claim 40 , wherein the composition is formulated as a long acting parenteral injection. 
     
     
         44 . A method of treating an HIV infection in a patient comprising administering to the subject a compound of  claim 39 .

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