Method and arrangement for filling a sterile container

Abstract

Method for filling a sterile container, in particular a bottle, with a liquid, wherein a sterile connection is established between a flexible bag and a first opening of the container, a sterile connection is established between a second opening of the container and a source of the liquid to be filled into the container, the liquid is filled into the container, a gas, in particular air, which is present in the container is displaced by the liquid and forced into the flexible bag while increasing the volume of the flexible bag and the connection between the source of liquid and the second opening of the container is severed in a sterile way.

1 . Method for filling a sterile container, in particular a bottle, with a liquid ( 2 ), wherein
 a sterile connection is established between a flexible bag and a first opening of the container,   a sterile connection is established between a second opening of the container and a source of the liquid to be filled into the container,   the liquid is filled into the container,   a gas, in particular air, which is present in the container is displaced by the liquid and forced into the flexible bag while increasing the volume of the flexible bag and   the connection between the source of liquid and the second opening of the container is severed in a sterile way.   
     
     
         2 . The method according to  claim 1 , wherein the connection between the flexible bag and the first opening of the container is severed in a sterile way. 
     
     
         3 . The method according to  claim 1 , wherein for the connection between the flexible bag and the first opening of the container tubing and/or a sterile connector is used. 
     
     
         4 . The method according to  claim 1 , wherein for the connection between the second opening and the source of liquid tubing and/or a sterile connector is used. 
     
     
         5 . The method according to  claim 1 , wherein the connection between the first opening of the container and the flexible bag or the connection between the second opening of the container and the source of liquid is severed by fusing and/or welding shut tubing and/or decoupling a sterile connector. 
     
     
         6 . Arrangement for filling a sterile container, in particular a bottle, comprising the sterile container and a sterile flexible bag, wherein
 the flexible bag is in fluid communication with the container via a first opening of the container,   the container comprises a second opening and a sealed connecting device for connecting in a sterile way the container to a source of liquid to be filled into the container.   
     
     
         7 . The arrangement according to  claim 6 , wherein the sealed connecting device is a sterile connector.