US2023106036A1PendingUtilityA1

Method and apparatus for reconstructing electrocardiogram (ecg) data

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Assignee: HEARTBEAM INCPriority: Oct 5, 2021Filed: Sep 19, 2022Published: Apr 6, 2023
Est. expiryOct 5, 2041(~15.2 yrs left)· nominal 20-yr term from priority
Inventors:Petra BelicevBosko BojovicLjupco HadzievskiBranislav VajdicVladimir AtanasoskiGoran GligoricMarjan Miletic
A61B 5/332A61B 5/339A61B 5/327Y02A90/10A61B 5/28A61B 5/7253A61B 5/308
59
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Claims

Abstract

Systems and apparatus for synthesizing (generating) 12-lead ECG dataset from 3-lead ECG data. In particular, one or more transformation parameters may be determined that may be applied to 3-lead ECG dataset to generate 12-lead ECG data with particular speed and accuracy. The transformation parameters, which may include a plurality of matrices, may be determined from a synchronized patient's 12-lead ECG dataset and 3-lead ECG data. The 12-lead ECG dataset may be collected at a different time than the 3-lead ECG data. In some embodiments, the 12-lead ECG dataset and/or the 3-lead ECG dataset may be resampled prior to determining the transformation parameters.

Claims

exact text as granted — not AI-modified
What is claimed is: 
     
         1 . A method of synthesizing 12-lead electrocardiogram (ECG) data, the method comprising:
 receiving a first 12-lead ECG dataset for a patient associated with a first dataset collection time;   receiving a first 3-lead ECG dataset for the patient associated with a second dataset collection time different than the first dataset collection time;   determining a set of linear transformation parameters to synthesize a second 12-lead ECG dataset based at least in part on the first 12-lead ECG dataset and the first 3-lead ECG data; and   synthesizing the second 12-lead ECG dataset from a second 3-lead ECG dataset associated with a third collection time based at least in part on the set of linear transformation parameters.   
     
     
         2 . The method of  claim 1 , wherein the second dataset collection time is separated from first dataset collection time by more than an hour. 
     
     
         3 . The method of  claim 1 , wherein the second dataset collection time is separated from first dataset collection time by more than a day. 
     
     
         4 . The method of  claim 1 , wherein the first 3-lead ECG dataset comprises three orthogonal or pseudo-orthogonal leads. 
     
     
         5 . The method of  claim 1 , wherein the first 3-lead ECG dataset is synchronized with the first 12-lead ECG dataset by determining a representative beat for both the first 3-lead ECG dataset and the first 12-lead ECG dataset. 
     
     
         6 . The method of  claim 1 , wherein the first 3-lead ECG dataset is synchronized with the second 12-lead ECG dataset by further resampling at least one of the first 12-lead ECG dataset and the first 3-lead ECG dataset. 
     
     
         7 . The method of  claim 6 , wherein the resampling is in a frequency domain. 
     
     
         8 . The method of  claim 1 , wherein the first 3-lead ECG dataset is synchronized with the first 12-lead ECG dataset by determining a cross-correlation between the first 3-lead ECG dataset and the first 12-lead ECG dataset. 
     
     
         9 . The method of  claim 1 , wherein the first 3-lead ECG dataset is synchronized with the first 12-lead ECG dataset by further aligning features of a QRS complex of the first 12-lead ECG dataset with features of a QRS complex of the first 3-lead ECG dataset. 
     
     
         10 . The method of  claim 1 , wherein the first 3-lead ECG dataset is synchronized with the first 12-lead ECG dataset by further determining a representative beat for both the first 3-lead ECG dataset and the first 12-lead ECG dataset based on a median beat or an average beat from a plurality of heartbeats. 
     
     
         11 . The method of  claim 1 , wherein the first 3-lead ECG dataset is synchronized with the first 12-lead ECG dataset by further determining a representative beat for both the first 3-lead ECG dataset and the first 12-lead ECG dataset by selecting a median heartbeat from each of the first 12-lead ECG dataset and the first 3-lead ECG dataset. 
     
