US2023064711A1PendingUtilityA1

Compositions, kits and methods for enhancing therapeutic compliance

Assignee: BELKIN MICHAELPriority: Dec 30, 2019Filed: Dec 30, 2020Published: Mar 2, 2023
Est. expiryDec 30, 2039(~13.4 yrs left)· nominal 20-yr term from priority
Inventors:Michael Belkin
A61K 47/40A61K 47/10A61K 31/27A61K 31/4178A61K 47/36A61K 9/5153A61K 45/06A61K 31/5575A61K 47/38A61K 9/127A61K 9/0048A61K 47/28A61K 31/4409A61K 9/1647A61K 31/137A61K 47/186A61K 31/439A61P 27/06A61K 9/08A61K 47/06A61K 47/183A61K 47/32A61K 47/34
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Claims

Abstract

The present disclosure encompasses pharmaceutical composition, kits and methods for enhancing therapeutic compliance.

Claims

exact text as granted — not AI-modified
1 - 33 . (canceled) 
     
     
         34 . A pharmaceutical composition comprising:
 (i) a prostaglandin analogue (PGA), or a pharmaceutically acceptable salt thereof, solvate thereof, hydrate thereof, any stereoisomer therefore, physiologically functional derivative thereof; and   (ii) between about 0.1% w/w to about 3% w/w pilocarpine, or a pharmaceutically acceptable salt thereof, solvate thereof, hydrate thereof, stereoisomer thereof, or physiologically functional derivative thereof.   
     
     
         35 . The pharmaceutical composition of  claim 34 , comprising between about 0.1% w/w to about 1% w/w pilocarpine, or a pharmaceutically acceptable salt thereof, solvate thereof, hydrate thereof, stereoisomer thereof, or physiologically functional derivative thereof. 
     
     
         36 . The pharmaceutical composition of  claim 34 , wherein the PGA is latanoprost, or a pharmaceutically acceptable salt thereof, solvate thereof, hydrate thereof, any stereoisomer therefore, physiologically functional derivative thereof. 
     
     
         37 . The pharmaceutical composition of  claim 36 , comprising from 0.005% w/w to 2% w/w latanoprost. 
     
     
         38 . The pharmaceutical composition of  claim 34 , further comprising a carrier, excipient or additive. 
     
     
         39 . The pharmaceutical composition of  claim 34 , wherein the pharmaceutical composition is an ophthalmic ointment. 
     
     
         40 . A method of reducing intra-ocular pressure in an individual in need thereof, the method comprising administering to the individual the pharmaceutical composition of  claim 34 . 
     
     
         41 . A method of treating glaucoma in an individual in need thereof, the method comprising administering to the individual the pharmaceutical composition of  claim 34 . 
     
     
         42 . A method of treating presbyopia in an individual in need thereof, the method comprising administering to the individual the pharmaceutical composition of  claim 34 .

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