     
         12 . The method of  claim 1 , wherein the set of linear transformation parameters comprises a set of transformation matrices that synthesize the first 12-lead ECG dataset from the first 3-lead ECG dataset. 
     
     
         13 . The method of  claim 1 , further comprising outputting the second 12-lead ECG dataset. 
     
     
         14 . The method of  claim 13 , wherein outputting the second 12-lead ECG dataset comprises displaying the second 12-lead ECG dataset. 
     
     
         15 . An electrocardiogram (ECG) system comprising:
 a portable ECG device configured to record a current 3-lead ECG dataset from a patient; and   a non-transitory computer-readable storage medium comprising instructions that, when executed by one or more processors, cause the one or more processors to perform operations comprising:
 receiving a first 12-lead ECG dataset for a patient associated with a first dataset collection time; 
 receiving a first 3-lead ECG dataset for the patient associated with a second dataset collection time different than the first dataset collection time; 
 determining a set of linear transformation parameters to synthesize a second 12-lead ECG dataset based at least in part on the first 12-lead ECG dataset and the first 3-lead ECG data; 
 synthesizing the second 12-lead ECG dataset from a second 3-lead ECG dataset associated with a third collection time based at least in part on the set of linear transformation parameters; and 
 outputting the second 12-lead ECG dataset. 
   
     
     
         16 . The system of  claim 15 , wherein the second dataset collection time is separated from first dataset collection time by more than an hour. 
     
     
         17 . The system of  claim 15 , wherein the second dataset collection time is separated from first dataset collection time by more than a day. 
     
     
         18 . The system of  claim 15 , wherein the first 3-lead ECG dataset comprises three orthogonal or pseudo-orthogonal leads. 
     
     
         19 . The system of  claim 15 , wherein the first 3-lead ECG dataset is synchronized with the first 12-lead ECG dataset by determining a representative beat for both the first 3-lead ECG dataset and the first 12-lead ECG dataset. 
     
     
         20 . The system of  claim 15 , wherein the first 3-lead ECG dataset is synchronized with the second 12-lead ECG dataset by further resampling at least one of the first 12-lead ECG dataset and the first 3-lead ECG dataset. 
     
     
         21 . The system of  claim 20 , wherein the resampling is in a frequency domain. 
     
     
         22 . The system of  claim 15 , wherein the first 3-lead ECG dataset is synchronized with the first 12-lead ECG dataset by determining a cross-correlation between the first 3-lead ECG dataset and the first 12-lead ECG dataset. 
     
     
         23 . The system of  claim 15 , wherein the first 3-lead ECG dataset is synchronized with the first 12-lead ECG dataset by further aligning features of a QRS complex of the first 12-lead ECG dataset with features of a QRS complex of the first 3-lead ECG dataset. 
     
     
         24 . The system of  claim 15 , wherein the first 3-lead ECG dataset is synchronized with the first 12-lead ECG dataset by further determining a representative beat for both the first 3-lead ECG dataset and the first 12-lead ECG dataset based on a median beat or an average beat from a plurality of heartbeats. 
     
     
         25 . The system of  claim 15 , wherein the first 3-lead ECG dataset is synchronized with the first 12-lead ECG dataset by further determining a representative beat for both the first 3-lead ECG dataset and the first 12-lead ECG dataset by selecting a median heartbeat from each of the first 12-lead ECG dataset and the first 3-lead ECG dataset. 
     
     
         26 . The system of  claim 15 , wherein the set of linear transformation parameters comprises a set of transformation matrices that synthesize the first 12-lead ECG dataset from the first 3-lead ECG dataset. 
     
     
         27 . The system of  claim 15 , wherein the instructions are further configured to output the second 12-lead ECG dataset. 
     
     
         28 . The system of  claim 27 , wherein outputting the second 12-lead ECG dataset comprises displaying the second 12-lead ECG dataset.

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